Results 11 to 20 of about 11,003 (167)
Frontiers in Microbiology, 2022 A wide range of protozoan pathogens either transmitted by vectors (Plasmodium, Babesia, Leishmania and Trypanosoma), by contaminated food or water (Entamoeba and Giardia), or by sexual contact (Trichomonas) invade various organs in the body and cause ...
Lavoisier Akoolo +2 more
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The Stem Cell Revolution Revealing Protozoan Parasites’ Secrets and Paving the Way towards Vaccine Development [PDF]
Vaccines, 2021 Protozoan infections are leading causes of morbidity and mortality in humans and some of the most important neglected diseases in the world. Despite relentless efforts devoted to vaccine and drug development, adequate tools to treat and prevent most of ...
Alena Pance
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Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins [PDF]
Nature Communications, 2019 Abstract Intestinal and free-living protozoa, such as Giardia lamblia , express a dense coat of variant-specific surface proteins (VSPs) on trophozoites that protects the parasite inside the host’s intestine.
Serradell, Marianela +18 more
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Advances in understanding immunity to Toxoplasma gondii
Memorias do Instituto Oswaldo Cruz, 2009 Toxoplasma gondii is an important cause of clinical disease in fetuses, infants and immunocompromised patients. Since the discovery of T. gondii 100 years ago, this pathogen and the host's immune response to toxoplasmosis have been studied intensely ...
Elia D Tait, Christopher A Hunter
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Proteomics in Host-Protozoan Parasite Interactions and Development of Drug and Vaccine [PDF]
Advanced Pharmaceutical Bulletin, 2020 Protozoan parasites that cause disease in human (Leishmania, Plasmodium, Trypanosoma) reflect the balance of host defences and pathogen virulence at the time of invasion to the host. They have evolved a variety of strategies to subvert host defense functions.
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Parasite Carbohydrate Vaccines
Frontiers in Cellular and Infection Microbiology, 2017 Vaccination is an efficient means of combating infectious disease burden globally. However, routine vaccines for the world's major human parasitic diseases do not yet exist. Vaccines based on carbohydrate antigens are a viable option for parasite vaccine
Jonnel A. Jaurigue +3 more
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Pre-Erythrocytic Vaccines against Malaria
Vaccines, 2020 Malaria, caused by the protozoan Plasmodium, is a devastating disease with over 200 million new cases reported globally every year. Although immunization is arguably the best strategy to eliminate malaria, despite decades of research in this area we do ...
Camila Marques-da-Silva +2 more
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Field Application of a Subunit Vaccine against an Enteric Protozoan Disease
PLoS ONE, 2008 Coccidiosis is a major global veterinary health problem in intensively reared chickens. It is caused by apicomplexan parasites of the genus Eimeria.A subunit vaccine composed of purified antigens from the gametocytes of Eimeria maxima was used to stimulate the production and transfer of maternal antibodies between breeding hens and their hatchlings ...
Wallach, Michael G. +3 more
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Vaccination against the Protozoan Parasite Histomonas meleagridis Primes the Activation of Toll-like Receptors in Turkeys and Chickens Determined by a Set of Newly Developed Multiplex RT-qPCRs [PDF]
Vaccines, 2021 Histomonosis in turkeys and chickens is caused by the extracellular parasite Histomonas meleagridis, but the outcome of the disease varies depending on the host species. So far, studies on the immune response against histomonosis focus mainly on different traits of the adaptive immune system.
Taniya Mitra +4 more
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Recent Progress in Vaccine Development against Leishmania Species Infections
Canadian Journal of Infectious Diseases, 1999 The understanding of the immunobiology of infections caused by the protozoan parasite leishmania is now extensive and has pinpointed the importance of T cell-mediated immunity.
Barbara Papadopoulou +2 more
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