Results 91 to 100 of about 4,926 (194)

Docosahexanoic acid (DHA) reduces brain damage induced by reversible middle cerebral artery occlusion (MCAO) in mice

Zagazig Journal of Pharmaceutical Sciences, 2013
Stroke is a leading cause of death and permanent disability in adults worldwide. The only FDA-approved treatment for acute ischemic stroke is the intravenous recombinant tissue plasminogen activator (rt-PA) within 3 hours of onset Among the mechanisms ...
Waleed Barakat , Mohamed Mahrous , Mohamed Zakaria   +2 more
doaj   +1 more source

Propriétés anti-inflammatoires des oxylipines dérivées du DHA

, 2016
Flash Posters : Axe 2National audienceWhereas the anti-inflammatory properties and mechanisms of action of long chain. 3 PUFAs have been abundantly investigated, research gaps remain regarding the respective contribution and mechanisms of action of their
Mazur, André, Chinetti-Gbaguidi, Giulia, Joumard-Cubizolles, Laurie, Bayle, Dominique, Porta, A., Hennuyer, Nathalie, Oger, Camille, Galano, Jean-Marie, Staels, Bart, Gladine, Cécile, Zanoni, Giuseppe, Bosviel, Rémy, Durand, Thierry, Balas, Laurence, Copin, Corinne   +14 more
core   +1 more source

protectin

Citation: 'protectin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13614 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

, 2014
Inflammation is associated with the development of diseases characterized by altered nutrient metabolism. Although an acute inflammatory response is host-protective and normally self-limited, chronic low-grade inflammation associated with metabolic ...
Clària, Joan, Charles N. Serhan, Serhan, Charles N., Matthew Spite, Joan Clària, Spite, Matthew   +5 more
core   +1 more source

Omega-3 fatty acid supplementation in horses

Revista Brasileira de Zootecnia, 2014
Polyunsaturated omega-3 fatty acids (n-3 PUFA) are a family of essential fatty acids with many biological activities. These fatty acids are incorporated into cell membranes, changing their structural and functional characteristics.
Tanja Hess, Trinette Ross-Jones
doaj   +1 more source

Reduced lipoxygenase and cyclooxygenase mediated signaling in PBMC of atopic dermatitis patients.

, 2013
Lipoxygenases (LOX) and cyclooxygenases (COX) are the main enzymes for poly-unsaturated fatty acid (PUFA) metabolism to highly bioactive prostaglandins, leukotrienes, thromboxanes and protectins.
Krisztián Gáspár, Mihály, Johanna, Johanna Mihály, Janine Gericke, Andrea Szegedi, Dániel Törőcsik, Rühl, Ralph, Gericke, Janine, Ralph Rühl, Gáspár, Krisztián, Szegedi, Andrea, Törőcsik, Dániel   +11 more
core   +1 more source

Low-dose pro-resolving mediators temporally reset the resolution response to microbial inflammation

Molecular Medicine
Background Specialized pro-resolving mediators (SPMs) promote resolution of inflammation, clear infections and stimulate tissue regeneration. These include resolvins, protectins, and maresins.
Charles N. Serhan, Nan Chiang, Robert Nshimiyimana   +2 more
doaj   +1 more source

Uncovering the Power of GPR18 Signalling: How RvD2 and Other Ligands Could Have the Potential to Modulate and Resolve Inflammation in Various Health Disorders

Molecules
The resolution of inflammation is the primary domain of specialised pro-resolving mediators (SPMs), which include resolvins, protectins, and their forms synthesised under the influence of aspirin and the maresins.
Ewelina Honkisz-Orzechowska, Dorota Łażewska, Grzegorz Baran, Katarzyna Kieć-Kononowicz   +3 more
doaj   +1 more source

Identification of inflammatory and proresolving lipid mediators in bone marrow and their lipidomic profiles with ovariectomy and omega-3 intake.

, 2008
Newly described lipoxygenase (LOX)-generated lipid mediators, that is, resolvins and protectins as well as lipoxins, are both anti-inflammatory and proresolving.
Raewyn C. Poulsen, Serhan, CN, Gotlinger, KH, Poulsen, RC, Charles N. Serhan, Marlena C. Kruger, Poulsen, Raewyn, Kruger, MC, Katherine H. Gotlinger   +8 more
core   +1 more source

Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis

, 2019
Omega-6 (n-6) and omega-3 (n-3) polyunsaturated fatty acids (PUFA) are the precursors of potent lipid mediators and play an important role in regulation of inflammation.
Dignass, Axel, Wang, Jingdong, Lu, Yan, Kang, Jing X., Hudert, Christian A., Weylandt, Karsten H., Serhan, Charles N., Hong, Song   +7 more
core   +1 more source