Results 101 to 110 of about 16,807 (206)

Outbreak of Porcine Reproductive and Respiratory Syndrome Virus 1 in Taiwan

Viruses, 2020
Porcine reproductive and respiratory syndrome (PRRS) causes significant economic losses in the swine industry worldwide. The PRRS virus (PRRSV) can be divided into two species, PRRSV 1 (European) and PRRSV 2 (North American).
Wei-Hao Lin, Kraijak Kaewprom, Sheng-Yuan Wang, Chuen-Fu Lin, Cheng-Yao Yang, Ming-Tang Chiou, Chao-Nan Lin   +6 more
doaj   +1 more source

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren, Yan Wang, Haoyuan Ma, Jialiang Xie, Jianyou Jin, Rumeng Tian, Hao Yu, Xu Gao, Nanhua Chen   +8 more
wiley   +1 more source

CD163 and pAPN double-knockout pigs are resistant to PRRSV and TGEV and exhibit decreased susceptibility to PDCoV while maintaining normal production performance

eLife, 2020
Porcine reproductive and respiratory syndrome virus (PRRSV) and transmissible gastroenteritis virus (TGEV) are two highly infectious and lethal viruses causing major economic losses to pig production.
Kui Xu, Yanrong Zhou, Y. Mu, Zhiguo Liu, Shaohua Hou, Yujian Xiong, L. Fang, Changli Ge, Yinghui Wei, Xiuling Zhang, Changjiang Xu, Jingjing Che, Ziyao Fan, Guangming Xiang, Jian-qun Guo, Haitao Shang, Hua Li, Shaobo Xiao, Julang Li, Kui-Lin Li   +19 more
semanticscholar   +1 more source

A Novel In‐Cell ELISA With Superior Sensitivity and Specificity for the Detection of African Swine Fever Virus‐Specific IgM and IgG Antibodies

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a high‐profile transboundary animal disease caused by ASF virus (ASFV), imposes a devastating impact on the global swine industry. Given that vaccines are still under development, including field evaluations, early detection of ASFV is crucial for effective disease control and mitigation.
Ping Wu, Aric J. McDaniel, Yelitza Y. Rodríguez, Vivian O’Donnell, Wei Jia, Nan-hua Chen   +5 more
wiley   +1 more source

Novel Duck Orthoreovirus Induces Ferroptosis in HD11 Cells by Hijacking Cellular Iron Metabolism and Promoting Iron Accumulation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Novel duck orthoreovirus (NDRV) infection induces severe splenic necrosis in ducks, resulting in a cascade of detrimental consequences, including immunosuppression, secondary infections, and diminished vaccine efficacy. Avian orthoreovirus (ARV) exhibits high tropism for macrophages, with splenic macrophages being identified as the primary target cells
Hongzhi Wang, Di Lei, Chenchen Jiang, Boyi Xu, Yi Tang, Rendong Fang, Zongfu Wu   +6 more
wiley   +1 more source

TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling

PLoS Pathogens, 2020
Triggering receptor expressed on myeloid cells 2 (TREM2) serves as an anti-inflammatory receptor, negatively regulating the innate immune response. TREM2 is mainly expressed on dendritic cells and macrophages, the target cells of porcine reproductive and
Zhenbang Zhu, Xiaoxiao Zhang, Wenjuan Dong, Xiaoying Wang, Sheng-Dong He, Hui Zhang, Xun Wang, Ruiping Wei, Yaosheng Chen, Xiaohong Liu, Chunhe Guo   +10 more
semanticscholar   +1 more source

Expanding Horizons: Next‐Generation and Interdisciplinary Advances in the Applications of Extracellular Vesicles

Journal of Extracellular Biology, Volume 4, Issue 12, December 2025.
ABSTRACT Extracellular vesicles (EVs) are increasingly recognized as universal mediators of communication in nature across all domains of life and as versatile tools with roles spanning a wide range of industries. Although EVs have been extensively studied in biomedicine, mainly in diagnostic and nanotherapy of cancer and neurodegenerative diseases ...
Esperanza González, Juan Manuel Falcón‐Pérez   +1 more
wiley   +1 more source

The GP2a 91/97/98 amino acid substitutions play critical roles in determining PRRSV tropism and infectivity but do not affect immune responses

Journal of Virology
Porcine reproductive and respiratory syndrome virus (PRRSV) isolates share a restricted cellular tropism. Marc-145 cells derived from African green monkey are one of the few cell lines supporting PRRSV propagation in vitro and are commonly used for PRRS ...
Ming Qiu, Shuai Li, Shubin Li, Zhe Sun, Hong Lin, Shuai Yang, Meng Cui, Yuejia Qiu, Wenhao Qi, Xiuling Yu, Shaobin Shang, Kegong Tian, François Meurens, Jianzhong Zhu, Nanhua Chen   +14 more
doaj   +1 more source

Genetic Diversity of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) From 1996 to 2017 in China

Frontiers in Microbiology, 2020
Porcine reproductive and respiratory syndrome (PRRS) is one of the most devastating diseases of the global swine industry. The causative agent porcine reproductive and respiratory syndrome virus (PRRSV) was first isolated in China in 1996 and has evolved
Yi-feng Jiang, Guo-xin Li, Lingxue Yu, Li-wei Li, Yu-jiao Zhang, Yanjun Zhou, Wu Tong, Changlong Liu, Fei Gao, G. Tong   +9 more
semanticscholar   +1 more source

Simulation model to estimate the burden of disease due to hepatitis E virus in Dutch pig meat and cost‐effectiveness of control measures

Risk Analysis, Volume 45, Issue 12, Page 4272-4288, December 2025.
Abstract Hepatitis E virus (HEV) can lead to liver disease in humans. In the Netherlands, the consumption of pig meat is thought to be the main contributor to the total burden of disease caused by HEV. In this study, the number of cases and lost disability‐adjusted‐life‐years (DALYs) due to HEV in pig meat were estimated by simulating HEV through the ...
M. Focker, C. P. A. van Wagenberg, M. A. P. M. van Asseldonk, I. L. A. Boxman, R. W. Hakze ‐ van der Honing, E. D. van Asselt   +5 more
wiley   +1 more source