Results 51 to 60 of about 5,117 (196)
Twenty years of "Lipid World": a fertile partnership with David Deamer [PDF]
"The Lipid World" was published in 2001, stemming from a highly effective collaboration with David Deamer during a sabbatical year 20 years ago at the Weizmann Institute of Science in Israel.
Kahana, Amit +2 more
core +1 more source
Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo +3 more
wiley +1 more source
Regulating gene expression is an important goal for the development of artificial cells that have the ability to replicate the functions of living cells.
Jian Liu +9 more
doaj +1 more source
Is defining life pointless? Operational definitions at the frontiers of Biology [PDF]
Despite numerous and increasing attempts to define what life is, there is no consensus on necessary and sufficient conditions for life. Accordingly, some scholars have questioned the value of definitions of life and encouraged scientists and philosophers
Bich, Leonardo, Green, Sara
core +8 more sources
Design of Fuel‐Dependent, Complex‐Coacervate‐Based Synthetic Cells
Fuel‐dependent synthetic cells form and persist only in the presence of chemical fuel, decaying under starvation. We establish design rules for hexapeptide‐based coacervates, showing that tryptophan enhances polyanion binding, extends lifetime, and reduces waste sensitivity.
Anna‐Lena Holtmannspötter +9 more
wiley +1 more source
A spatial model of autocatalytic reactions
Biological cells with all of their surface structure and complex interior stripped away are essentially vesicles - membranes composed of lipid bilayers which form closed sacs.
Alan J. McKane +12 more
core +2 more sources
UV-light-driven prebiotic synthesis of iron–sulfur clusters [PDF]
Iron–sulfur clusters are ancient cofactors that play a fundamental role in metabolism and may have impacted the prebiotic chemistry that led to life.
Bonfio, Claudia +13 more
core +1 more source
Switchable or transient formation and dissociation of the phase‐separated DNA microdroplets generated by metal ions or aptamer‐ligand complexes crosslinking Y‐shaped DNA frameworks and dynamically separated by counter ligands eliminating the bridging metal ions or biocatalysts degrading the aptamer‐ligand complexes, are introduced.
Yichen Han +6 more
wiley +1 more source
Sequence‐Modulated Active Tripeptide Condensates for Tandem Catalysis
Sequence‐modulated tripeptide coacervates mimic biomolecular condensates with controllable, enzyme‐regulated phase separation. They co‐sequester hydrophobic active species and hydrophilic enzymes, enabling tandem catalysis in aqueous media. Incorporated into artificial cells, they function as adaptive sub‐organelles, orchestrating compartmentalized ...
Hao Han +7 more
wiley +2 more sources
Putative roles of terpenoids in primitive membranes
For the continuation and evolution of life, primitive membranes formed from prebiotically available components must have fulfilled certain essential requirements. Candidate amphiphiles, such as straight-chain fatty acids, that can self-assemble into cell-
Joshua P. King +3 more
doaj +1 more source

