Plant-derived insoluble protein aggregates: Formation mechanisms, influencing factors, solubilization, functional properties, and applications [PDF]
Food Chemistry: XPlant protein is a high-quality protein resource and has been widely used in various fields of the food industry. However, during food processing, especially thermal processing, enzymatic hydrolysis and enzymatic cross-linking, insoluble protein ...
Yanli Ji +5 more
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Quantitative Profiling of Nanoscopic Protein Aggregates Reveals Specific Fingerprint of TDP‐43‐Positive Assemblies in Motor Neuron Disease [PDF]
Advanced ScienceAbnormal aggregation of TAR DNA‐binding protein 43 (TDP‐43) is a pathological hallmark of motor neuron disease (MND), yet current methods for quantifying these aggregates in biological samples remain limited in sensitivity and resolution.
Dezerae Cox +9 more
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Magnetic protein aggregates generated by supramolecular assembly of ferritin cages - a modular strategy for the immobilization of enzymes [PDF]
Frontiers in Bioengineering and BiotechnologyIntroductionEfficient and cost-effective immobilization methods are crucial for advancing the utilization of enzymes in industrial biocatalysis. To this end, in vivo immobilization methods relying on the completely biological production of immobilizates ...
Gizem Ölçücü +8 more
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Liquid–Liquid Phase Separation and Protective Protein Aggregates in Bacteria [PDF]
Molecules, 2023 Liquid–liquid phase separation (LLPS) and the formation of membraneless organelles (MLOs) contribute to the spatiotemporal organization of various physiological processes in the cell.
Dorota Kuczyńska-Wiśnik +2 more
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Frontiers in Nutrition, 2022 This study was carried out to investigate the effect of heat pre-treatment of pea proteins at different pH values on the formation of functional protein aggregates. A 10% (w/v) aqueous mixture of pea protein concentrate (PPC) was adjusted to pH 3.0, 5.0,
Nancy D. Asen +2 more
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Protein aggregate myopathies [PDF]
Neurology India, 2005 Protein aggregate myopathies (PAM) are an emerging group of muscle diseases characterized by structural abnormalities. Protein aggregate myopathies are marked by the aggregation of intrinsic proteins within muscle fibers and fall into four major groups or conditions: (1) desmin-related myopathies (DRM) that include desminopathies, a-B ...
M C, Sharma, H H, Goebel
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Amyloids and protein aggregation
Chemical Science, 2023 Sara Linse and Tuomas Knowles introduce the Chemical Science themed collection on the topic of amyloids and protein aggregation.
Sara Linse, Tuomas Knowles
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Protein aggregation and bioprocessing [PDF]
The AAPS Journal, 2006 Protein aggregation is a common issue encountered during manufacture of biotherapeutics. It is possible to influence the amount of aggregate produced during the cell culture and purification process by carefully controlling the environment (eg, media components) and implementing appropriate strategies to minimize the extent of aggregation.
Mary E M, Cromwell +2 more
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[PRION+] States Are Associated with Specific Histone H3 Post-Translational Modification Changes
Pathogens, 2022 Prions are proteins able to take on alternative conformations and propagate them in a self-templating process. In Saccharomyces cerevisiae, prions enable heritable responses to environmental conditions through bet-hedging mechanisms.
Samantha N. Cobos +9 more
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Changes in Protein Non-Covalent Bonds and Aggregate Size during Dough Formation
Foods, 2020 This research investigated changes in the amounts and sizes of monomeric proteins and protein aggregates during dough mixing, with a focus on the contribution of non-covalent bonds in the aggregation of gluten proteins.
Sonoo Iwaki +4 more
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