Revista da Sociedade Brasileira de Medicina Tropical, 2006 Os vírus linfotrópicos de células T humanas, quando integrados ao genoma da célula hospedeira, provírus, têm como marcador de replicação seu DNA proviral. A carga proviral parece ser um importante fator no desenvolvimento de patologias associadas a estes
Bruna Pedroso Tamegão-Lopes +3 more
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Veterinary Research, 2020 Cattle maintaining a low proviral load (LPL) status after bovine leukaemia virus (BLV) infection have been recognized as BLV controllers and non-transmitters to uninfected cattle in experimental and natural conditions.
Agustina Forletti +4 more
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Dolutegravir-based regimen maintains virological success in a patient with archived mutations to integrase inhibitors [PDF]
, 2017 no abstract ...
Falasca, Francesca +3 more
core +1 more source
Factors Associated with HIV-1 Proviral DNA Loads in Patients with Undetectable Plasma RNA Load
Journal of Korean Medical Science, 2009 To evaluate factors associated with human immunodeficiency virus type 1 (HIV-1) proviral DNA load, we conducted a cross-sectional study of 36 chronically HIV-1-infected individuals with undetectable plasma viral RNA. We used real-time polymerase chain reaction to determine the number of HIV-1 proviral DNA copies per 10(6) peripheral blood mononuclear ...
Choi, Jun Yong +11 more
openaire +3 more sources
Quantification of the virus-host interaction in human T lymphotropic virus I infection
Retrovirology, 2005 Background HTLV-I causes the disabling inflammatory disease HAM/TSP: there is no vaccine, no satisfactory treatment and no means of assessing the risk of disease or prognosis in infected people. Like many immunopathological diseases with a viral etiology
Taylor Graham P +6 more
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Immune compromise in HIV-1/HTLV-1 coinfection with paradoxical resolution of CD4 lymphocytosis during antiretroviral therapy: a case report [PDF]
, 2015 Human immunodeficiency virus type-1 (HIV-1) and human T lymphotropic virus type-1 (HTLV-1) infections have complex effects on adaptive immunity, with specific tropism for, but contrasting effects on, CD4 T lymphocytes: depletion with HIV-1, proliferation
Bangham, C +6 more
core +2 more sources
Revista Brasileira de Hematologia e Hemoterapia, 2008 As a high degree of homology exists between the proviral genomes of HTLV-I and HTLV-II, there is significant cross-reactivity. Therefore although detection of HTLV antibodies is characteristic of viral infection, it is not sufficient to confirm the ...
Bruna C. Arruda +6 more
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Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation [PDF]
, 2006 APOBEC3G and APOBEC3F restrict human immunodeficiency virus type 1 (HIV-1) replication in vitro through the induction of G!92A hypermutation; however, the relevance of this host antiviral strategy to clinical HIV-1 is currently not known.
Pace, C. +6 more
core +2 more sources
HTLV-I proviral load in Argentinean subjects with indeterminate western blot patterns [PDF]
Retrovirology, 2011 Methodology A total of 87 indeterminate WB samples (HTLV blot 2.4 assayGenelabs Diagnostics-) were studied over a 10 year period referred from the Blood Bank at Garrahan Hospital (n=83) and from the Virology Unit at Muniz Hospital (n=4). HTLV-I and –II tax and pol proviral sequences were amplified by in-house nested PCR assays. HTLV-I pVL was estimated
Sen Luisa +7 more
openaire +2 more sources
Evaluation of HTLV-1 activity in HAM/TSP patients using proviral load and Tax mRNA expression after In Vitro lymphocyte activation [PDF]
Iranian Journal of Basic Medical Sciences, 2014 Objective(s):HTLV-1 is the first human retrovirus that has been recognized and is associated with HAM/TSP and ATLL. Studies have shown that less than five percent of HTLV-1 infected carriers develop HAM/TSP or ATLL and about ninety-five percent remain ...
Atefeh Yari +6 more
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