Results 71 to 80 of about 80,473 (260)

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

open access: yesAdvanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan   +24 more
wiley   +1 more source

Atherosclerosis in perlecan heterozygous mice

open access: yesJournal of Lipid Research, 2004
The hypothesis that lipoprotein association with perlecan is atherogenic was tested by studying atherosclerosis in mice that had a heterozygous deletion of perlecan, the primary extracellular heparan sulfate proteoglycan in arteries. We first studied the
Reeba K. Vikramadithyan   +6 more
doaj   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

open access: yesAdvanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Heparan sulfate and control of cell division: adhesion and proliferation of mutant CHO-745 cells lacking xylosyl transferase

open access: yesBrazilian Journal of Medical and Biological Research, 2001
We have examined the role of cell surface glycosaminoglycans in cell division: adhesion and proliferation of Chinese hamster ovary (CHO) cells.
C.R.C. Franco   +7 more
doaj   +1 more source

Mechanisms of Pericyte‐Mediated Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

Editorial: Molecules of the extracellular matrix as cancer targets

open access: yesFrontiers in Oncology, 2022
Nikos K. Karamanos   +2 more
doaj   +1 more source

A preliminary study of the effects of glucosamine sulphate and chondroitin sulphate on surgically treated and untreated focal cartilage damage [PDF]

open access: yesEuropean Cells & Materials, 2011
The effects of Glucosamine Sulphate (GS) and Chondroitin Sulphate (CS) on the healing of damaged and repaired articular cartilage were investigated. This study was conducted using 18 New Zealand white rabbits as experimental models.
T Kamarul   +4 more
doaj  

BIOCHEMICAL INDICATORS OF CONNECTIVE TISSUE IN RAT PERIODONTIUM IN LOCAL GUM DAMAGE UNDER LIPOPOLISACHARIDE-INDUCED SYSTEMIC INFLAMMATORY RESPONSE

open access: yesŽurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
Objectives: To assess the biochemical indicators of the connective tissue of rat periodontium (collagen, proteoglycans, glycoproteins) in local gum damage associated with lipopolysaccharide-induced systemic inflammatory response (SIR).
Yelinskaya A. N.   +2 more
doaj   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Melanocyte Transformation Associated with Substrate Adhesion Impediment

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
Exclude experimental models of malignant transformation employ chemical and physical carcinogens or genetic manipulations to study tumor progression.
Sueli M. Oba-Shinjo   +10 more
doaj   +1 more source

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