Results 1 to 10 of about 340,222 (317)

Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.

PLoS ONE, 2021
In yeast and human cells many of the ribosomal proteins (r-proteins) are required for the stabilisation and productive processing of rRNA precursors. Functional coupling of r-protein assembly with the stabilisation and maturation of subunit precursors ...
Gisela Pöll, Michael Pilsl, Joachim Griesenbeck, Herbert Tschochner, Philipp Milkereit   +4 more
doaj   +2 more sources

Understanding the Effects of Trenbolone Acetate, Polyamine Precursors, and Polyamines on Proliferation, Protein Synthesis Rates, and the Abundance of Genes Involved in Myoblast Growth, Polyamine Biosynthesis, and Protein Synthesis in Murine Myoblasts

Biology, 2023
Research suggests that androgens increase skeletal muscle growth by modulating polyamine biosynthesis. As such, the objective of this study was to investigate effects of anabolic hormones, polyamine precursors, and polyamines relative to proliferation ...
Laura A. Motsinger, Lillian L. Okamoto, Nikole E. Ineck, Brynne A. Udy, Christopher L. Erickson, Youssef Harraq, Caleb C. Reichhardt, Gordon K. Murdoch, Kara Jean Thornton   +8 more
doaj   +1 more source

Chloroplast precursor protein translocon [PDF]

FEBS Letters, 1999
Chloroplasts are believed to have originated from a photosynthetic, prokaryotic ancestor. As the result of endosymbiotic evolution, most of the genes of the endocytobiont were displaced to the host nucleus. Today's chloroplasts must import most of their proteins from the cytosol as precursors.
May, Timo, Soll, Jürgen
openaire   +2 more sources

Enzymes in the Cholesterol Synthesis Pathway: Interactomics in the Cancer Context

Biomedicines, 2021
A global protein interactome ensures the maintenance of regulatory, signaling and structural processes in cells, but at the same time, aberrations in the repertoire of protein–protein interactions usually cause a disease onset.
Pavel Ershov, Leonid Kaluzhskiy, Yuri Mezentsev, Evgeniy Yablokov, Oksana Gnedenko, Alexis Ivanov   +5 more
doaj   +1 more source

Functional requirements for a Samd14-capping protein complex in stress erythropoiesis

eLife, 2022
Acute anemia induces rapid expansion of erythroid precursors and accelerated differentiation to replenish erythrocytes. Paracrine signals—involving cooperation between stem cell factor (SCF)/Kit signaling and other signaling inputs—are required for the ...
Suhita Ray, Linda Chee, Yichao Zhou, Meg A Schaefer, Michael J Naldrett, Sophie Alvarez, Nicholas T Woods, Kyle J Hewitt   +7 more
doaj   +1 more source

In Silico Approach of Glycinin and Conglycinin Chains of Soybean By-Product (Okara) Using Papain and Bromelain

Molecules, 2022
This study explores utilization of a sustainable soybean by-product (okara) based on in silico approach. In silico approaches, as well as the BIOPEP database, PeptideRanker database, Peptide Calculator database (Pepcalc), ToxinPred database, and AllerTop
Andriati Ningrum, Dian Wahyu Wardani, Nurul Vanidia, Achmat Sarifudin, Rima Kumalasari, Riyanti Ekafitri, Dita Kristanti, Woro Setiaboma, Heli Siti Halimatul Munawaroh   +8 more
doaj   +1 more source

Recent Advances in Chemical Biology Using Benzophenones and Diazirines as Radical Precursors

Molecules, 2020
The use of light-activated chemical probes to study biological interactions was first discovered in the 1960s, and has since found many applications in studying diseases and gaining deeper insight into various cellular mechanisms involving protein ...
Muhammad Murtaza Hassan, Olasunkanmi O. Olaoye   +1 more
doaj   +1 more source

Nucleation precursors in protein crystallization [PDF]

Acta Crystallographica Section F Structural Biology Communications, 2014
Protein crystal nucleation is a central problem in biological crystallography and other areas of science, technology and medicine. Recent studies have demonstrated that protein crystal nuclei form within crucial precursors. Here, methods of detection and characterization of the precursors are reviewed: dynamic light scattering, atomic force microscopy ...
Peter G, Vekilov, Maria A, Vorontsova
openaire   +2 more sources

RECOMBINANT PROTEIN OF VARIOLA VIRUS ABOLISHES THE EFFECTS OF TUMOR NECROSIS FACTOR UPON MARROW HEMATOPOIESIS IN BALB/С MICE

Медицинская иммунология, 2014
We studied the effect of a recombinant murine TNF (rmTNF) and TNF-binding protein of Variola virus (VARV-CrmB) upon colony-forming ability of bone marrow cells (BMC) from Balb/c mice.
L. B. Toporkova, A. A. Petuhova, I. P. Gileva, I. A. Orlovskaya   +3 more
doaj   +1 more source

Neuroprotective Secreted Amyloid Precursor Protein Acts by Disrupting Amyloid Precursor Protein Dimers [PDF]

Journal of Biological Chemistry, 2009
The amyloid precursor protein (APP) is implied both in cell growth and differentiation and in neurodegenerative processes in Alzheimer disease. Regulated proteolysis of APP generates biologically active fragments such as the neuroprotective secreted ectodomain sAPPalpha and the neurotoxic beta-amyloid peptide.
Gralle, M. ; https://orcid.org/0000-0002-0472-4263, Gralle Botelho, M., Wouters, F.   +2 more
openaire   +5 more sources