Results 11 to 20 of about 4,926 (194)
Differential Mobility Separation of Leukotrienes and Protectins [PDF]
Analytical Chemistry, 2015 Differential mobility spectrometry (DMS) is capable of separating stereoisomeric molecular ions based on their mobility in an oscillating electrical field with an asymmetric waveform. Thus, it is an "orthogonal" technique to chromatography and (tandem) mass spectrometry.
Jónasdóttir, Hulda +7 more
core +5 more sources
Docosahexaenoic acid, protectins and dry eye [PDF]
Current Opinion in Clinical Nutrition and Metabolic Care, 2011 To report recent data on the potential role of omega-3 fatty acids, in particular docosahexaenoic acid and its derivatives, in the treatment of dry eye syndrome.Dietary supplementation with polyunsaturated fatty acids yields positive results in the improvement of dry eye signs and symptoms.
Maria S, Cortina, Haydee E P, Bazan
openaire +3 more sources
Resolvins and protectins: mediating solutions to inflammation [PDF]
British Journal of Pharmacology, 2009 Resolution of inflammation has historically been viewed as a passive process, occurring as a result of the withdrawal of pro‐inflammatory signals, including lipid mediators such as leukotrienes and prostaglandins. Thus, most anti‐inflammatory drugs have traditionally targeted primarily mediator pathways that are engaged at the onset of inflammation ...
Payal, Kohli, Bruce D, Levy
openaire +3 more sources
Docosahexaenoic acid, protectin synthesis: relevance against atherothrombogenesis [PDF]
Proceedings of the Nutrition Society, 2013 DHA is an abundant nutrient from marine lipids: its specific biological effects have been investigated in human volunteers, taking into consideration the dose effects. We report herein that, at dosages below 1 g/d, DHA proved to be effective in lowering blood platelet function and exhibited an ‘antioxidant’ effect.
Michel, Lagarde +6 more
core +4 more sources
Can endogenous lipid molecules serve as predictors and prognostic markers of coronary heart disease?
Lipids in Health and Disease, 2008 Dyslipidemia, and inflammatory markers: high-sensitivity C-reactive protein (hs-CRP), myeloperoxidase (MPO), lipoprotein associated phospholipase A2(Lp-PLA2), and lipid peroxides (LP) are insufficient to predict the onset, extent, and prognosis of CHD ...
Das Undurti N
doaj +2 more sources
Synthesis, Structural Confirmation, and Biosynthesis of 22-OH-PD1n-3 DPA
Molecules, 2019 PD1n-3 DPA belongs to the protectin family of specialized pro-resolving lipid mediators. The protectins are endogenously formed mediators that display potent anti-inflammatory properties and pro-resolving bioactivities and have attracted interest in drug
Jannicke Irina Nesman +5 more
doaj +2 more sources
Lipids in Health and Disease, 2010 The high incidence of insulin resistance and the metabolic syndrome in South Asians remains unexplained. I propose that a defect in the activity of Δ6 and Δ5 desaturases and consequent low plasma and tissue concentrations of polyunsaturated fatty acids ...
Das Undurti N
doaj +2 more sources
Ageing: Is there a role for arachidonic acid and other bioactive lipids? A review
Journal of Advanced Research, 2018 Ageing is inevitable. Recent studies suggest that it could be delayed. Low-grade systemic inflammation is seen in type 2 diabetes mellitus, hypertension and endothelial dysfunction that are common with increasing age.
Undurti N. Das
doaj +2 more sources
Molecular Circuits of Resolution in Renal Disease [PDF]
The Scientific World Journal, 2010 Inflammation is a common feature of renal pathology. Lipid mediators, such as lipoxins, resolvins, and protectins, can actively promote the resolution of inflammation by inhibiting polymorphonuclear cell infiltration to the site of inflammation, shifting
Emma Börgeson, Catherine Godson
doaj +2 more sources
Role of omega-3 fatty acids and their metabolites in asthma and allergic diseases
Allergology International, 2015 Omega-3 fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are found naturally in fish oil and are commonly thought to be anti-inflammatory nutrients, with protective effects in inflammatory diseases including asthma and allergies ...
Jun Miyata, Makoto Arita
doaj +2 more sources