Results 21 to 30 of about 242,506 (191)
Type I protein is a slow isoform of troponin T [PDF]
FEBS Letters, 1988 Type I protein, a myofibrillar protein thought to be specific to slow‐twitch skeletal muscle fibers, was purified. Two‐dimensional electrophoresis indicated its identity with the purified slow troponin‐T1s isoform. Immunochemical analyses using antibodies raised against type I protein and slow Tn‐T1s, further substantiated the identity of the two ...
T. Schmitt, Dirk Pette
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Phosphorylation of MCPH1 isoforms during mitosis followed by isoform‐specific degradation by APC/C‐CDH1 [PDF]
, 2019 Microcephalin‐1 (MCPH1) exists as 2 isoforms that regulate cyclin‐dependent kinase‐1 activation and chromosome condensation during mitosis, with MCPH1 mutations causing primary microcephaly.
Blain, Peter G. +5 more
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The carbohydrates of the isoforms of three avian riboflavin‐binding proteins [PDF]
European Journal of Biochemistry, 1999 The carbohydrate chains of nine isoforms of chicken egg‐white riboflavin‐binding protein (RfBP) and six isoforms each of quail egg‐white and yolk RfBP have been structurally characterized. The two N‐glycosylation sites, Asn36 and Asn147, of the most abundant isoform of each of the three proteins were analyzed in further detail leading to the ...
A. Amoresano +5 more
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Rat Monoclonal Antibodies Specific for LST1 Proteins [PDF]
, 2009 The LST1 gene is located in the human MHC class III region and encodes transmembrane and soluble isoforms that have been suggested to play a role in the regulation of the immune response and are associated with inflammatory diseases such as rheumatoid ...
Kremmer, Elisabeth +4 more
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Trafficking of the cellular isoform of the prion protein
Biomedicine & Pharmacotherapy, 1999 Transmissible spongiform encephalopathies form a group of fatal neurodegenerative disorders that have the unique property of being infectious, sporadic or genetic in origin. Although the nature of the responsible agent of these diseases is uncertain, it is clear that a protein called PrPSc has a central role in their pathology.
Alain Mangé +2 more
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Arginyltransferase, Its Specificity, Putative Substrates, Bidirectional Promoter, and Splicing-derived Isoforms [PDF]
, 2006 Substrates of the N-end rule pathway include proteins with destabilizing N-terminal residues. Three of them, Asp, Glu, and (oxidized) Cys, function through their conjugation to Arg, one of destabilizing N-terminal residues that are recognized directly by
Brower, Christopher S. +7 more
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Protein Binding to mRNA 3′ Isoforms
Current Protocols in Molecular Biology, 2019 AbstractHere we describe CLIP‐READS, a technique that combines elements of crosslinking and immunoprecipitation (CLIP) and 3′ region extraction and deep sequencing (READS), to provide a genome‐wide map of mRNA 3′ isoform binding by a given messenger ribonucleoprotein (mRNP). In CLIP‐READS, cells are grown to logarithmic phase and are irradiated with UV
Zarmik Moqtaderi, Joseph V. Geisberg
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Agrin isoforms and their role in synaptogenesis [PDF]
, 1992 Agrin is thought to mediate the motor neuron-induced aggregation of synaptic proteins on the surface of muscle fibers at neuromuscular junctions. Recent experiments provide direct evidence in support of this hypothesis, reveal the nature of agrin ...
Escher, Gérard +6 more
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Isoforms of contractile proteins
Progress in Biophysics and Molecular Biology, 1987 Although the mechanism of muscle contraction is essentially the same and the properties ofindividuai contractile proteins such as molecular mass and the overall structure are similar in different types of muscles, more subtle differences were found when muscles of different sources were investigated by using specific and sensitive biochemical ...
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Detecting p53 Isoforms at Protein Level
, 2012 The human p53 protein isoforms are expressed in several cell lines and modulate p53 tumor suppressor -activity, mainly through modulation of gene expression (1-4). Thus, identifying the pattern of p53 isoforms expression in cell lines is a key step for future studies of the p53 network (5).
Marcel, Virginie +5 more
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