Results 101 to 110 of about 40,533 (205)

Pathogenesis of Adenomyosis: An Integrated Review of Cellular Origins, Molecular Mechanisms, and Intersecting Diseases

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Adenomyosis is a prevalent disorder of the archimetra, historically conflated with endometriosis but possessing a unique pathobiological trajectory. This review synthesises current molecular evidence to propose a unified mechanistic framework initiated by tissue injury and repair (TIAR), aberrant stem cell activation, or de novo metaplasia ...
Jiang Yang, Xiaochong Li, Yu Peng, Zhongfeng Sun, Lingli Zhang, Jie Duan, Nanbert Zhong   +6 more
wiley   +1 more source

Fats and function:protein lipid modifications in plant cell signalling [PDF]

, 2017
The post-translational lipid modifications N-myristoylation, prenylation and S-acylation are traditionally associated with increasing protein membrane affinity.
Adjobo-Hermans, Alassimone, Assmann, Batistic, Batistic, Bischoff, Boisson, Bücherl, Couto, de Vries, Dionne Turnbull, Goldberg, Grison, Hemsley, Hemsley, Hemsley, Heo, Kapos, Koh, Konrad, Kumar, Kummel, Lai, Lavy, Li, Liu, Malinsky, Matsui, Meng, Morozova, Nimchuk, Noland, Pierre, Piers A Hemsley, Qi, Qi, Qi, Ranf, Renna, Resh, Running, Running, Ryan, Schiefelbein, Sorek, Sorek, Sorek, Srivastava, Stangl, Takahashi, Thole, Traverso, Zeng, Zhang, Zhou   +54 more
core   +2 more sources

Resurrected Ancestral Cannabis Enzymes Unveil the Origin and Functional Evolution of Cannabinoid Synthases

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2685-2697, April 2026.
ABSTRACT Cannabinoids, such as tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA) and cannabichromenic acid (CBCA), are bioactive and medicinally relevant compounds found in the cannabis plant (Cannabis sativa L.). These three compounds are synthesised from a single precursor, cannabigerolic acid (CBGA), through regioselective reactions ...
Cloé Villard, Idil Baser, Arjen C. van de Peppel, Katarina Cankar, M. Eric Schranz, Robin van Velzen   +5 more
wiley   +1 more source

The ubiK protein is an accessory factor necessary for bacterial Ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ [PDF]

, 2017
Ubiquinone (UQ), also referred to as coenzyme Q, is a widespread lipophilic molecule in both prokaryotes and eukaryotes in which it primarily acts as an electron carrier.
Aussel, Laurent, Barras, Frédéric, Casadesús Pursals, Josep, Chehade, Mahmoud Hajj, Faivre, Bruno, Fyfe, Cameron David, Hernández Piñero, Sara Belén, Loiseau, Laurent   +7 more
core   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, Volume 13, Issue 18, 27 March 2026.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

Potato mop-top virus co-opts the stress sensor HIPP26 for long-distance movement [PDF]

, 2018
The work of LT, GC, SJ and AR is funded by the Scottish Government’s Rural and Environmental Science and Analytical Services (RESAS) Division, PH by the BBSRC (grant BB/M024911/1) and The Royal Society and EIS by the Swedish Research Council Formas and ...
Cowan, Graham H., Gil, Jose F., Hemsley, Piers, Jones, Susan, Kalyandurg, Pruthvi B., Kumar, Pankaj, Roberts, Alison G., Savenkov, Eugene I, Torrance, Lesley   +8 more
core   +4 more sources

Pan‐Modification Proteoformics: A Framework for Decoding Proteomic Complexity in Health and Disease

Barrier Immunity, Volume 2, Issue 1, Page 32-49, March 2026.
Post‐translational modification (PTM) diversity represents a central regulatory layer that drives protein functional complexity. Classical PTMs (phosphorylation, acetylation, ubiquitination, and glycosylation) and emerging PTMs (SUMOylation, lipidation, and ADP‐ribosylation) form dynamic modification codes that govern signaling, metabolism, and ...
Yang Yang, Wenzhi Guo, Jing‐Hua Yang
wiley   +1 more source

Tackling resistance: Emerging antimalarials and new parasite targets in the era of elimination [version 1; referees: 2 approved] [PDF]

, 2018
Malaria remains a significant contributor to global human mortality, and roughly half the world’s population is at risk for infection with Plasmodium spp. parasites.
Matthews, Emily S, Odom John, Audrey R
core   +2 more sources

Thematic review series: Lipid Posttranslational Modifications. Geranylgeranylation of Rab GTPases

Journal of Lipid Research, 2006
Rab GTPases require special machinery for protein prenylation, which include Rab escort protein (REP) and Rab geranylgeranyl transferase (RGGT). The current model of Rab geranylgeranylation proposes that REP binds Rab and presents it to RGGT.
Ka Fai Leung, Rudi Baron, Miguel C. Seabra   +2 more
doaj   +1 more source

GGPPS1 predicts the biological character of hepatocellular carcinoma in patients with cirrhosis [PDF]

, 2014
Background: Hepatocellular carcinoma (HCC) has been associated with diabetes and obesity, but a possible connection with the metabolic syndrome (MetS) and its potential interaction with hepatitis and cirrhosis are open to discussion.
Chen, Jun, Ding, Yi-tao, Li, Chao-jun, Liu, Jia, Shao, Jiao-jiao, Shen, Xiao, Xia, Hong-guang, Xue, Bin, Yu, De-cai   +8 more
core   +1 more source