Results 121 to 130 of about 105,223 (244)

Valproic acid for treatment of traumatic brain injury: Study protocol for the VIBRANT prospective randomized trial

open access: yesTransfusion, EarlyView.
Abstract Background Traumatic brain injury (TBI) carries significant mortality and morbidity in civilian and military populations. Current treatment guidelines for TBI are primarily supportive, and no pharmacological agent exists to attenuate the progression of brain injury.
Maxime A. Visa   +9 more
wiley   +1 more source

Endothelial thrombomodulin—Its role in trauma‐induced coagulopathy

open access: yesTransfusion, EarlyView.
Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Jeries Abu‐Hanna   +7 more
wiley   +1 more source

Prothrombin and Haemorrhage [PDF]

open access: yesBMJ, 1954
A C, DONALD   +4 more
openaire   +2 more sources

Early exposure, enduring consequences: How do I manage Rh immunoglobulin prophylaxis after Rh‐mismatched transfusions in children?

open access: yesTransfusion, EarlyView.
Abstract Background RhD mismatched transfusions in RhD negative women have the potential to impact future pregnancies through alloimmunization and development of hemolytic disease of the fetus and newborn (HDFN). As use of RhD positive emergency‐release blood products in pediatric trauma has increased, it has become clear that a significant ...
Kirea Lange   +7 more
wiley   +1 more source

Effect of Nutritional Status on Coagulation and Inflammation in Patients With Cirrhosis and Variceal Bleeding. [PDF]

open access: yesMed Sci Monit
Yindi T   +11 more
europepmc   +1 more source

Estrogen as a therapeutic agent: Targeting endotheliopathy and coagulopathy in trauma

open access: yesTransfusion, EarlyView.
Abstract Background Traumatic injury remains a leading cause of death, often due to uncontrolled hemorrhage and trauma‐induced coagulopathy (TIC). TIC is critically triggered by the endotheliopathy of trauma, involving endothelial cell injury and glycocalyx degradation. Despite conventional advances, the stable casualty rate underscores the urgent need
Niruktha Raghavan   +4 more
wiley   +1 more source

An assessment of green plasma: The in vitro hemostatic superiority of a currently discarded blood product

open access: yesTransfusion, EarlyView.
Abstract Introduction Recent studies have linked trauma patient outcomes to the plasma donor's sex, with premenopausal females associated with improved survival and lower organ failure. Currently, green‐colored plasma (due to oral contraceptive use) is removed from the donor pool. We set out to evaluate the hemostatic potential of green plasma.
Samantha C. Redden   +6 more
wiley   +1 more source

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