Results 41 to 50 of about 3,247 (202)

Macrophage Reprogramming with Anti‐miR223‐Loaded Artificial Protocells Enhances In Vivo Cancer Therapeutic Potential

open access: yesAdvanced Science, 2022
Several immune cell‐expressed miRNAs (miRs) are associated with altered prognostic outcome in cancer patients, suggesting that they may be potential targets for development of cancer therapies.
Paco López‐Cuevas   +7 more
doaj   +1 more source

Synthetic protocells interact with viral nanomachinery and inactivate pathogenic human virus.

open access: yesPLoS ONE, 2011
We present a new antiviral strategy and research tool that could be applied to a wide range of enveloped viruses that infect human beings via membrane fusion.
Matteo Porotto   +3 more
doaj   +1 more source

Additional file 2 of Non-interfacial self-assembly of synthetic protocells

open access: yes, 2023
Additional file 2: video S1 Confocal micrograph of synthetic ...
Xiaolin Xu (493031)   +4 more
core   +1 more source

Survival of RNA Replicators Is Much Easier in Protocells Than in Surface-Based, Spatial Systems

open access: yesLife, 2019
In RNA-World scenarios for the origin of life, replication is catalyzed by polymerase ribozymes. Replicating RNA systems are subject to invasion by non-functional parasitic strands. It is well-known that there are two ways to avoid the destruction of the
Vismay Shah   +4 more
doaj   +1 more source

Dynamical models of protocells and synchronization

open access: yes, 2017
Let us now consider the contributions that a complex systems approach can provide to the research on ...
Villani M.   +3 more
core   +1 more source

Model Protocells from Single-Chain Lipids

open access: yes, 2009
Significant progress has been made in the construction of laboratory models of protocells. Most frequently the developed vesicle systems utilize single-chain lipids rather than the double-chain lipids typically found in biological membranes.
Sheref S. Mansy
core   +1 more source

Coevolution of compositional protocells and their environment [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2007
The coevolution of environment and living organisms is well known in nature. Here, it is suggested that similar processes can take place before the onset of life, where protocellular entities, rather than full-fledged living systems, coevolve along with their surroundings.
Barak, Shenhav, Aia, Oz, Doron, Lancet
openaire   +2 more sources

Life‐Like Ferrous Oxide Microspheres from Kombucha

open access: yesAdvanced Materials Interfaces, EarlyView.
Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis   +2 more
wiley   +1 more source

From molecular to cellular form: modeling the first major transition during the arising of life

open access: yesBMC Evolutionary Biology, 2019
Background It has long been suggested that Darwinian evolution may have started at the molecular level and subsequently proceeded to a level with membrane boundary, i.e., of protocells.
Shaolin Yin   +3 more
doaj   +1 more source

pH‐Gated Activation of Gene Transcription and Translation in Biocatalytic Metal–Organic Framework Artificial Cells

open access: yesAdvanced NanoBiomed Research, 2021
Regulating gene expression is an important goal for the development of artificial cells that have the ability to replicate the functions of living cells.
Jian Liu   +9 more
doaj   +1 more source

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