Results 121 to 130 of about 40,533 (205)

Issue Information

mLife, Volume 5, Issue 2, Page i-iv, April 2026.
wiley   +1 more source

Geranylgeranyl isoprenoids and hepatic Rap1a regulate basal and statin-induced expression of PCSK9

Journal of Lipid Research
LDL-C lowering is the main goal of atherosclerotic cardiovascular disease prevention, and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition is now a validated therapeutic strategy that lowers serum LDL-C and reduces coronary events ...
Yating Wang, Brea Tinsley, Stefano Spolitu, John A. Zadroga, Heena Agarwal, Amesh K. Sarecha, Lale Ozcan   +6 more
doaj   +1 more source

Methyl-Jasmonate Functions as a Molecular Switch Promoting Cross-Talk between Pathways for the Biosynthesis of Isoprenoid Backbones Used to Modify Proteins in Plants

Plants
In plants, the plastidial mevalonate (MVA)-independent pathway is required for the modification with geranylgeranyl groups of CaaL-motif proteins, which are substrates of protein geranylgeranyltransferase type-I (PGGT-I).
Quentin Chevalier, Alexandre Huchelmann, Pauline Debié, Pierre Mercier, Michael Hartmann, Catherine Vonthron-Sénécheau, Thomas J. Bach, Hubert Schaller, Andréa Hemmerlin   +8 more
doaj   +1 more source

Probes for protein prenylation [PDF]

Nature Methods, 2019
openaire   +2 more sources

Internal mammary artery smooth muscle cells resist migration and possess high antioxidant capacity [PDF]

, 2006
Objective- This study investigated whether differences exist in atherogen-induced migratory behaviors and basal antioxidant enzyme capacity of vascular smooth muscle cells (VSMC) from human coronary (CA) and internal mammary (IMA) arteries.
Bayraktutan, Ulvi, Campbell, Malcolm, Mahadevan, Vaikom, McKeown, Pascal   +3 more
core  

Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector T_reg Cells. [PDF]

Cell Metab, 2020
Su W, Chapman NM, Wei J, Zeng H, Dhungana Y, Shi H, Saravia J, Zhou P, Long L, Rankin S, Kc A, Vogel P, Chi H.   +12 more
europepmc   +1 more source

Metformin Suppresses Cancer Stem Cells through AMPK Activation and Inhibition of Protein Prenylation of the Mevalonate Pathway in Colorectal Cancer. [PDF]

Cancers (Basel), 2020
Seo Y, Kim J, Park SJ, Park JJ, Cheon JH, Kim WH, Kim TI.   +6 more
europepmc   +1 more source

Systems biology strategy for drug potentiating through drug repurposing:bisphosphonates beyond osteoporosis treatment [PDF]

, 2018
Goltsov, Alexey, Kowalczyk, Zuzanna, Papineni, Rao V. L.   +2 more
core   +2 more sources

Novel benzimidazole phosphonates as potential inhibitors of protein prenylation. [PDF]

Bioorg Med Chem Lett, 2019
Bhuiyan NH, Varney ML, Wiemer DF, Holstein SA.   +3 more
europepmc   +1 more source

Protein Prenylation Makeovers in Plants: Insights into Substrate Diversification. [PDF]

Int J Mol Sci
Chevalier Q, Debié P, Huchelmann A, Hemmerlin A.   +3 more
europepmc   +1 more source