Results 1 to 10 of about 105,223 (244)

Identification of Prothrombin Belgrade Variant in a Mexican–American Family with Recurrent Deep Vein Thrombosis [PDF]

TH Open
A rare prothrombin variant (c.1787G > A, p.Arg596Gln), also known as the prothrombin Belgrade variant, has been associated with an increased predisposition to thrombosis through resistance to antithrombin.
Émile Moura Coelho da Silva, Natalie Montanez, Miguel Escobar   +2 more
doaj   +2 more sources

Prothrombin conversion accelerates with increasing age in women but not in men: findings from the Moli-sani Cohort Study [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: The thrombin dynamics method has been used as an add-on analysis method for the thrombin generation test over the past years to study the balance between pro- and anticoagulant pathways.
Amalia De Curtis, Romy de Laat-Kremers, Simona Costanzo, Augusto Di Castelnuovo, Marisa Ninivaggi, Chiara Cerletti, Giovanni de Gaetano, Maria Benedetta Donati, Licia Iacoviello, Bas de Laat, Licia Iacoviello, Giovanni de Gaetano, Maria Benedetta Donati, Chiara Cerletti, Marialaura Bonaccio, Americo Bonanni, Simona Costanzo, Amalia De Curtis, Augusto Di Castelnuovo, Alessandro Gialluisi, Francesco Gianfagna, Mariarosaria Persichillo, Jos Vermylen, Renzo Pegoraro, Antonio G. Spagnolo, Deodato Assanelli, Livia Rago, Simona Costanzo, Sabatino Orlandi, Teresa Panzera, Augusto Di Castelnuovo, Marialaura Bonaccio, Francesca Bracone, Simona Costanzo, Giuseppe Di Costanzo, Simona Esposito, Alessandro Gialluisi, Anwal Ghulam, Francesco Gianfagna, Martina Morelli, Maria Loreto Muñoz Venegas, Antonietta Pepe, Emilia Ruggiero, Amalia De Curtis, Concetta Civitillo, Alisia Cretella, Sara Magnacca, Mariarosaria Persichillo, Francesca Bracone, Giuseppe Di Costanzo, Martina Morelli, Americo Bonanni   +51 more
doaj   +2 more sources

Coagulation Status and Surgical Approach as Predictors of Postoperative Anemia in Patients Undergoing Thoracic Surgery: A Retrospective Study

Frontiers in Surgery, 2021
Objective: Postoperative anemia is a common complication after a major surgery. Our study aims to identify factors that are associated with higher risk of developing postoperative anemia after thoracic surgery.Methods: We conducted a retrospective study ...
Zhongping Lang, Yue Wu, Minwei Bao
doaj   +1 more source

Antiphospholipid Antibody Assays in 2021: Looking for a Predictive Value in Addition to a Diagnostic One

Frontiers in Immunology, 2021
Antiphospholipid antibodies (aPL) are mandatory for the diagnosis but are also a risk factor for the antiphospholipid syndrome (APS) clinical manifestations.
Pier Luigi Meroni, Maria Orietta Borghi, Maria Orietta Borghi   +2 more
doaj   +1 more source

Association of prothrombin, FV Leiden and MTHFR gene polymorphisms in the Montenegrin patients with venous thromboembolism [PDF]

Vojnosanitetski Pregled, 2021
Background/Aim. Polymorphisms of the factor V Leiden (FV G1691A), prothrombin (FII G20210A), and methylene-tetrahydrofolate reductase (MTHFR C677T) genes are the most commonly investigated inherited risk factors for developing venous thromboembolism (VTE)
Teofilov Slađana, Magić Zvonko, Miljanović Olivera, Ostojić Tatjana, Bulatović Milena   +4 more
doaj   +1 more source

Discovery of Screening Biomarkers for Major Depressive Disorder in Remission by Proteomic Approach

Diagnostics, 2021
Major depressive disorder (MDD) is a common disorder involving depressive mood and decreased motivation. Due to its high heterogeneity, novel biomarkers are required to diagnose MDD.
Hyebin Choi, Sora Mun, Eun-Jeong Joo, Kyu Young Lee, Hee-Gyoo Kang, Jiyeong Lee   +5 more
doaj   +1 more source

Prothrombin expression in cancer-derived cell lines [PDF]

Archives of Biological Sciences, 2019
The link between thrombotic disorders and cancer has been known for over 150 years, although the precise mechanism of this relationship has not yet been resolved.
Dunjić Sofija, Cumbo Marija, Gvozdenov Maja, Tomić Branko, Pruner Iva, Radojković Dragica, Đorđević Valentina   +6 more
doaj   +1 more source

OPTIMIZATION OF THE EVALUATION METHOD OF THE PERFORMANCE OF THERAPY USING INDIRECT ACTION ANTICOAGULANTS [PDF]

Biotechnologia Acta, 2022
Aim. Treatment by indirect anticoagulants (vitamin K antagonists) requires a personalized approach for controlling the overall level of prothrombin and the accumulation of its decarboxylated forms.
D. S. Korolova, O. V. Hornytska, V. A. Deyev, V. I. Gryshchuk, T. M. Chernyshenko, T. M. Platonova, V. O. Chernyshenko   +6 more
doaj   +1 more source

Large‐scale screening for factor V Leiden (G1691A), prothrombin (G20210A), and MTHFR (C677T) mutations in Greek population

Health Science Reports, 2022
Background and aims To provide a fair estimate of the prevalence of factor V Leiden (FVL) (G1691A), prothrombin (G20210A), and MTHFR (C677T) mutations in the Greek population.
Alkistis Raptopoulou, Vassiliki Michou, Niki Mourtzi, Efstathia G. Papageorgiou, Chrysa Voyiatzaki, Vassilis Tsilivakos, Apostolos Beloukas, Thaleia A. Bei   +7 more
doaj   +1 more source

Blood coagulation factors and platelet response to drug‐induced hepatitis and hepatosis in rats

Animal Models and Experimental Medicine, 2023
Background Knowing the variability of blood coagulation responses to liver damage of different origins can provide a key to curing liver tissues or to mitigating treatment side effects.
Daria Korolova, Viktoriya Gryshchenko, Tamara Chernyshenko, Oleh Platonov, Olha Hornytska, Volodymyr Chernyshenko, Pavlo Klymenko, Yevdokiia Reshetnik, Tetyana Platonova   +8 more
doaj   +1 more source