Results 111 to 120 of about 153,345 (297)

In vivo increase in thrombin generation by four‐factor prothrombin complex concentrate in apixaban‐treated healthy volunteers

Journal of Thrombosis and Haemostasis, 2015
Y. W. Cheung, Stefano Barco, B. Hutten, J. Meijers, S. Middeldorp, M. Coppens   +5 more
semanticscholar   +1 more source

Anti‐PF4 disorders: Pathogenesis, diagnosis and treatment

British Journal of Haematology, EarlyView.
Anti‐platelet factor 4 (PF4) disorders include heparin‐induced thrombocytopenia (HIT) and vaccine‐induced immune thrombocytopenia and thrombosis (VITT)/VITT‐like disorders. The formation of immunoglobulin G (IgG)/PF4 immune complexes facilitates uncontrolled activation of platelets, neutrophils and monocytes via IgG‐mediated Fcγ receptor binding.
Megan V. Preece, Devi V. Pathak, Mike Laffan, Deepa J. Arachchillage   +3 more
wiley   +1 more source

Effective Reversal of Edoxaban-associated Bleeding with Four-factor Prothrombin Complex Concentrate in a Rabbit Model of Acute Hemorrhage

Anesthesiology, 2015
E. Herzog, F. Kaspereit, Wilfried Krege, Baerbel Doerr, J. Mueller-Cohrs, I. Pragst, Y. Morishima, G. Dickneite   +7 more
semanticscholar   +1 more source

Liver Cirrhosis Secondary to Overlap Autoimmune Liver Disease as the Initial Presentation of Sjögren's Syndrome

Portal Hypertension &Cirrhosis, EarlyView.
Saikrishna R. Bana, Prabhanjan V. Kulkarni, Jagannath S. Dhadwad, Roushan Kumar   +3 more
wiley   +1 more source

Improved Instrumentation for the Determination of Prothrombin Activity [PDF]

, 1965
Rex E. Sterling, Alan A Wilcox, Arnold G. Ware, Mary K. Umehara   +3 more
openalex   +1 more source

Comparison of three‐factor and four‐factor prothrombin complex concentrates regarding reversal of the anticoagulant effects of rivaroxaban in healthy volunteers

Journal of Thrombosis and Haemostasis, 2014
M. Levi, K. Moore, C. F. Castillejos, D. Kubitza, S. Berkowitz, S. Goldhaber, M. Raghoebar, M. Patel, J. Weitz, J. Levy   +9 more
semanticscholar   +1 more source

Tumor Endothelial Cells Induce M2 Macrophage Polarization via IL‐4, Enhancing Tumor Growth in Hepatocellular Carcinoma

Cancer Science, EarlyView.
Tumor endothelial cells (TECs) promote the polarization of macrophages to M2 subtype by secreting IL‐4. Downregulation of IL‐4 in TECs suppressed M2 polarization and tumor progression. A high abundance of both TECs and M2 macrophages in HCC specimens is associated with poor prognosis.
Daijiro Matoba, Takehiro Noda, Shogo Kobayashi, Yoshihiro Sakano, Kenichi Matsumoto, Chihiro Yamanaka, Kazuki Sasaki, Shinichiro Hasegawa, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Hidenori Takahashi, Tadafumi Asaoka, Junzo Shimizu, Hisashi Wada, Yuichiro Doki, Hidetoshi Eguchi   +17 more
wiley   +1 more source

Enoxaparin Failure in Patient With Cerebral Venous Sinus Thrombosis and Prothrombin G20210A Mutation: Case Report. [PDF]

Neurologist
Polavarapu A, Bhushan A, Duarte-Celada W, Windisch T, Bhushan B.   +4 more
europepmc   +1 more source

THE CONVERSION OF PROTHROMBIN TO THROMBIN, FOLLOWED BY MEANS OF THE RADIOACTIVE PHOSPHORUS ISOTOPE

, 1940
Erwin Chargaff, Morris Ziff, Seymour S. Cohen   +2 more
openalex   +1 more source

RNA Analysis Uncovers Pathogenic PARN Variant in Dyskeratosis Congenita

Clinical Genetics, EarlyView.
Using WGS and RNA analysis, we identified a branch point‐disrupting variant in the PARN gene and elucidated its pathogenic molecular mechanism in a child with atypical dyskeratosis congenita presentation. ABSTRACT Dyskeratosis congenita (DC) is a rare genetic disorder caused by impaired telomere maintenance, leading to diverse clinical manifestations ...
Daria Akimova, Natalia Semenova, Tatiana Cherevatova, Mikhail Skoblov   +3 more
wiley   +1 more source