Results 11 to 20 of about 6,367,317 (393)
Nuclear protein kinase C isoforms and apoptosis
European Journal of Histochemistry, 2009 The process of apoptosis is regulated at multiple levels through phosphorylation by several different protein kinases. The protein kinase C (PKC) family of isozymes have been shown to exert both inhibitory and stimulatory influences on apoptosis.
AM Martelli, G Mazzotti, S Capitani
doaj +8 more sources
HETEROGENEITY OF PRESYNAPTIC PROTEINS: DO NOT FORGET ISOFORMS [PDF]
Frontiers in Cellular Neuroscience, 2013 Analysis of presynaptic protein expression in glutamatergic and GABAergic central synapses performed in several laboratories and with different techniques is unveiling a complex scenario, largely because each presynaptic protein exists in several ...
Luca eBragina +10 more
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From protein-protein to isoform-isoform interactions: the toolkit to map alternative splicing to interactome [PDF]
From protein-protein to isoform-isoform interactions: the toolkit to map alternative splicing to interactome, 2023 Alternative splicing (AS) can impact protein structure and lead to protein-protein interaction (PPI) rewiring. Available PPI networks neglect alternative splicing isoforms: as interactions might happen only between a subset of isoforms, the PPI network contains both false-positive and false-negative interactions.
Olga Tsoy +6 more
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Alternative splicing in ABA signaling during seed germination
Frontiers in Plant Science, 2023 Seed germination is an essential step in a plant’s life cycle. It is controlled by complex physiological, biochemical, and molecular mechanisms and external factors.
Ewa Sybilska, Agata Daszkowska-Golec
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Characteristics of Human OAS1 Isoform Proteins [PDF]
Viruses, 2020 The human OAS1 (hOAS1) gene produces multiple possible isoforms due to alternative splicing events and sequence variation among individuals, some of which affect splicing. The unique C-terminal sequences of the hOAS1 isoforms could differentially affect synthetase activity, protein stability, protein partner interactions and/or cellular localization ...
Han Di, Husni Elbahesh, Margo A. Brinton
openaire +3 more sources
On the Occurrence and Multimerization of Two-Polypeptide Phage Endolysins Encoded in Single Genes
Microbiology Spectrum, 2022 Bacteriophages (phages) and other viruses are extremely efficient in packing their genetic information, with several described cases of overlapping genes encoded in different open reading frames (ORFs).
Daniela Pinto +7 more
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Plant Proteoforms Under Environmental Stress: Functional Proteins Arising From a Single Gene
Frontiers in Plant Science, 2021 Proteins are directly involved in plant phenotypic response to ever changing environmental conditions. The ability to produce multiple mature functional proteins, i.e., proteoforms, from a single gene sequence represents an efficient tool ensuring the ...
Klára Kosová +4 more
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Cells, 2023 Synaptopodin-2 (SYNPO2) is a protein associated with the Z-disc in striated muscle cells. It interacts with α-actinin and filamin C, playing a role in Z-disc maintenance under stress by chaperone-assisted selective autophagy (CASA).
Keerthika Lohanadan +11 more
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Efficient Detection of the Alternative Spliced Human Proteome Using Translatome Sequencing
Frontiers in Molecular Biosciences, 2022 Alternative splicing (AS) isoforms create numerous proteoforms, expanding the complexity of the genome. Highly similar sequences, incomplete reference databases and the insufficient sequence coverage of mass spectrometry limit the identification of AS ...
Chun Wu +11 more
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Molecular Neurodegeneration, 2020 Identified as an Alzheimer’s disease (AD) susceptibility gene by genome wide-association studies, BIN1 has 10 isoforms that are expressed in the Central Nervous System (CNS).
M. Taga +18 more
semanticscholar +1 more source