Results 81 to 90 of about 4,926 (194)
Journal of Advanced Research, 2018 Our body is endowed with several endogenous anti-microbial compounds such as interferon, cytokines, free radicals, etc. However, little attention has been paid to the possibility that lipids could function as antimicrobial compounds. In this short review,
Undurti N. Das
doaj +1 more source
British Journal of Pharmacology, Volume 183, Issue 9, Page 2049-2060, May 2026.Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma +9 more
wiley +1 more source
N−3 fatty acid supplementation in asthma management: A systematic review and meta‐analysis
, 2021 Laboratory and epidemiological evidence suggests that n−3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are beneficial in asthma prevention and possibly treatment through their anti- inflammatory effect.1 The ...
André Moreira +13 more
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Can Inflammation-Resolution Provide Clues to Treat Patients According to Their Plaque Phenotype?
Frontiers in Pharmacology, 2019 Inflammation-resolution is an active process that is governed in part by specialized pro-resolving mediators (SPMs) such as lipoxins, resolvins, protectins, and maresins.
Gabrielle Fredman
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Vagus nerve controls resolution and pro-resolving mediators of inflammation [PDF]
, 2015 Resolution of inflammation is now recognized as a biosynthetically active process involving pro-resolving mediators. Here, we show in zymosan-initiated peritoneal inflammation that the vagus nerve regulates local expression of netrin-1, an axonal ...
Rosenberger, Peter +4 more
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Molecular Pharmacology of Inflammation Resolution in Atherosclerosis
, 2022 Atherosclerosis is one of the most important problems of modern medicine as it is the leading cause of hospitalizations, disability, and mortality. The key role in the development and progression of atherosclerosis is the imbalance between the activation
Kotlyarova, Anna +3 more
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Frontiers in Pharmacology, 2019 Non-resolving inflammation is the main mechanism of morbidity and mortality among patients suffering from cystic fibrosis (CF), the most common life-threatening human genetic disease.
Antonio Recchiuti +5 more
doaj +1 more source
Mediators of Inflammation, 2018 Acute inflammatory responses are host-protective and normally self-limited; these responses can maintain cell homeostasis and promote defense against various infections and damage factors.
Shi Tang +4 more
doaj +1 more source
Journal of Lipid Research, 2013 Resolvins and protectins are important anti-inflammatory and pro-resolution compounds derived from the enzymatic oxidation of omega-3 fatty acids all-cis-5,8,11,14,17-eicosapentaenoic acid (EPA) and all-cis-4,7,10,13,16,19-docosahexaenoic acid (DHA).
Eleanor P. Dobson +3 more
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Pro-Resolving Lipid Mediators in the Pathophysiology of Asthma
Medicina, 2019 Asthma is one of the most important medical and social problems of our time due to the prevalence and the complexity of its treatment. Chronic inflammation that is characteristic of asthma is accompanied by bronchial obstruction, which involves various ...
Oxana Kytikova +4 more
doaj +1 more source