Results 1 to 10 of about 174,020 (338)

Identification of Prothrombin Belgrade Variant in a Mexican–American Family with Recurrent Deep Vein Thrombosis [PDF]

open access: yesTH Open
A rare prothrombin variant (c.1787G > A, p.Arg596Gln), also known as the prothrombin Belgrade variant, has been associated with an increased predisposition to thrombosis through resistance to antithrombin.
Émile Moura Coelho da Silva   +2 more
doaj   +2 more sources

Coagulation Status and Surgical Approach as Predictors of Postoperative Anemia in Patients Undergoing Thoracic Surgery: A Retrospective Study

open access: yesFrontiers in Surgery, 2021
Objective: Postoperative anemia is a common complication after a major surgery. Our study aims to identify factors that are associated with higher risk of developing postoperative anemia after thoracic surgery.Methods: We conducted a retrospective study ...
Zhongping Lang, Yue Wu, Minwei Bao
doaj   +1 more source

Antiphospholipid Antibody Assays in 2021: Looking for a Predictive Value in Addition to a Diagnostic One

open access: yesFrontiers in Immunology, 2021
Antiphospholipid antibodies (aPL) are mandatory for the diagnosis but are also a risk factor for the antiphospholipid syndrome (APS) clinical manifestations.
Pier Luigi Meroni   +2 more
doaj   +1 more source

Discovery of Screening Biomarkers for Major Depressive Disorder in Remission by Proteomic Approach

open access: yesDiagnostics, 2021
Major depressive disorder (MDD) is a common disorder involving depressive mood and decreased motivation. Due to its high heterogeneity, novel biomarkers are required to diagnose MDD.
Hyebin Choi   +5 more
doaj   +1 more source

Prothrombin expression in cancer-derived cell lines [PDF]

open access: yesArchives of Biological Sciences, 2019
The link between thrombotic disorders and cancer has been known for over 150 years, although the precise mechanism of this relationship has not yet been resolved.
Dunjić Sofija   +6 more
doaj   +1 more source

Large‐scale screening for factor V Leiden (G1691A), prothrombin (G20210A), and MTHFR (C677T) mutations in Greek population

open access: yesHealth Science Reports, 2022
Background and aims To provide a fair estimate of the prevalence of factor V Leiden (FVL) (G1691A), prothrombin (G20210A), and MTHFR (C677T) mutations in the Greek population.
Alkistis Raptopoulou   +7 more
doaj   +1 more source

Blood coagulation factors and platelet response to drug‐induced hepatitis and hepatosis in rats

open access: yesAnimal Models and Experimental Medicine, 2023
Background Knowing the variability of blood coagulation responses to liver damage of different origins can provide a key to curing liver tissues or to mitigating treatment side effects.
Daria Korolova   +8 more
doaj   +1 more source

Association of prothrombin, FV Leiden and MTHFR gene polymorphisms in the Montenegrin patients with venous thromboembolism [PDF]

open access: yesVojnosanitetski Pregled, 2021
Background/Aim. Polymorphisms of the factor V Leiden (FV G1691A), prothrombin (FII G20210A), and methylene-tetrahydrofolate reductase (MTHFR C677T) genes are the most commonly investigated inherited risk factors for developing venous thromboembolism (VTE)
Teofilov Slađana   +4 more
doaj   +1 more source

Structure of Coagulation Factor II: Molecular Mechanism of Thrombin Generation and Development of Next-Generation Anticoagulants

open access: yesFrontiers in Medicine, 2018
Coagulation factor II, or prothrombin, is a multi-domain glycoprotein that is essential for life and a key target of anticoagulant therapy. In plasma, prothrombin circulates in two forms at equilibrium, “closed” (~80%) and “open” (~20%), brokered by the ...
Mathivanan Chinnaraj   +2 more
doaj   +1 more source

Association of Factor II G20210A, Factor V G1691A and methylenetetrahydrofolate reductase C677T gene polymorphism with different forms of myocardial infarction: ST segment elevation and non-ST segment elevation [PDF]

open access: yesVojnosanitetski Pregled, 2020
Background/Aim. Coagulation Factor II G20210A and Factor V G1691A variants are moderately associated with coronary artery disease. Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene C677T is associated with myocardial infarction (MI) in ...
Ćućuz-Jokić Milica   +4 more
doaj   +1 more source

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