Results 71 to 80 of about 7,100 (207)
Molecular Circuits of Resolution in Renal Disease
The Scientific World Journal, 2010 Inflammation is a common feature of renal pathology. Lipid mediators, such as lipoxins, resolvins, and protectins, can actively promote the resolution of inflammation by inhibiting polymorphonuclear cell infiltration to the site of inflammation, shifting
Emma Börgeson, Catherine Godson
doaj +1 more source
Molecular Circuits of Resolution: Formation and Actions of Resolvins and Protectins [PDF]
The Journal of Immunology, 2005 Abstract The cellular events underlying the resolution of acute inflammation are not known in molecular terms. To identify anti-inflammatory and proresolving circuits, we investigated the temporal and differential changes in self-resolving murine exudates using mass spectrometry-based proteomics and lipidomics.
Gerard L, Bannenberg +7 more
openaire +3 more sources
British Journal of Pharmacology, EarlyView.Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma +9 more
wiley +1 more source
Long-chain omega-3 fatty acids and the brain: A review of the independent and shared effects of EPA, DPA and DHA [PDF]
, 2015 Omega-3 polyunsaturated fatty acids (PUFAs) exhibit neuroprotective properties and represent a potential treatment for a variety of neurodegenerative and neurological disorders.
Dyall, Simon
core +2 more sources
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: leukotrienes, lipoxins and resolvins [PDF]
, 2017 Atherogenesis is an inflammatory process with leukocytes infiltrating the arterial intima. The lipoxygenase pathways play a role in leukocyte recruitment through the generation of two classes of arachidonic acid lipid mediators, the leukotrienes and the ...
Hersberger, Martin
core
Lipidomics to analyze the influence of diets with different EPA:DHA ratios in the progression of Metabolic Syndrome using SHROB rats as a model [PDF]
, 2016 8 páginas, 4 tablasThe role of specific proportions of ω-3 EPA and DHA, in the modulation of inflammation and oxidative stress markers associated to the progression of Metabolic Syndrome was investigated.
Dasilva, Gabriel +7 more
core +1 more source
Periodontology 2000, EarlyView.Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje +3 more
wiley +1 more source
Algae: Critical Sources of Very Long-Chain Polyunsaturated Fatty Acids
Biomolecules, 2019 Polyunsaturated fatty acids (PUFAs), which are divided into n-3 and n-6 classes, are essential for good health in humans and many animals. They are metabolised to lipid mediators, such as eicosanoids, resolvins and protectins.
John L. Harwood
doaj +1 more source
Histiocytes: Multifaceted Regulators of Health and Disease
Veterinary Clinical Pathology, EarlyView.ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source