Results 41 to 50 of about 5,052 (178)
Protocells are supramolecular systems commonly used for numerous applications, such as the formation of self-evolvable systems, in systems chemistry and synthetic biology.
Augustin Lopez, Michele Fiore
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Natural selection. III. Selection versus transmission and the levels of selection [PDF]
George Williams defined an evolutionary unit as hereditary information for which the selection bias between competing units dominates the informational decay caused by imperfect transmission.
Frank, Steven A.
core +2 more sources
Passive endocytosis in model protocells
AbstractSemipermeable membranes are a key feature of all living organisms. While specialized membrane transporters in cells can import otherwise impermeable nutrients, the earliest cells would have lacked a mechanism to import nutrients rapidly under nutrient-rich circumstances.
Stephanie J. Zhang +6 more
openaire +4 more sources
Several immune cell‐expressed miRNAs (miRs) are associated with altered prognostic outcome in cancer patients, suggesting that they may be potential targets for development of cancer therapies.
Paco López‐Cuevas +7 more
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Synthetic protocells interact with viral nanomachinery and inactivate pathogenic human virus.
We present a new antiviral strategy and research tool that could be applied to a wide range of enveloped viruses that infect human beings via membrane fusion.
Matteo Porotto +3 more
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Sequence‐Modulated Active Tripeptide Condensates for Tandem Catalysis
Sequence‐modulated tripeptide coacervates mimic biomolecular condensates with controllable, enzyme‐regulated phase separation. They co‐sequester hydrophobic active species and hydrophilic enzymes, enabling tandem catalysis in aqueous media. Incorporated into artificial cells, they function as adaptive sub‐organelles, orchestrating compartmentalized ...
Hao Han +7 more
wiley +2 more sources
Dynamic Transcription Machineries in Protocells. [PDF]
Transcription machineries play key roles in nature by regulating diverse cellular processes, including cell cycle progression, the control of intracellular metabolic balance, and cell differentiation and growth. These processes are regulated by the programmed transcription factor-mediated operation of transcription machineries and cellular ...
Dong J, Xia F, Huang F, Willner I.
europepmc +3 more sources
UV-light-driven prebiotic synthesis of iron–sulfur clusters [PDF]
Iron–sulfur clusters are ancient cofactors that play a fundamental role in metabolism and may have impacted the prebiotic chemistry that led to life.
Bonfio, Claudia +13 more
core +1 more source
Numerous living systems are hierarchically organised, whereby replicating components are grouped into reproducing collectives -- e.g., organelles are grouped into cells, and cells are grouped into multicellular organisms.
Kaneko, Kunihiko +2 more
core +1 more source
Survival of RNA Replicators Is Much Easier in Protocells Than in Surface-Based, Spatial Systems
In RNA-World scenarios for the origin of life, replication is catalyzed by polymerase ribozymes. Replicating RNA systems are subject to invasion by non-functional parasitic strands. It is well-known that there are two ways to avoid the destruction of the
Vismay Shah +4 more
doaj +1 more source

