Results 121 to 130 of about 1,938,673 (304)

A proteomic and phosphoproteomic analysis of Oryza sativa plasma membrane and vacuolar membrane [PDF]

, 2008
Proteomic and phosphoproteomic analyses of rice shoot and root tonoplast-enriched and plasma membrane-enriched membrane fractions were carried out to look at tissue-specific expression, and to identify putative regulatory sites of membrane transport ...
Ahn, Alexandersson, Armengaud, Banuelos, Benschop, Brugiere, Carter, Chrispeels, Ducos, Dunkley, Endler, Gaxiola, Gierth, Jacquinod, Komatsu, Larsson, Loque, Lüttge, Ma, Maathuis, Maathuis, Marmagne, Morsomme, Niittyla, Nühse, Nühse, Paszkowski, Peltier, Pighin, Rentsch, Sancenon, Tanaka, Tornroth-Horsefield, Toyofuku, Vitart, Whiteman, Wintz, Wu, Yazaki   +38 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Shear stress regulation of miR-93 and miR-484 maturation through nucleolin. [PDF]

, 2019
Pulsatile shear (PS) and oscillatory shear (OS) elicit distinct mechanotransduction signals that maintain endothelial homeostasis or induce endothelial dysfunction, respectively.
Chen, Lili, Chen, Shanshan, Chien, Shu, Gongol, Brendan, Han, Yue, He, Ming, Huang, Po-Hsun, Johnson, David A, Kang, Jian, Li, Jie, Li, Yi-Shuan, Liu, Jun-Hui, Lytle, Christian, Marin, Traci, Martin, Marcy, Shyy, John Y-J, Sun, Wei, Wang, Shen-Chih, Zhang, Jiao   +18 more
core  

Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression [PDF]

, 2018
The complete mechanism accounting for the progression from simple steatosis to steatohepatitis in nonalcoholic fatty liver disease (NAFLD) has not been elucidated.
Avolio, Carlo, Bellanti, Francesco, Blonda, Maria, di Bello, Giorgia, Facciorusso, Antonio, Iannelli, Giuseppina, Iuliano, Luigi, Poli, Giuseppe, Serviddio, Gaetano, Tamborra, Rosanna, Vendemiale, Gianluigi, Villani, Rosanna   +11 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Concise Review: The Potential Use of Intestinal Stem Cells to Treat Patients With Intestinal Failure. [PDF]

, 2016
: Intestinal failure is a rare life-threatening condition that results in the inability to maintain normal growth and hydration status by enteral nutrition alone.
Dunn, James CY, Hong, Sung Noh, Martín, Martín G, Stelzner, Matthias   +3 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Transcriptomic analyses of Pinctada fucata martensii responses under stress of titanium dioxide nanoparticles

Frontiers in Marine Science
Titanium dioxide nanoparticles (TiO2-NPs) released into the environment is becoming more prevalent due to their increased usage, marine TiO2-NPs contamination is escalating concerns in coastal areas.
Fengfeng Li, Jiaen Liu, Zixin Gao, Chuangye Yang, Liwei Sun, Yongshan Liao, Yongshan Liao, Yuewen Deng, Yuewen Deng, Yuewen Deng, Yuewen Deng   +10 more
doaj   +1 more source

Alterations in hepatic miRNA expression during negative energy balance in postpartum dairy cattle [PDF]

, 2014
peer-reviewedBackground Negative energy balance (NEB), an altered metabolic state, occurs in early postpartum dairy cattle when energy demands to support lactation exceed energy intake.
Fatima, Attia, Morris, Dermot G., O'Boyle, Padraig, Seoighe, Cathal, Waters, Sinead M.   +4 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source