Results 11 to 20 of about 5,052 (178)
Bottom-up Strategies for Generating Polymer Protocells That Mimic Cellular Communication. [PDF]
ChemistryThis review focuses on polymeric protocells produced using a bottom‐up approach. Polymer‐based assemblies guarantee stability and designability by adjusting the properties of the amphiphilic copolymers used. The review covers protocell architectures, production, and their intra‐ and intercellular communication mechanisms.
Saorin G, Huang X, Mihali V, Palivan CG.
europepmc +2 more sources
Current Biology, 2020 Lai and Chen introduce the role of compartmentalization in the evolution of life.
Yei-Chen, Lai, Irene A, Chen
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Colony-like Protocell Superstructures [PDF]
Biophysical Journal, 2021 AbstractWe report the formation, growth, and dynamics of model protocell superstructures on solid surfaces, resembling single cell colonies. These structures, consisting of several layers of lipidic compartments enveloped in a dome-shaped outer lipid bilayer, emerged as a result of spontaneous shape transformation of lipid agglomerates deposited on ...
Katke, Chinmay +5 more
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The Effect of Environment on the Evolution and Proliferation of Protocells of Increasing Complexity
Life, 2022 The formation, growth, division and proliferation of protocells containing RNA strands is an important step in ensuring the viability of a mixed RNA–lipid world.
Suvam Roy, Supratim Sengupta
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Microscopy techniques for protocell characterization
Polymer Testing, 2021 Recent advances have witnessed the research progress of synthetic preliminary forms of cell-like entities (protocells) towards understanding the origin of life.
Hua Wu, Yan Qiao
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Introduction. Artificial protocells [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2007 What makes a cell? How are cells able to replicate themselves in a stable manner? How did cellular life emerge on our planet? The answer to these fundamental questions lies at the base of biology.
Solé, Richard V. +2 more
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Creating complex protocells and prototissues using simple DNA building blocks
Nature Communications, 2023 Building synthetic protocells and prototissues hinges on the formation of biomimetic skeletal frameworks. Here, the authors harness simplicity to create complexity by assembling DNA subunits into structural frameworks which support membrane-based ...
Nishkantha Arulkumaran +3 more
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Life, 2023 How functional peptides may have arisen is a significant problem for the scenario of the RNA world. An attractive idea, the direct RNA template (DRT) hypothesis, proposes that RNA molecules can bind amino acids specifically and promote the synthesis of ...
Yu Shi, Chunwu Yu, Wentao Ma
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Bioinspired Networks of Communicating Synthetic Protocells
Frontiers in Molecular Biosciences, 2021 The bottom-up synthesis of cell-like entities or protocells from inanimate molecules and materials is one of the grand challenges of our time. In the past decade, researchers in the emerging field of bottom-up synthetic biology have developed different ...
Patrick J. Grimes +4 more
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Engineering Polymersome Protocells [PDF]
The Journal of Physical Chemistry Letters, 2011 The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be made from synthetic, biological or hybrid polymers and can be used ...
Neha P, Kamat +2 more
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