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Plant-derived insoluble protein aggregates: Formation mechanisms, influencing factors, solubilization, functional properties, and applications [PDF]
Food Chemistry: XPlant protein is a high-quality protein resource and has been widely used in various fields of the food industry. However, during food processing, especially thermal processing, enzymatic hydrolysis and enzymatic cross-linking, insoluble protein ...
Yanli Ji +5 more
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Quantitative Profiling of Nanoscopic Protein Aggregates Reveals Specific Fingerprint of TDP‐43‐Positive Assemblies in Motor Neuron Disease [PDF]
Advanced ScienceAbnormal aggregation of TAR DNA‐binding protein 43 (TDP‐43) is a pathological hallmark of motor neuron disease (MND), yet current methods for quantifying these aggregates in biological samples remain limited in sensitivity and resolution.
Dezerae Cox +9 more
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Magnetic protein aggregates generated by supramolecular assembly of ferritin cages - a modular strategy for the immobilization of enzymes [PDF]
Frontiers in Bioengineering and BiotechnologyIntroductionEfficient and cost-effective immobilization methods are crucial for advancing the utilization of enzymes in industrial biocatalysis. To this end, in vivo immobilization methods relying on the completely biological production of immobilizates ...
Gizem Ölçücü +8 more
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Liquid–Liquid Phase Separation and Protective Protein Aggregates in Bacteria [PDF]
Molecules, 2023 Liquid–liquid phase separation (LLPS) and the formation of membraneless organelles (MLOs) contribute to the spatiotemporal organization of various physiological processes in the cell.
Dorota Kuczyńska-Wiśnik +2 more
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Disease Models & Mechanisms, 2021 Spinocerebellar ataxia 3 (SCA3, also known as Machado–Joseph disease) is a neurodegenerative disease caused by inheritance of a CAG repeat expansion within the ATXN3 gene, resulting in polyglutamine (polyQ) repeat expansion within the ataxin-3 protein ...
Katherine J. Robinson +7 more
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Impact of Protein Aggregates on Sporulation and Germination of Bacillus subtilis. [PDF]
Microorganisms, 2023 Mortier J +4 more
europepmc +3 more sources
Protein Aggregates and Aggrephagy in Myopathies. [PDF]
Int J Mol Sci, 2023 Gibertini S +3 more
europepmc +3 more sources
Frontiers in Nutrition, 2022 This study was carried out to investigate the effect of heat pre-treatment of pea proteins at different pH values on the formation of functional protein aggregates. A 10% (w/v) aqueous mixture of pea protein concentrate (PPC) was adjusted to pH 3.0, 5.0,
Nancy D. Asen +2 more
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Protein aggregate myopathies [PDF]
Neurology India, 2005 Protein aggregate myopathies (PAM) are an emerging group of muscle diseases characterized by structural abnormalities. Protein aggregate myopathies are marked by the aggregation of intrinsic proteins within muscle fibers and fall into four major groups or conditions: (1) desmin-related myopathies (DRM) that include desminopathies, a-B ...
M C, Sharma, H H, Goebel
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Protein aggregation and bioprocessing [PDF]
The AAPS Journal, 2006 Protein aggregation is a common issue encountered during manufacture of biotherapeutics. It is possible to influence the amount of aggregate produced during the cell culture and purification process by carefully controlling the environment (eg, media components) and implementing appropriate strategies to minimize the extent of aggregation.
Mary E M, Cromwell +2 more
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