Results 51 to 60 of about 5,117 (196)

Twenty years of "Lipid World": a fertile partnership with David Deamer [PDF]

open access: yes, 2019
"The Lipid World" was published in 2001, stemming from a highly effective collaboration with David Deamer during a sabbatical year 20 years ago at the Weizmann Institute of Science in Israel.
Kahana, Amit   +2 more
core   +1 more source

Bottom‐Up Coacervate‐Based Artificial Cells: Integrating Cellular Hallmarks into Complex Life‐Like Systems

open access: yesAngewandte Chemie International Edition, EarlyView.
Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo   +3 more
wiley   +1 more source

pH‐Gated Activation of Gene Transcription and Translation in Biocatalytic Metal–Organic Framework Artificial Cells

open access: yesAdvanced NanoBiomed Research, 2021
Regulating gene expression is an important goal for the development of artificial cells that have the ability to replicate the functions of living cells.
Jian Liu   +9 more
doaj   +1 more source

Is defining life pointless? Operational definitions at the frontiers of Biology [PDF]

open access: yes, 2016
Despite numerous and increasing attempts to define what life is, there is no consensus on necessary and sufficient conditions for life. Accordingly, some scholars have questioned the value of definitions of life and encouraged scientists and philosophers
Bich, Leonardo, Green, Sara
core   +8 more sources

Design of Fuel‐Dependent, Complex‐Coacervate‐Based Synthetic Cells

open access: yesChemistry – A European Journal, EarlyView.
Fuel‐dependent synthetic cells form and persist only in the presence of chemical fuel, decaying under starvation. We establish design rules for hexapeptide‐based coacervates, showing that tryptophan enhances polyanion binding, extends lifetime, and reduces waste sensitivity.
Anna‐Lena Holtmannspötter   +9 more
wiley   +1 more source

A spatial model of autocatalytic reactions

open access: yes, 2010
Biological cells with all of their surface structure and complex interior stripped away are essentially vesicles - membranes composed of lipid bilayers which form closed sacs.
Alan J. McKane   +12 more
core   +2 more sources

UV-light-driven prebiotic synthesis of iron–sulfur clusters [PDF]

open access: yes, 2017
Iron–sulfur clusters are ancient cofactors that play a fundamental role in metabolism and may have impacted the prebiotic chemistry that led to life.
Bonfio, Claudia   +13 more
core   +1 more source

Dynamic Switchable and Transient DNA Condensates Driven by Aptamer‐Ligand or Ion‐Nucleobase Bridged Complexes

open access: yesSmall, EarlyView.
Switchable or transient formation and dissociation of the phase‐separated DNA microdroplets generated by metal ions or aptamer‐ligand complexes crosslinking Y‐shaped DNA frameworks and dynamically separated by counter ligands eliminating the bridging metal ions or biocatalysts degrading the aptamer‐ligand complexes, are introduced.
Yichen Han   +6 more
wiley   +1 more source

Sequence‐Modulated Active Tripeptide Condensates for Tandem Catalysis

open access: yesAngewandte Chemie, Volume 138, Issue 13, 23 March 2026.
Sequence‐modulated tripeptide coacervates mimic biomolecular condensates with controllable, enzyme‐regulated phase separation. They co‐sequester hydrophobic active species and hydrophilic enzymes, enabling tandem catalysis in aqueous media. Incorporated into artificial cells, they function as adaptive sub‐organelles, orchestrating compartmentalized ...
Hao Han   +7 more
wiley   +2 more sources

Putative roles of terpenoids in primitive membranes

open access: yesFrontiers in Ecology and Evolution, 2023
For the continuation and evolution of life, primitive membranes formed from prebiotically available components must have fulfilled certain essential requirements. Candidate amphiphiles, such as straight-chain fatty acids, that can self-assemble into cell-
Joshua P. King   +3 more
doaj   +1 more source

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