Results 181 to 190 of about 57,493 (305)

Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms

British Journal of Pharmacology, EarlyView.
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl, Jakub Morze, Sabina Wallerer, Georg Hoffmann   +3 more
wiley   +1 more source

A special issue of Essays in Biochemistry on proteasome and protein degradation. [PDF]

Essays Biochem
Sahu I, Glickman MH.
europepmc   +1 more source

Atezolizumab + Chemotherapy in Older Patients With Lung Cancer in Japan

Cancer Science, EarlyView.
OS (A–D) and PFS (E–H) in patients receiving (A/E) Atezo + CnP, (B/F) Atezo + PP, (C/G) Atezo + bev + CP, and (D/H) Atezo + CEa by age (≥ 70 years and < 70 years). aSaito R, et al. Presented at the 2024 American Society of Clinical Oncology Annual Meeting. Abstract 8092. Adapted with permission by the author.
Junichi Shimizu, Makoto Nishio, Kadoaki Ohashi, Atsushi Osoegawa, Eiki Kikuchi, Hideharu Kimura, Yasushi Goto, Eisaku Miyauchi, Hiroshige Yoshioka, Ichiro Yoshino, Toshihiro Misumi, Kozo Yoshimori, Kazuhiko Shibata, Takeshi Tsuda, Masahiro Seike, Takahiro Ota, Koichi Samata, Yuki Kobayashi, Misa Tanaka, Akihiko Gemma   +19 more
wiley   +1 more source

The α-synuclein proteostasis network and its translational applications in Parkinson's disease. [PDF]

Proc Natl Acad Sci U S A
Lim CM, Vendruscolo M.
europepmc   +1 more source

The endoplasmic reticulum in mitochondrial protein targeting: A neuronal perspective on organelle crosstalk. [PDF]

Protein Sci
Hees JT, Harbauer AB.
europepmc   +1 more source

Proteostasis Therapeutics [PDF]

Nature Biotechnology, 2009
openaire   +1 more source

Roles of ER Membrane Protein Complex in Protein Biogenesis and Quality Control in the Lung and Beyond

Cell Proliferation, EarlyView.
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao, Yuqing Sun, Yutao Huang, Qinghang Meng, Xinhua Lin, Wei Wei, Xiaofang Tang   +6 more
wiley   +1 more source

Heat shock proteins (Hsp70 and Hsp90) in neurodegeneration: pathogenic roles and therapeutic potential. [PDF]

Front Aging Neurosci
Ben Khalaf N.
europepmc   +1 more source

Heat Stress Triggers Nuclear Invagination and Spatial Compartmentalization of Protein Metabolism

Cell Proliferation, EarlyView.
Cells adapt heat stress to shape a nuclear invagination region function as “protein metabolism hotspots”, where both protein production and degradation are enhanced. ABSTRACT Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the highly conserved mechanism known as
Zhi‐Hao Zhang, Yuan‐Tao Qiu, Jing‐Yue Cao, Yi‐Feng Huang, Ye‐Lin Lan, Yu‐Li Zhao, Fu Wu, Chen‐Long Wang, Guo‐Run Tang, Jing‐Yun Ji, Zhang Zhang, Guan‐Zheng Luo   +11 more
wiley   +1 more source

Functional interplay between heat shock protein 90 (HSP90) and heat shock factors (HSFs). [PDF]

Cell Stress Chaperones
Chakraborty A, Sistonen L, Roos-Mattjus P.   +2 more
europepmc   +1 more source