Results 121 to 130 of about 1,466,359 (163)

Adenosine Triphosphate: The Primordial Molecule That Controls Protein Homeostasis and Shapes the Genome-Proteome Interface. [PDF]

Biomolecules
Song J.
europepmc   +1 more source

Ccr4-not ubiquitin ligase signaling regulates ribosomal protein homeostasis and inhibits 40S ribosomal autophagy. [PDF]

J Biol Chem
Johnson DL, Kumar R, Kakhniashvili D, Pfeffer LM, Laribee RN.   +4 more
europepmc   +1 more source

Super enhancer acquisition drives expression of oncogenic PPP1R15B that regulates protein homeostasis in multiple myeloma. [PDF]

Nat Commun
Xiong S, Zhou J, Tan TK, Chung TH, Tan TZ, Toh SH, Tang NXN, Jia Y, See YX, Fullwood MJ, Sanda T, Chng WJ.   +11 more
europepmc   +1 more source

Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain. [PDF]

Cell
Scott-Hewitt N, Mahoney M, Huang Y, Korte N, Yvanka de Soysa T, Wilton DK, Knorr E, Mastro K, Chang A, Zhang A, Melville D, Schenone M, Hartigan C, Stevens B.   +13 more
europepmc   +1 more source

Exosomal misfolded proteins released by cancer stem cells: dual functions in balancing protein homeostasis and orchestrating tumor progression. [PDF]

Discov Oncol
Bhattacharya A, Chatterji U.
europepmc   +1 more source

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Citrulline production and protein homeostasis

Current Opinion in Clinical Nutrition & Metabolic Care, 2019
Protein homeostasis is crucial for maintaining cell functions. Citrulline, an endogenous amino acid, is considered as an efficient source of arginine at systemic and cellular level. Accumulating evidence, obtained from citrulline supplementation studies, suggest anabolic properties especially in malnourished rodents and human.
Antonin, Ginguay, Jean-Pascal, De Bandt
openaire   +2 more sources

Protein homeostasis from the outside in

Nature Cell Biology, 2020
Secretory proteins undergo multiple rounds of co- and post-translational quality control checks inside the cell, but how their integrity is maintained outside the cell is an emerging topic. A study establishes a model system to investigate how the extracellular proteome is protected and integrates its findings into existing immune pathways.
Brant M, Webster, Holly K, Gildea, Andrew, Dillin   +2 more
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Protein Intake and Calcium Homeostasis

1994
The earliest study documenting the relationship between dietary protein and urinary calcium was published 70 years ago. Sherman (1920) reported that an all-meat diet fed to humans increased urinary calcium. Twenty years later McCance et al. (1942) confirmed this observation by showing that peptones, gluten, gelatin or egg white added to the diet ...
J E, Kerstetter, L H, Allen
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Mitochondrial control of cellular protein homeostasis

Biochemical Journal, 2020
Mitochondria are involved in several vital functions of the eukaryotic cell. The majority of mitochondrial proteins are coded by nuclear DNA. Constant import of proteins from the cytosol is a prerequisite for the efficient functioning of the organelle. The protein import into mitochondria is mediated by diverse import pathways and is continuously under
Karthik Mohanraj, Urszula Nowicka, Agnieszka Chacinska   +2 more
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Small-Molecule Modulation of Protein Homeostasis

Chemical Reviews, 2017
Control of protein levels by nucleic-acid-based technologies has proven to be a useful research tool but lacks the advantages of small molecules with respect to cell permeability, temporal control, and the potential generation of therapeutics. In this Review, we discuss the technologies available for the control of intracellular protein levels with ...
George M. Burslem, Craig M. Crews
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