Results 41 to 50 of about 4,926 (194)
Journal of Lipid Research, 2013 Placental inflammation is associated with several pregnancy disorders. Inflammation is limited by anti-inflammatory and proresolving mechanisms, the latter partly mediated by resolvins and protectins derived from omega-3 polyunsaturated fatty acids (n ...
Megan L. Jones +6 more
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Frontiers in Psychiatry, 2020 Inflammation has been identified as one of the main pathophysiological mechanisms underlying neuropsychiatric and neurodegenerative disorders. Despite the role of inflammation in those conditions, there is still a lack of effective anti-inflammatory ...
Juliette Giacobbe +4 more
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Functional metabolomics reveals novel active products in the DHA metabolome
Frontiers in Immunology, 2012 Endogenous mechanisms for successful resolution of an acute inflammatory response and the local return to homeostasis are of interest because excessive inflammation underlies many human diseases.
Masakazu eShinohara +2 more
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Molecular Circuits of Resolution: Formation and Actions of Resolvins and Protectins [PDF]
The Journal of Immunology, 2005 Abstract The cellular events underlying the resolution of acute inflammation are not known in molecular terms. To identify anti-inflammatory and proresolving circuits, we investigated the temporal and differential changes in self-resolving murine exudates using mass spectrometry-based proteomics and lipidomics.
Gerard L, Bannenberg +7 more
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Современная ревматология, 2016 Inflammation is the most important element in the pathogenesis of major human diseases. It determines the fundamental value of anti-inflammatory therapy in the modern concept of targeted pathogenetic treatment.
A. E. Karateev, T. L. Aleinikova
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Prostanoids and Resolution of Inflammation – Beyond the Lipid-Mediator Class Switch
Frontiers in Immunology, 2021 Bioactive lipid mediators play a major role in regulating inflammatory processes. Herein, early pro-inflammatory phases are characterized and regulated by prostanoids and leukotrienes, whereas specialized pro-resolving mediators (SPM), including lipoxins,
Tobias Schmid +4 more
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Is There a Role for Bioactive Lipids in the Pathobiology of Diabetes Mellitus?
Frontiers in Endocrinology, 2017 Inflammation, decreased levels of circulating endothelial nitric oxide (eNO) and brain-derived neurotrophic factor (BDNF), altered activity of hypothalamic neurotransmitters (including serotonin and vagal tone) and gut hormones, increased concentrations ...
Undurti N. Das, Undurti N. Das
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Frontiers in Pharmacology, 2019 A western type diet and lifestyle play an important role in the development of chronic diseases, yet little insight into the precise cellular and biomolecular mechanisms has emerged. It is known that an unbalanced diet may result in obesity and diabetes.
Trond Vidar Hansen +2 more
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Protectin DX as a therapeutic strategy against frailty in mice
GeroScience, 2023 AbstractFrailty in aging is driven by the dysregulation of multiple biological pathways. Protectin DX (PDX) is a docosahexaenoic acid (DHA)-derived molecule that alleviates many chronic inflammatory disorders, but its potential effects on frailty remain unknown.
Laís R. Perazza +4 more
openaire +2 more sources
Frontiers in Immunology, 2021 Viral pneumonias are a major cause of morbidity and mortality, owing in part to dysregulated excessive lung inflammation, and therapies to modulate host responses to viral lung injury are urgently needed.
Katherine H. Walker +5 more
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