Results 11 to 20 of about 5,117 (196)
Polymeric Giant Unilamellar Vesicles Support Longevity of Native Nuclei in Protocells [PDF]
Small ScienceProtocells offer a versatile material for dissecting cellular processes and developing simplified biomimetic systems by combining biological components with synthetic ones.
Lukas Heuberger +7 more
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Self-growing protocell models in aqueous two-phase system induced by internal DNA replication reaction [PDF]
Nature CommunicationsThe bottom-up reconstitution of self-growing artificial cells is a critical milestone toward realizing autonomy and evolvability. However, building artificial cells that exhibit self-growth coupled with internal replication of gene-encoding DNA has not ...
Yoshihiro Minagawa +3 more
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On the nature of the earliest known lifeforms [PDF]
eLifeMicrofossils from the Paleoarchean Eon are the oldest known evidence of life. Despite their significance in understanding the history of life on Earth, any interpretation of the nature of these microfossils has been a point of contention among ...
Dheeraj Kanaparthi +8 more
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Current Biology, 2020 Lai and Chen introduce the role of compartmentalization in the evolution of life.
Yei-Chen, Lai, Irene A, Chen
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The Effect of Environment on the Evolution and Proliferation of Protocells of Increasing Complexity
Life, 2022 The formation, growth, division and proliferation of protocells containing RNA strands is an important step in ensuring the viability of a mixed RNA–lipid world.
Suvam Roy, Supratim Sengupta
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Microscopy techniques for protocell characterization
Polymer Testing, 2021 Recent advances have witnessed the research progress of synthetic preliminary forms of cell-like entities (protocells) towards understanding the origin of life.
Hua Wu, Yan Qiao
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Colony-like Protocell Superstructures [PDF]
Biophysical Journal, 2021 Abstract We report the formation, growth, and dynamics of model protocell superstructures on solid surfaces, resembling single cell colonies. These structures, consisting of several layers of lipidic compartments enveloped in a dome-shaped outer lipid bilayer, emerged as a result of spontaneous shape transformation of lipid agglomerates
Katke, Chinmay +5 more
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Creating complex protocells and prototissues using simple DNA building blocks
Nature Communications, 2023 Building synthetic protocells and prototissues hinges on the formation of biomimetic skeletal frameworks. Here, the authors harness simplicity to create complexity by assembling DNA subunits into structural frameworks which support membrane-based ...
Nishkantha Arulkumaran +3 more
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Life, 2023 How functional peptides may have arisen is a significant problem for the scenario of the RNA world. An attractive idea, the direct RNA template (DRT) hypothesis, proposes that RNA molecules can bind amino acids specifically and promote the synthesis of ...
Yu Shi, Chunwu Yu, Wentao Ma
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Bioinspired Networks of Communicating Synthetic Protocells
Frontiers in Molecular Biosciences, 2021 The bottom-up synthesis of cell-like entities or protocells from inanimate molecules and materials is one of the grand challenges of our time. In the past decade, researchers in the emerging field of bottom-up synthetic biology have developed different ...
Patrick J. Grimes +4 more
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