Results 21 to 30 of about 105,223 (244)

Factor V G1691A (Leiden) is a major etiological factor in Egyptian Budd-Chiari syndrome patients

Turkish Journal of Hematology, 2011
OBJECTIVE: Budd-Chiari syndrome is a multifactorial disease in which several prothrombotic disorders may predispose patients to the development of thrombosis at this uncommon location (hepatic veins). The aim of this study was to determine the prevalence
Tawhida Y. Abdel Ghaffar, Solaf M. Elsayed, Mohamed A. Sakr, Ezzat S. Elsobky, Sara M. Abdelhakam, Said Yousuf, Yonca Eğin, Nejat Akar   +7 more
doaj   +3 more sources

Controle do tempo de protrombina em sangue capilar e venoso em pacientes com anticoagulação oral: correlação e concordância Comparative study of a portable system for prothrombin monitoring using capillary blood against venous blood measurements in patients using oral anticoagulants: correlation and concordance

Arquivos Brasileiros de Cardiologia, 2007
FUNDAMENTO: O uso de anticoagulantes orais (ACO) é comum na prática cardiológica, tendo como principais indicações a fibrilação atrial e próteses valvares. Os pacientes em uso de ACO necessitam de controle freqüente do tempo de protrombina (TP).
Tiago Luiz Luz Leiria, Lúcia Campos Pellanda, Eros Magalhães, Gustavo Glotz de Lima   +3 more
doaj   +1 more source

Anti-Phosphatidylserine, Anti-Prothrombin, and Anti-Annexin V Autoantibodies in Antiphospholipid Syndrome: A Real-Life Study

Diagnostics, 2023
The antiphospholipid antibodies (aPL) increase the risk of developing thrombotic events and may coexist with a variety of autoimmune diseases. They can be detected chronically or temporarily in patients with infectious diseases, during drug therapy, or ...
Daniele Roselli, Maria Addolorata Bonifacio, Giovanna Barbuti, Maria Rosaria Rossiello, Prudenza Ranieri, Maria Addolorata Mariggiò   +5 more
doaj   +1 more source

Association of Factor II G20210A, Factor V G1691A and methylenetetrahydrofolate reductase C677T gene polymorphism with different forms of myocardial infarction: ST segment elevation and non-ST segment elevation [PDF]

Vojnosanitetski Pregled, 2020
Background/Aim. Coagulation Factor II G20210A and Factor V G1691A variants are moderately associated with coronary artery disease. Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene C677T is associated with myocardial infarction (MI) in ...
Ćućuz-Jokić Milica, Ilić Vesna, Cikota-Aleksić Bojana, Obradović Slobodan, Magić Zvonko   +4 more
doaj   +1 more source

Inherited thrombophilia and portal vein thrombosis in cirrhosis: A systematic review and meta‐analysis

Research and Practice in Thrombosis and Haemostasis, 2019
Background Portal vein thrombosis (PVT) is common in cirrhosis. PVT is associated with high morbidity and mortality. Individual reports suggest that PVT occurs more frequently in patients with cirrhosis and inherited thrombophilia.
Steven D. Ma, Jennifer Wang, Dmitri Bezinover, Zakiyah Kadry, Patrick G. Northup, Jonathan G. Stine   +5 more
doaj   +1 more source

The Activation of Prothrombin Seems to Play an Earlier Role than the Complement System in the Progression of Colorectal Cancer: A Mass Spectrometry Evaluation

Diagnostics, 2020
Colorectal cancer (CRC) is the second cause of death in men and the third in women. This work deals with the study of the low molecular weight protein fraction of sera from patients who underwent surgery for CRC and who were followed for several years ...
Maider Beitia, Paolo Romano, Gorka Larrinaga, Jon Danel Solano-Iturri, Annalisa Salis, Gianluca Damonte, Marco Bruzzone, Marcello Ceppi, Aldo Profumo   +8 more
doaj   +1 more source

Association of Factor V Leiden and Prothrombin G20210A Polymorphisms in Women with Recurrent Pregnancy Loss in Isfahan Province, Iran

International Journal of Preventive Medicine, 2018
Background: Maternal thrombophilia has been identified as a risk factor for recurrent pregnancy loss (RPL). The aim of this study was to investigate the association between prothrombin G20210A and factor V Leiden (FVL) polymorphisms in women with RPL and
Mohammad Taghi Kardi, Elham Yousefian, Azra Allahveisi, Sanaz Alaee   +3 more
doaj   +1 more source

Factor V Leiden (R506Q), Prothrombin G20210A, and MTHFR C677T Variants and Thrombophilia in Qatar Biobank Participants: A Case Control Study

Pathophysiology
Background: Thrombophilia, a predisposition to develop blood clots, is very common and can have serious sequelae. Aim: This study aimed to determine the prevalence of three thrombophilia-related genetic variants—factor V Leiden (FVL), prothrombin (F2 ...
Sapha Shibeeb, Nada Al-Rayashi, Nehal Shams, Tameem Hadvan, Ejaife O. Agbani, Atiyeh M. Abdallah   +5 more
doaj   +1 more source

Cryo‐EM structures of coagulation factors

Research and Practice in Thrombosis and Haemostasis, 2022
A State of the Art lecture titled “Cryo‐EM structures of coagulation factors” was presented at the ISTH Congress in 2022. Cryogenic electron microscopy (cryo‐EM) is a revolutionary technique capable of solving the structure of high molecular weight ...
Enrico Di Cera, Bassem M. Mohammed, Leslie A. Pelc, Bosko M. Stojanovski   +3 more
doaj   +1 more source

Multivariate Analysis of Protein–Nanoparticle Binding Data Reveals a Selective Effect of Nanoparticle Material on the Formation of Soft Corona

Nanomaterials, 2023
When nanoparticles are introduced into the bloodstream, plasma proteins accumulate at their surface, forming a protein corona. This corona affects the properties of intravenously administered nanomedicines.
Susannah Emily Cornwell, Sarah Ogechukwu Okocha, Enrico Ferrari   +2 more
doaj   +1 more source