Results 31 to 40 of about 19,078,260 (300)
, 2021 Quality control is changing along with the manufacturing environment. A series of revolutionary changes will occur in management contents, methods, capabilities, and real-time effectiveness and efficiency of management.
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Frontiers in Cellular and Infection Microbiology, 2023 IntroductionDental caries is one of the most common and costly biofilm-dependent oral diseases in the world. Streptococcus mutans is the major cariogenic pathogen of dental caries. S.
Shuwei Liu +10 more
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The protein quality control and neurodegeneration
Folia Pharmacologica Japonica, 2003 There are growing lines of evidence addressing a potential link between failure of protein quality control and neurodegeneration. Hence, it is important to know the quality control mechanism of the cell for understanding the molecular basis underlying neurodegenerative diseases.
TANAKA, Keiji, MURATA, Shigeo
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Protein quality control in the endoplasmic reticulum
Current Opinion in Cell Biology, 2020 Misfolded and mistargeted proteins in the early secretory pathway present significant risks to the cell. A diverse and integrated network of quality control pathways protects the cell from these threats. We focus on the discovery of new mechanisms that contribute to this protective network.
Phillips, Ben P. +2 more
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USP5 enhances SGTA mediated protein quality control.
PLoS ONE, 2022 Mislocalised membrane proteins (MLPs) present a risk to the cell due to exposed hydrophobic amino acids which cause MLPs to aggregate. Previous studies identified SGTA as a key component of the machinery that regulates the quality control of MLPs ...
Jake Hill, Yvonne Nyathi
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Fishes, 2022 Acute hepatopancreatic necrosis disease (AHPND) caused by Vibrio parahaemolyticus (VpAHPND) has been reported in commodity shrimp, but the potential risk of its global spread via frozen shrimp in the shrimp trade is yet to be fully explored.
Chorong Lee +7 more
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Quality control of overexpressed membrane proteins [PDF]
Proceedings of the National Academy of Sciences, 2008 Overexpression of membrane proteins in Escherichia coli frequently leads to the formation of aggregates or inclusion bodies, which is undesirable for most studies. Ideally, one would like to optimize the expression conditions by monitoring simultaneously and rapidly both the amounts of ...
Geertsma, Eric R. +3 more
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SGTA regulates the cytosolic quality control of hydrophobic substrates [PDF]
, 2014 Hydrophobic amino acids are normally shielded from the cytosol and their exposure is often used as an indicator of protein misfolding to enable the chaperone-mediated recognition and quality control of aberrant polypeptides.
Payapilly, Aishwarya +4 more
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Protein quality control of N-methyl-D-aspartate receptors
Frontiers in Cellular Neuroscience, 2022 N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated cation channels that mediate excitatory neurotransmission and are critical for synaptic development and plasticity in the mammalian central nervous system (CNS). Functional NMDARs typically form
Taylor M. Benske +2 more
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Membrane protein folding and quality control
Current Opinion in Structural Biology, 2021 Membrane proteins account for a quarter of cellular proteins, and most are synthesised at the endoplasmic reticulum (ER). Insertion and folding of polypeptides in the membrane environment is prone to error, necessitating diverse quality control systems.
Ben P. Phillips, Elizabeth A. Miller
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