Results 61 to 70 of about 4,631 (175)

Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators

Allergy, EarlyView.
Jaime Bernaola, José Antonio Cañas, Álvaro Arranz‐Fragua, José Manuel Rodrigo‐Muñoz, Daniel Rodríguez‐González, Antonio Serrano‐Santiago, Gema Guillén‐Sánchez, Alma Martínez Fernández, Marcela Valverde‐Monge, Diana Betancor, Erwin Javier Pinillos‐Robles, Claudia Rodríguez‐Busto, María Jesús Rodríguez‐Nieto, Joaquín Sastre, Victoria del Pozo   +14 more
wiley   +1 more source

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun, Linqing Wen, Shiyun Tang, Lu Liu, Nianzhi Chen   +4 more
wiley   +1 more source

Omega fatty acids and resolution of inflammation: A new twist in an old tale

Journal of Indian Society of Periodontology, 2010
Identification of the factors that regulate immune tolerance and control the appearance of exacerbated inflammatory conditions is crucial for the development of new therapies of inflammatory and autoimmune diseases.
Mittal Antush, Ranganath V, Nichani Ashish   +2 more
doaj  

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, Volume 15, Issue 27, 17 July 2026.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Engineered probiotics platform for resolvin E1 biosynthesis confers protection against inflammatory disease

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
An engineered EcN‐RvE1 probiotic platform enables sustained biosynthesis of the pro‐resolving mediator RvE1 via inducible COX2/5‐LOX expression. Oral administration achieves long‐term intestinal persistence and systemic anti‐inflammatory effects in murine models of acute inflammation and colitis, offering a promising oral therapeutic strategy for ...
Xiaoxiao Li, Jiejing Lin, Qingqing Liu, Yiqun Wu, Qian Wu, Zewei Zhao, Yi Cai, Shengliang Lin, Zijie Zheng, Xinpan Chen, Jin Li, Zhonghan Yang   +11 more
wiley   +1 more source

Inflammaging: Experimental Insights and Translational Advances

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Inflammaging is a chronic, low‐grade, sterile inflammation associated with aging that contributes to age‐related diseases and functional decline. Recent research suggests that targeting inflammaging through senolytics, metabolic modulators, microbiome‐based interventions, and lifestyle modifications may help improve healthspan, reduce chronic disease ...
Andrea Cossarizza
wiley   +1 more source

Arachidonic acid and other unsaturated fatty acids and some of their metabolites function as endogenous antimicrobial molecules: A review

Journal of Advanced Research, 2018
Our body is endowed with several endogenous anti-microbial compounds such as interferon, cytokines, free radicals, etc. However, little attention has been paid to the possibility that lipids could function as antimicrobial compounds. In this short review,
Undurti N. Das
doaj   +1 more source

Omega‐3 Long‐Chain Polyunsaturated Fatty Acid Metabolite 16‐Hydroxydocosahexaenoic Acid Strengthens Non‐Small Cell Lung Cancer Radiosensitivity Through Peroxisome Proliferator‐Activated Receptor γ

Food Frontiers, Volume 7, Issue 4, July 2026.
This study revealed a novel mechanism by which ω‐3 LCPUFA metabolism regulated NSCLC cell radiosensitivity. Specific ω‐3 LCPUFA metabolite 16‐HDHA plasma levels were elevated in the radiosensitive NSCLC patients and enhanced the cytotoxic effects of radiation on NSCLC cells.
Mengqin Wang, Jiang Luo, Mini Zhang, Shuling Li, Jiawen Tang, Qingwei Wang, Yuzhu Wu, Ziyu Jiang, Conghua Xie, Yan Gong   +9 more
wiley   +1 more source

Can Inflammation-Resolution Provide Clues to Treat Patients According to Their Plaque Phenotype?

Frontiers in Pharmacology, 2019
Inflammation-resolution is an active process that is governed in part by specialized pro-resolving mediators (SPMs) such as lipoxins, resolvins, protectins, and maresins.
Gabrielle Fredman
doaj   +1 more source

Roles, Actions, and Therapeutic Potential of Specialized Pro-resolving Lipid Mediators for the Treatment of Inflammation in Cystic Fibrosis

Frontiers in Pharmacology, 2019
Non-resolving inflammation is the main mechanism of morbidity and mortality among patients suffering from cystic fibrosis (CF), the most common life-threatening human genetic disease.
Antonio Recchiuti, Antonio Recchiuti, Domenico Mattoscio, Domenico Mattoscio, Elisa Isopi, Elisa Isopi   +5 more
doaj   +1 more source