Results 181 to 190 of about 48,911 (292)

Redox regulation of PDE6 and cGMP signaling in diabetic retinal neurodegeneration. [PDF]

Biochem Biophys Rep
Perez-Martinez CJ, Lewis-Luján LM, Cota-Arrayales CA, Guerrero-Magaña DE, Vargas-Durazo JT, Trushin MV, Osadchuk MA, Iloki-Lewis AP, Galvez-Ruiz JC, Iloki-Assanga SB.   +9 more
europepmc   +1 more source

A Biomimetic Breast Tumor‐On‐Chip Platform Reveals Mesenchymal Marker Upregulation Following Gold Nanorod Photothermal Therapy

Small, EarlyView.
A biomimetic microfluidic tumor‐on‐chip platform was designed to uncover subtype‐dependent responses to nanoparticle‐mediated photothermal therapy in breast cancer spheroids. The platform establishes a physiologically relevant and controllable 3D system for precision evaluation of nanophotothermal cancer therapies.
Camila A. Salvego, Hasti Honari, Anastasiia Dubrova, Stéphanie Descroix, Martha S. Ribeiro, Aurore V. Walle, Claire Wilhelm   +6 more
wiley   +1 more source

Circular RNAs-Stress Granule Interplay Drives Aging-Related Proteostasis Loss. [PDF]

Aging Cell
Izquierdo JM.
europepmc   +1 more source

HSPE1 deficiency underlies the crosstalk between metabolic dysfunction‐associated steatotic liver disease and age‐related macular degeneration

VIEW, EarlyView.
Rare‐earth ions act as multifunctional modifiers in perovskite solar cells by improving charge transport, suppressing oxygen vacancies, passivating defects, promoting grain growth, and enabling redox‐mediated stabilization. In addition, RE‐doped layers can expand spectral utilization through upconversion and downconversion, thereby enhancing light ...
Jiaqi Meng, Alimire Maihemuti, Yuan Yuan, Chao Chen, Mengchao Zhu, Hao Wang, Furong Zhu, Zhaodi Che, Jia Xiao, Xiangjia Zhu   +9 more
wiley   +1 more source

From Proteinopathy to Immunopathy in Alzheimer's Disease-A Role for Astrocytic Calcineurin? [PDF]

J Neurochem
Lim D, Tapella L.
europepmc   +1 more source

Proteostasis Therapeutics [PDF]

Nature Biotechnology, 2009
openaire   +1 more source

Zn2+‐Driven Self‐Amplifying Nanoplatform Enables Cascade Photothermal–Gene Therapy via Mitochondrial Disruption

VIEW, EarlyView.
A Zn2+‐activated nanoplatform enables self‐amplifying photothermal–gene therapy by disrupting mitochondria and releasing siRNA, creating a feedback loop that sensitizes tumor cells and enhances ablation in vitro and in vivo. This metal ion‐driven strategy offers a new approach for cascade‐amplified nanotherapeutics. ABSTRACT The therapeutic efficacy of
Zhi Li, Yuhong Chen, Youfei Zhang, Luzhen Huai, Xingzhou Zhu, Xue Mo, Jiahao Wang, Kui Zeng, Jie Wang   +8 more
wiley   +1 more source

COG7 links Golgi integrity to stress signaling and senescence. [PDF]

Plant J
Gómez-Méndez MF, Oseguera Y, Oseguera G, Guo J, Wu R, Inskeep T, Wang J, Choi H, Dehesh K.   +8 more
europepmc   +1 more source

Comparative Genomics and Functional Evidence for Convergent Adaptation to Hypoxia in Mammals

Integrative Zoology, EarlyView.
This study reveals convergent selection in mammals adapted to hypoxia. Functional assays demonstrate that amino acid mutations reduce oxidative stress, attenuate hypoxia‐induced injury, and modulate the hypoxia‐inducible transcription factor (HIF)‐driven hypoxic response.
Hao Dong, Chunxu Wang, Enqing Pei, Liang Zhao, Simin Chai, Ran Tian   +5 more
wiley   +1 more source

Public cohort analysis identifies thyroglobulin variants as hypothyroidism risk factors. [PDF]

J Biol Chem
Hermanson JN, Hudson AD, Plate L.
europepmc   +1 more source