Results 11 to 20 of about 11,109 (130)
Scientific Reports, 2023 Vaccine discovery against eukaryotic parasites is not trivial as highlighted by the limited number of known vaccines compared to the number of protozoal diseases that need one. Only three of 17 priority diseases have commercial vaccines.
Stephen J. Goodswen +2 more
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VLP-Based Vaccines as a Suitable Technology to Target Trypanosomatid Diseases
Vaccines, 2021 Research on vaccines against trypanosomatids, a family of protozoa that cause neglected tropical diseases, such as Chagas disease, leishmaniasis, and sleeping sickness, is a current need.
Aline Maria Vasconcelos Queiroz +4 more
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Recent Advances in the Development of Adenovirus-Vectored Vaccines for Parasitic Infections
Pharmaceuticals, 2023 Vaccines against parasites have lagged centuries behind those against viral and bacterial infections, despite the devastating morbidity and widespread effects of parasitic diseases across the globe.
Cal Koger-Pease +2 more
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Melittin as a promising anti-protozoan peptide: current knowledge and future prospects
AMB Express, 2021 Protozoan diseases such as malaria, leishmaniasis, Chagas disease, and sleeping sickness still levy a heavy toll on human lives. Deplorably, only few classes of anti-protozoan drugs have thus far been developed. The problem is further compounded by their
Hamed Memariani, Mojtaba Memariani
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Advances in understanding immunity to Toxoplasma gondii
Memorias do Instituto Oswaldo Cruz, 2009 Toxoplasma gondii is an important cause of clinical disease in fetuses, infants and immunocompromised patients. Since the discovery of T. gondii 100 years ago, this pathogen and the host's immune response to toxoplasmosis have been studied intensely ...
Elia D Tait, Christopher A Hunter
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Parasite Carbohydrate Vaccines
Frontiers in Cellular and Infection Microbiology, 2017 Vaccination is an efficient means of combating infectious disease burden globally. However, routine vaccines for the world's major human parasitic diseases do not yet exist. Vaccines based on carbohydrate antigens are a viable option for parasite vaccine
Jonnel A. Jaurigue +3 more
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Pre-Erythrocytic Vaccines against Malaria
Vaccines, 2020 Malaria, caused by the protozoan Plasmodium, is a devastating disease with over 200 million new cases reported globally every year. Although immunization is arguably the best strategy to eliminate malaria, despite decades of research in this area we do ...
Camila Marques-da-Silva +2 more
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Recent Progress in Vaccine Development against Leishmania Species Infections
Canadian Journal of Infectious Diseases, 1999 The understanding of the immunobiology of infections caused by the protozoan parasite leishmania is now extensive and has pinpointed the importance of T cell-mediated immunity.
Barbara Papadopoulou +2 more
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Sporozoite immunization: Innovative Translational Science to Support the Fight against malaria
Expert Review of Vaccines, 2023 Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened 247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in sub-Saharan Africa. A highly effective vaccine is urgently needed, especially
Thomas L. Richie +45 more
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Lessons Learned from Protective Immune Responses to Optimize Vaccines against Cryptosporidiosis
Pathogens, 2017 In developing countries, cryptosporidiosis causes moderate-to-severe diarrhea and kills thousands of infants and toddlers annually. Drinking and recreational water contaminated with Cryptosporidium spp.
Maxime W. Lemieux +2 more
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