Results 31 to 40 of about 22,982,554 (304)

Mitochondrial complexome reveals quality-control pathways of protein import

open access: yesNature, 2023
Mitochondria have crucial roles in cellular energetics, metabolism, signalling and quality control^ 1 – 4 . They contain around 1,000 different proteins that often assemble into complexes and supercomplexes such as respiratory complexes and preprotein ...
U. Schulte   +19 more
semanticscholar   +1 more source

Charactering the spoilage mechanism of “three sticks” of Jinhua ham

open access: yesFood Science and Human Wellness, 2022
To investigate the spoilage characteristics of Jinhua ham, sensory scores, volatile compounds, biogenic amine, physicochemical parameters and microbial counts were evaluated between normal and spoiled hams.
Changyu Zhou   +6 more
doaj   +1 more source

Ubiquitin-proteasome dependent mitochondrial protein quality control [PDF]

open access: yes, 2014
Dysfunctional mitochondria cause many neurodegenerative disorders and with aging in general, mechanisms of mitochondrial quality control are essential for cellular function.
Benischke, Anne-Sophie
core   +1 more source

How do protein aggregates escape quality control in neurodegeneration? [PDF]

open access: yes, 2022
Protein aggregates are hallmarks of neurodegenerative diseases. The protein quality control (PQC) system normally prevents proteins from misfolding and accumulation; however, proteins somehow escape this control on disease. Here we review advances in the
Ferrari, Luca   +4 more
core  

Antibacterial mechanism of areca nut essential oils against Streptococcus mutans by targeting the biofilm and the cell membrane

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionDental caries is one of the most common and costly biofilm-dependent oral diseases in the world. Streptococcus mutans is the major cariogenic pathogen of dental caries. S.
Shuwei Liu   +10 more
doaj   +1 more source

Protein Quality Control and Lipid Droplet Metabolism

open access: yesAnnual Review of Cell and Developmental Biology, 2020
Lipid droplets (LDs) are endoplasmic reticulum–derived organelles that consist of a core of neutral lipids encircled by a phospholipid monolayer decorated with proteins.
Melissa A. Roberts, James A. Olzmann
semanticscholar   +1 more source

Reshaping Endoplasmic Reticulum Quality Control Through the Unfolded Protein Response

open access: yesMolecules and Cells, 2022
SUMMARY Endoplasmic reticulum quality control (ERQC) pathways comprised of chaperones, folding enzymes, and degradation factors ensure the fidelity of ER protein folding and trafficking to downstream secretory environments.
R. Wiseman   +2 more
semanticscholar   +1 more source

SGTA regulates the cytosolic quality control of hydrophobic substrates [PDF]

open access: yes, 2014
Hydrophobic amino acids are normally shielded from the cytosol and their exposure is often used as an indicator of protein misfolding to enable the chaperone-mediated recognition and quality control of aberrant polypeptides.
Payapilly, Aishwarya   +4 more
core   +1 more source

USP5 enhances SGTA mediated protein quality control.

open access: yesPLoS ONE, 2022
Mislocalised membrane proteins (MLPs) present a risk to the cell due to exposed hydrophobic amino acids which cause MLPs to aggregate. Previous studies identified SGTA as a key component of the machinery that regulates the quality control of MLPs ...
Jake Hill, Yvonne Nyathi
doaj   +3 more sources

Infectivity and Transmissibility of Acute Hepatopancreatic Necrosis Disease Associated Vibrio parahaemolyticus in Frozen Shrimp Archived at −80 °C

open access: yesFishes, 2022
Acute hepatopancreatic necrosis disease (AHPND) caused by Vibrio parahaemolyticus (VpAHPND) has been reported in commodity shrimp, but the potential risk of its global spread via frozen shrimp in the shrimp trade is yet to be fully explored.
Chorong Lee   +7 more
doaj   +1 more source

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