Results 31 to 40 of about 3,247 (202)

Engineering Polymersome Protocells [PDF]

open access: yesThe Journal of Physical Chemistry Letters, 2011
The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be made from synthetic, biological or hybrid polymers and can be used ...
Neha P, Kamat   +2 more
openaire   +2 more sources

Nonreplicating Protocells

open access: yesAccounts of Chemical Research, 2012
Prebiotic soup experiments have shown that the molecular building blocks of life can be built under prebiotically plausible conditions. From this starting point, researchers have launched continued studies of polymerization and explorations of the breadth of RNA function.
Del Bianco, Cristina   +1 more
openaire   +2 more sources

Shape Deformation, Budding and Division of Giant Vesicles and Artificial Cells: A Review

open access: yesLife, 2022
The understanding of the shape-change dynamics leading to the budding and division of artificial cells has gained much attention in the past few decades due to an increased interest in designing stimuli-responsive synthetic systems and minimal models of ...
Ylenia Miele   +3 more
doaj   +1 more source

Origin of Life: Protocells Red in Tooth and Claw. [PDF]

open access: yes, 2015
To study the origin of life, synthetic biologists construct simple 'protocells', but previous models were not able to reproduce both genome and membrane sustainably.
Saha, Ranajay, Chen, Irene A
core   +1 more source

Simulating populations of protocells with uneven division [PDF]

open access: yes, 2018
Protocells should be similar to present-day biological cells, but much simpler. They are believed to have played a key role in the origin of life, and they may also be the basis of a new technology with tremendous opportunities. In this work we study the
Marco Villani   +5 more
core   +1 more source

Nanoporous Silica-Based Protocells at Multiple Scales for Designs of Life and Nanomedicine

open access: yesLife, 2015
Various protocell models have been constructed de novo with the bottom-up approach. Here we describe a silica-based protocell composed of a nanoporous amorphous silica core encapsulated within a lipid bilayer built by self-assembly that provides for ...
Jie Sun   +3 more
doaj   +1 more source

Recent progress in primitive polyester synthesis and membraneless microdroplet assembly

open access: yesBiophysics and Physicobiology, 2023
While it is often believed that the origins of life required participation of early biomolecules, it has been recently proposed that “non-biomolecules”, which would have been just as, if not more, abundant on early Earth, could have played a part.
Tony Z. Jia, Kuhan Chandru
doaj   +1 more source

Multifunctional Nanoassemblies for Cytotoxic Drug and Therapeutic Enzymes Delivery in Neuroblastoma Therapy

open access: yesAdvanced Materials Interfaces, 2023
Neuroblastoma cells can acquire resistance mechanisms that make them invulnerable to chemotherapeutic agents. The use of nanoparticles as drug carriers provides the possibility to deliver several drugs simultaneously to specific tumoral cell populations,
Jorge Parra‐Nieto   +8 more
doaj   +1 more source

Supramolecular nanoscaffolds within cytomimetic protocells as signal localization hubs

open access: yes, 2020
The programmed construction of functional synthetic cells requires spatial control over arrays of biomolecules within the cytomimetic environment. The mimicry of the natural hierarchical assembly of biomolecules remains challenging due to the lack of an ...
Mason, Alexander F   +4 more
core   +1 more source

Investigating Prebiotic Protocells for a Comprehensive Understanding of the Origins of Life: A Prebiotic Systems Chemistry Perspective

open access: yesLife, 2019
Protocells are supramolecular systems commonly used for numerous applications, such as the formation of self-evolvable systems, in systems chemistry and synthetic biology.
Augustin Lopez, Michele Fiore
doaj   +1 more source

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