Results 61 to 70 of about 53,939 (158)

The aggregation tendencies of the signal peptide regions of prone and not prone to aggregate proteins

Biochemistry and Biophysics Reports
Signal peptides are a sequence of peptides located at the N-terminus of proteins and determine the protein secretion pathway and their destinations. The N-region is positively charged and influences the orientation of translocation.
Natalie G. Horgan, Anabela Djurovic-Topalovic, Taiwo A. Ademoye, Jessica S. Fortin   +3 more
doaj   +1 more source

In vivo conformational space and defects of misfolded CFTR variants by covalent protein painting

Nature Communications
In vivo characterization of protein structures and structural changes after perturbation is still a major challenge and has impacted our understanding of the molecular events involved in protein misfolding diseases.
Sandra Pankow, Tom Casimir Bamberger, Salvador Martínez-Bartolomé, Robin Park, John R. Yates   +4 more
doaj   +1 more source

Unraveling the Role of Proteinopathies in Parasitic Infections

Biomedicines
Proteinopathies, characterized by the misfolding, aggregation, and deposition of proteins, are hallmarks of various neurodegenerative and systemic diseases.
Mikołaj Hurła, Damian Pikor, Natalia Banaszek-Hurła, Alicja Drelichowska, Jolanta Dorszewska, Wojciech Kozubski, Elżbieta Kacprzak, Małgorzata Paul   +7 more
doaj   +1 more source

Protein Misfolding Diseases [PDF]

Future Science OA, 2015
openaire   +3 more sources

Characterization of a PNLIP variant identified in Amish pediatric patients with congenital pancreatic lipase deficiency

Journal of Lipid Research
Congenital pancreatic lipase deficiency (CPLD, OMIM #614338) is a rare exocrine pancreatic disorder presenting in late infancy with steatorrhea, fat-soluble vitamin deficiency, and low pancreatic lipase activity.
Grace E. Curry, Nicole L. Bertsch, Tran Quach, Rhonda Anderson, Neel Matiwala, Karlla W. Brigatti, Steven J. Wilhelm, Katie B. Williams, Mark E. Lowe, Zineb Ammous, Xunjun K. Xiao   +10 more
doaj   +1 more source

Correction to “Protein Misfolding Thermodynamics” [PDF]

The Journal of Physical Chemistry Letters, 2019
Md Mozzammel Haque, Richard Bayford
openaire   +2 more sources

Protein misfolding [PDF]

Nature, 2003
openaire   +1 more source

Editorial: Unraveling protein misfolding and innate immunity in neurodegenerative diseases. [PDF]

Front Immunol
Fang Q, Hong Y, Zhu B.
europepmc   +1 more source

An Immuno-Infrared Sensor Detects Preclinical Alzheimer's and Parkinson's Disease by Protein Misfolding. [PDF]

J Phys Chem B
Gerwert G, Mann M, Langenhoff L, Woitzik N, Hubert D, Duman D, Höveler A, Budde S, Simon J, Beyer L, Schuler M, Weber S, Mollenhauer B, Kötting C, Güldenhaupt J, Gerwert K.   +15 more
europepmc   +1 more source

Challenges and limitations in computational prediction of protein misfolding in neurodegenerative diseases. [PDF]

Front Comput Neurosci, 2023
Krokidis MG, Dimitrakopoulos GN, Vrahatis AG, Exarchos TP, Vlamos P.   +4 more
europepmc   +1 more source