Results 41 to 50 of about 56,029 (251)

Dynamic Characterization of Protein and Posttranslational Modification Levels in Mycobacterial Cholesterol Catabolism

mSystems, 2020
Cholesterol of the host macrophage membrane is vital for mycobacterial infection, replication, and persistence. During chronic infection within host lung tissues, cholesterol facilitates the phagocytosis of mycobacteria into macrophages.
Jun-Yu Xu, Lei Zhao, Ying Xu, Bolin Li, Linhui Zhai, Minjia Tan, Bang-Ce Ye   +6 more
doaj   +3 more sources

Protein S-acylation: Pathological mechanisms and novel therapeutic targets for diabetic complications. [PDF]

Chin Herb Med
Liu R, Xu N, Song X, Li Y, Bu J, Su R, Guo H, Jiang C, Zhuang P, Zhang Y, Yin Q.   +10 more
europepmc   +2 more sources

Influence of soy protein’s structural modifications on their microencapsulation properties: a-tocopherol microparticles preparation [PDF]

, 2012
Enzymatic and chemical modifications of soy protein isolate (SPI) were studied in order to improve SPI properties for their use as wall material for a-tocopherol microencapsulation by spray-drying.
Alric, Isabelle, Durrieu, Vanessa, Nesterenko, Alla, Silvestre, Françoise   +3 more
core   +1 more source

Green Production of Anionic Surfactant Obtained from Pea Protein [PDF]

, 2011
A pea protein isolate was hydrolyzed by a double enzyme treatment method in order to obtain short peptide sequences used as raw materials to produce lipopeptides-based surfactants.
A Clemente, A Tsoukala, A Villanueva, AF Dexter, Bénédicte Portet, C Megias, C Rondel, Caroline Rondel, CN Mulligan, D Kitamoto, EA Pena-Ramos, FM Netto, Françoise Silvestre, H Frister, H Schägger, Isabelle Alric, J Vioque, Jean-François Blanco, JS Hamada, JY Lee, K Pommer, K Yasamatsu, LA Graaf De, LM Humiski, M Dall Aaslyng, M Karamac, M Le Gall, MC Marquez, MPC Silvestre, MR Infante, P Anastas, PM Nielsen, R Amarowicz, R Sanchez-Vioque, R Sanchez-Vioque, R Sinha, RT Swank, S Jung, TS Padmashree, UK Laemmli, Zéphirin Mouloungui   +40 more
core   +2 more sources

Polyglutamine Tract Expansion Increases S-Nitrosylation of Huntingtin and Ataxin-1. [PDF]

PLoS ONE, 2016
Expansion of the polyglutamine (polyQ) tract in the huntingtin (Htt) protein causes Huntington's disease (HD), a fatal inherited movement disorder linked to neurodegeneration in the striatum and cortex.
Chun-Lun Ni, Divya Seth, Fabio Vasconcelos Fonseca, Liwen Wang, Tsan Sam Xiao, Phillip Gruber, Man-Sun Sy, Jonathan S Stamler, Alan M Tartakoff   +8 more
doaj   +1 more source

A novel yeast-based high-throughput method for the identification of protein palmitoylation inhibitors

Open Biology, 2021
Protein S-acylation or palmitoylation is a widespread post-translational modification that consists of the addition of a lipid molecule to cysteine residues of proteins through a thioester bond.
Consuelo Coronel Arrechea, María Luz Giolito, Iris Alejandra García, Gastón Soria, Javier Valdez Taubas   +4 more
doaj   +1 more source

ATP-independent Control of Vac8 Palmitoylation by a SNARE Subcomplex on Yeast Vacuoles [PDF]

, 2005
Yeast vacuole fusion requires palmitoylated Vac8. We previously showed that Vac8 acylation occurs early in the fusion reaction, is blocked by antibodies against Sec18 (yeast N-ethylmaleimide-sensitive fusion protein (NSF)), and is mediated by the R-SNARE
Cristodero, Marina, Dietrich, Lars E. P., LaGrassa, Tracy J., Meiringer, Christoph T. A., Rohde, Jan, Ungermann, Christian   +5 more
core   +1 more source

Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution

Cell Reports, 2021
Summary: In addition to acetylation, histones are modified by a series of competing longer-chain acylations. Most of these acylation marks are enriched and co-exist with acetylation on active gene regulatory elements.
Mengqing Gao, Jin Wang, Sophie Rousseaux, Minjia Tan, Lulu Pan, Lijun Peng, Sisi Wang, Wenqian Xu, Jiayi Ren, Yuanfang Liu, Martin Spinck, Sophie Barral, Tao Wang, Florent Chuffart, Ekaterina Bourova-Flin, Denis Puthier, Sandrine Curtet, Lisa Bargier, Zhongyi Cheng, Heinz Neumann, Jian Li, Yingming Zhao, Jian-Qing Mi, Saadi Khochbin   +23 more
doaj   +1 more source

S-acylation dependent post-translational cross-talk regulates large conductance calcium- and voltage- activated potassium (BK) channels

Frontiers in Physiology, 2014
Mechanisms that control surface expression and/or activity of large conductance calcium-activated potassium (BK) channels are important determinants of their (patho)physiological function.
Michael J Shipston
doaj   +1 more source

Lost in traffic: consequences of altered palmitoylation in neurodegeneration

Frontiers in Physiology, 2023
One of the first molecular events in neurodegenerative diseases, regardless of etiology, is protein mislocalization. Protein mislocalization in neurons is often linked to proteostasis deficiencies leading to the build-up of misfolded proteins and/or ...
Firyal Ramzan, Fatima Abrar, Gyana Gourab Mishra, Lucia Meng Qi Liao, Dale D. O. Martin   +4 more
doaj   +1 more source