Results 81 to 90 of about 7,100 (207)

Exploring the nexus: Clinical and physiological correlation between cardiovascular disease and colorectal cancer

Experimental Physiology, EarlyView.
Abstract Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide, traditionally studied as distinct pathologies. However, emerging evidence suggests a significant physiological and molecular overlap between these conditions, indicating that they might share common pathophysiological pathways. The
Mohamad Bashir, Ali Murtada, Matti Jubouri, Wael Awad, Ian Williams, Damian M. Bailey   +5 more
wiley   +1 more source

Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarctionResearch in context

EBioMedicine, 2019
Background: Termination of acute inflammation is an active process orchestrated by lipid mediators (LM) derived from polyunsaturated fatty acids, referred to as specialized pro-resolving mediators (SPM).
Linn E. Fosshaug, Romain A. Colas, Anne K. Anstensrud, Ida Gregersen, Ståle Nymo, Ellen L. Sagen, Annika Michelsen, Leif E. Vinge, Erik Øie, Lars Gullestad, Bente Halvorsen, Trond V. Hansen, Pål Aukrust, Jesmond Dalli, Arne Yndestad   +14 more
doaj   +1 more source

Synthesis of protectin D1 analogs: novel pro-resolution and radiotracer agents [PDF]

Organic & Biomolecular Chemistry, 2018
The first synthetic analog of protectin D1 with potent pro-resolving and anti-inflammatory properties is reported.
J. E. Tungen, M. Aursnes, S. Ramon, R. A. Colas, C. N. Serhan, D. E. Olberg, S. Nuruddin, F. Willoch, T. V. Hansen   +8 more
openaire   +2 more sources

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li, Weijian Wang, Juncheng Zhan, Yuxiang Xiao, Xiaoping Chen, Chen Su, Peng Zhu   +6 more
wiley   +1 more source

Molecular Circuits of Resolution in Airway Inflammation

The Scientific World Journal, 2010
Inflammatory diseases of the lung are common, cause significant morbidity, and can be refractory to therapy. Airway responses to injury, noxious stimuli, or microbes lead to leukocyte recruitment for host defense.
Troy Carlo, Bruce D. Levy
doaj   +1 more source

Effects of Fish Oil Supplementation on Protease Levels in the Microenvironment of Chronic Venous Leg Ulcers: A Randomized Clinical Trial [PDF]

, 2017
In the U.S. alone, the average annual incidence of chronic venous leg ulcers (CVLUs) in individuals aged 65+ is 2.2% with payer burden reaching ~$35 billion. Moreover, the incidence is expected to rise dramatically because CVLUs are associated with aging
Sales, Michelle
core  

Placenta‐derived extracellular vesicles: Signal messengers shuttling across the maternal‐fetal barrier

Interdisciplinary Medicine, Volume 4, Issue 2, March 2026.
In normal pregnancy, PEVs help maintain maternal–fetal immune tolerance while enabling controlled immune activation, promote endothelial migration, and support trophoblast invasion and syncytialization, strengthening antimicrobial defense. In pregnancy‐related disorders, dysregulated PEV signaling may drive endothelial dysfunction and hypertension, BBB
Jiale Du, Maliang Tao, Yanxuan Xiao, Zhijian Wang, Bo Situ, Lei Zheng   +5 more
wiley   +1 more source

Omega fatty acids and resolution of inflammation: A new twist in an old tale

Journal of Indian Society of Periodontology, 2010
Identification of the factors that regulate immune tolerance and control the appearance of exacerbated inflammatory conditions is crucial for the development of new therapies of inflammatory and autoimmune diseases.
Mittal Antush, Ranganath V, Nichani Ashish   +2 more
doaj  

Eicosanoids in skin inflammation. [PDF]

, 2012
NoEicosanoids play an integral part in homeostatic mechanisms related to skin health and structural integrity. They also mediate inflammatory events developed in response to environmental factors, such as exposure to ultraviolet radiation, and ...
Agarwal, Albanesi, Andersen, Andoh, Andoh, Anna Nicolaou, Baer, Baer, Baron, Bergers, Black, Boeglin, Boguniewicz, Boyce, Brash, Bray, Bryniarski, Burke, Burr, Calder, Calder, Carlson, Carsberg, Chapkin, Chen, Chene, Church, Colombe, Crespy, De Nucci, Dennis, Doepping, Du, Epp, Fincham, Fisher, Fogh, Fogh, Fogh, Ford-Hutchinson, Gledhill, Goetzl, Gonzalez, Grabbe, Grabbe, Grant, Gresham, Grundmann, Gueck, Hansen, Harris, Honda, Honda, Honma, Hruza, Ikai, Ikai, Ikai, Janssen-Timmen, Jisaka, Judson, Judson, Kanda, Keeney, Keeney, Kolgen, Konger, Kragballe, Kragballe, Krieg, Kudo, Kuhn, Ladd, Leong, Levy, Lowes, Lu, Lu, Martin, Masoodi, Massey, Matsushima, Mayer, Mayser, McCusker, McDaniel, Millard, Miller, Miller, Milne, Muller, Nakajima, Narayanan, Nichols, Nicolaou, Nicolaou, Oka, Oyoshi, Parekh, Pentland, Pietrzak, Pilkington, Proksch, Rhodes, Rhodes, Ricketts, Rijken, Ruzicka, Sato, Satoh, Schafer, Schweiger, Scott, Scott, Scott, Serhan, Serhan, Shimura, Singh, Sjursen, Spanbroek, Stark, Straus, Sugimoto, Tai, Takeda, Ueno, Watanabe, Weber, Xi, Yoo, Zheng, Zhou, Ziboh, Ziboh, Ziboh, Ziboh, Ziboh, Zulfakar, Zuo   +139 more
core   +1 more source

Adjunctive Therapies in Periodontitis: Current Concepts and the Future

Journal of Periodontal Research, Volume 61, Issue 2, Page 138-164, February 2026.
This graphical abstract summarizes the translational pathway from preclinical research to clinical implementation of adjunctive therapies for periodontitis, highlighting key barriers, innovative therapeutic strategies, and emerging tools that aim to bridge experimental discoveries with patient care.
Rafael Scaf de Molon, Joao Paulo Steffens, Erica Dorigatti de Avila, Wim Teughels, Thomas E. Van Dyke   +4 more
wiley   +1 more source