Results 21 to 30 of about 486,105 (348)

When aggregation-induced emission meets protein aggregates [PDF]

open access: yesNational Science Review, 2021
There is an unmet demand for research tools to monitor the multistep protein aggregation process in live cells, a process that has been associated with a growing number of human diseases. Recently, AIEgens have been developed to directly monitor the entire protein aggregation process in test tubes and live cells.
Sicheng Tang, Songtao Ye, Xin Zhang
openaire   +2 more sources

Functional foods for mental health promotion

open access: yesJournal of Mahatma Gandhi Institute of Medical Sciences, 2020
Mental health problems and morbidities are increasing day by day. The etiology of mental health disorders is extremely complex and encompasses a range of genetic, dietary, emotional, and social as well as lifestyle factors.
Soumam Dutta, Sohini Roy, Sanchari Roy
doaj   +1 more source

Focus on the Protein Fraction of Sports Nutrition Supplements

open access: yesMolecules, 2022
Increasing awareness of balanced diet benefits is boosting the demand for high-protein food and beverages. Sports supplements are often preferred over traditional protein sources to meet the appropriate dietary intake since they are widely available on ...
Luisa Pellegrino   +5 more
doaj   +1 more source

Protein aggregates nucleate ice: the example of apoferritin [PDF]

open access: yes, 2020
Biological material has gained increasing attention recently as a source of ice-nucleating particles that may account for cloud glaciation at moderate supercooling.
Bittner, Alexander M.   +4 more
core   +1 more source

Protein aggregation and neurodegeneration [PDF]

open access: yesMethods, 2011
In 1997 Carrell and Lomas put forth the concept that many disorders, which appeared to be unlinked, arose from the same general mechanism that involved the abnormal unfolding and aggregation of various underlying proteins [1]. The flux of proteins through pathways for formation of amyloid-like aggregates was proposed to be the mechanism for ...
Katie J, Mayo, Douglas M, Cyr
openaire   +2 more sources

Localization of protein aggregation in Escherichia coli is governed by diffusion and nucleoid macromolecular crowding effect [PDF]

open access: yes, 2013
Aggregates of misfolded proteins are a hallmark of many age-related diseases. Recently, they have been linked to aging of Escherichia coli (E. coli) where protein aggregates accumulate at the old pole region of the aging bacterium.
Berry, Hugues   +8 more
core   +7 more sources

Protein aggregation in silico [PDF]

open access: yesTrends in Biotechnology, 2007
Protein aggregation is a challenge to the successful manufacture of protein therapeutics; it can impose severe limitations on purification yields and compromise formulation stability. Advances in computer power, and the wealth of computational studies pertaining to protein folding, have facilitated the development of molecular simulation as a tool to ...
Troy, Cellmer   +3 more
openaire   +2 more sources

The ER Stress Surveillance (ERSU) pathway regulates daughter cell ER protein aggregate inheritance

open access: yeseLife, 2015
Stress induced by cytoplasmic protein aggregates can have deleterious consequences for the cell, contributing to neurodegeneration and other diseases.
Francisco J Piña, Maho Niwa
doaj   +1 more source

Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins [PDF]

open access: yes, 2020
Background Mutations in pre-mRNA splicing factor PRPF31 can lead to retinitis pigmentosa (RP). Although the exact disease mechanism remains unknown, it has been hypothesized that haploinsufficiency might be involved in the ...
Aramburu, Ana   +13 more
core   +2 more sources

Glutamine Synthetase 1 Increases Autophagy Lysosomal Degradation of Mutant Huntingtin Aggregates in Neurons, Ameliorating Motility in a Drosophila Model for Huntington’s Disease

open access: yesCells, 2020
Glutamine Synthetase 1 (GS1) is a key enzyme that catalyzes the ATP-dependent synthesis of l-glutamine from l-glutamate and is also member of the Glutamate Glutamine Cycle, a complex physiological process between glia and neurons that controls glutamate ...
Luisa Vernizzi   +14 more
doaj   +1 more source

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