Results 31 to 40 of about 6,367,317 (393)
In vivo imaging of the tonoplast intrinsic protein family in Arabidopsis roots [PDF]
, 2009 Background: Tonoplast intrinsic proteins (TIPs) are widely used as markers for vacuolar compartments in higher plants. Ten TIP isoforms are encoded by the Arabidopsis genome.
Frigerio, Lorenzo +4 more
core +4 more sources
Structure-guided isoform identification for the human transcriptome
eLife, 2022 Recently developed methods to predict three-dimensional protein structure with high accuracy have opened new avenues for genome and proteome research. We explore a new hypothesis in genome annotation, namely whether computationally predicted structures ...
Markus J Sommer +8 more
doaj +1 more source
Backbone chemical shift assignments of human 14-3-3$\sigma$ [PDF]
, 2019 14-3-3 proteins are a group of seven dimeric adapter proteins that exert their biological function by interacting with hundreds of phosphorylated proteins, thus influencing their sub-cellular localization, activity or stability in the cell.
Boll, Emmanuelle +5 more
core +3 more sources
Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G [PDF]
, 2009 Background: The activating immunoreceptor NKG2D is expressed on Natural Killer (NK) cells and subsets of T cells. NKG2D contributes to anti-tumour and anti-viral immune responses in vitro and in vivo. The ligands for NKG2D in humans are diverse proteins
A Cerwenka +67 more
core +12 more sources
Arginyltransferase, Its Specificity, Putative Substrates, Bidirectional Promoter, and Splicing-derived Isoforms [PDF]
, 2006 Substrates of the N-end rule pathway include proteins with destabilizing N-terminal residues. Three of them, Asp, Glu, and (oxidized) Cys, function through their conjugation to Arg, one of destabilizing N-terminal residues that are recognized directly by
Brower, Christopher S. +7 more
core +2 more sources
Protein Kinase Cβ Isoform Inhibitors [PDF]
Circulation, 2004 The center of the pandemic of diabetes is the life-threatening cardiovascular complications that can be categorized into macrovasculopathy, microvasculopathy, and diabetic cardiomyopathy. Macrovasculopathy affects large vessels and manifests as atherosclerosis and the subsequent coronary artery disease, peripheral artery disease, and cerebrovascular ...
Zhiheng He, George L. King
openaire +1 more source
Neoplasia: An International Journal for Oncology Research, 2007 IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. However, it is not known whether
Zongbing You +5 more
doaj +1 more source
Agrin isoforms and their role in synaptogenesis [PDF]
, 1992 Agrin is thought to mediate the motor neuron-induced aggregation of synaptic proteins on the surface of muscle fibers at neuromuscular junctions. Recent experiments provide direct evidence in support of this hypothesis, reveal the nature of agrin ...
Escher, Gérard +6 more
core +1 more source
Protein isoforms. Origin, structure and functions. [PDF]
Biopolymers and Cell, 2017 Many proteins in mammalian organism exist as isoforms. These isoforms can be encoded by different genes or produced by alternative splicing of one gene. Despite rapid instrumental progress in the isoform identification, the reasons for their existence and specific functions remain largely unknown.
openaire +2 more sources
Nucleic Acids Research, 2018 The proper subcellular localization of RNAs and local translational regulation is crucial in highly compartmentalized cells, such as neurons. RNA localization is mediated by specific cis-regulatory elements usually found in mRNA 3'UTRs.
Camilla Ciolli Mattioli +9 more
semanticscholar +1 more source