Results 101 to 110 of about 14,046 (214)

A bacterial exotoxin-triggered plant immune response restricts pathogen growth

Cell Reports
Summary: For optimal growth and development, hosts must promote healthy symbiotic interactions while restricting pathogens. To ask whether hosts can distinguish phylogenetically similar pathogens and beneficial bacteria, we used two closely related plant
David Thoms, Melissa Y. Chen, Yang Liu, Leah Fulton, Youqing Luo, Daniel E. Hiott, Siyu Song, Zayda Morales Moreira, Nicole R. Wang, Diego Zorio, Martin Rejzek, Ryan Potter, Philip Carella, Cara H. Haney   +13 more
doaj   +1 more source

Molecular Study of the Prevalence of Exotoxin A and Alginate Gene in Pseudomonas Aeruginosa Isolates in Burn Wounds Samples

مجله دانشکده پزشکی اصفهان, 2017
Background: Pseudomonas aeruginosa is one of the major nosocomial pathogens with a vast antibiotic resistance and great ability in adaptation with environment.
Seyed Hamidreza Mortazavi, Mehdi Ghaderi, Mitra Hemmati, Siavash Vaziri, Mohsen Azizi, Mahsa Kashef, Kamal Ahmadi   +6 more
doaj  

Novel Anti-Mesothelin Nanobodies and Recombinant Immunotoxins with Pseudomonas Exotoxin Catalytic Domain for Cancer Therapeutics. [PDF]

Mol Cells, 2023
Nguyen MQ, Kim DH, Shim HJ, Ta HKK, Vu TL, Nguyen TKO, Lim JC, Choe H.   +7 more
europepmc   +1 more source

New and emerging therapeutic options for malignant pleural mesothelioma: review of early clinical trials. [PDF]

, 2015
Malignant pleural mesothelioma (MPM) is a rare tumor that is challenging to control. Despite some benefit from using the multimodality-approach (surgery, combination chemotherapy and radiation), survival remains poor. However, current research produced a
Cameron, Robert B, Kotova, Svetlana, Wong, Raymond M   +2 more
core   +2 more sources

Isolation Virulence genes ETA, OPrL, gyrB in Pseudomonas aeruginosa clinical samples from hospitals in Kerman by Multiplex-PCR [PDF]

, 2016
زمینه و هدف: سودوموناس آئروژینوزا یک پاتوژن فرصت طلب و عامل عفونت های بیمارستانی و مرگ و میر به خصوص در بیماران با ضعف سیستم ایمنی می باشد و مقاومت ذاتی به مواد ضد میکروبی منجر به مشکلاتی در درمان عفونت های آن می شود.
Amini, K., Kamali, A.
core   +1 more source

Gene expression profiling identifies IL-13 receptor alpha 2 chain as a therapeutic target in prostate tumor cells overexpressing adrenomedullin [PDF]

, 2005
Human adrenomedullin (AM) is a 52 amino acid peptide, which shares homology with the calcitonin gene-related peptide. Overexpression of AM in the prostate carcinoma cell line PC-3 results in growth inhibition with a 20% (for human AM) and 35% (for rat AM)
Abasolo, I. (Ibane), Calvo, A. (Alfonso), Gonzalez-Moreno, O. (Óscar), Green, J.E. (Jeffrey E.), Joshi, B.H. (Bharat H.), Leland, P. (Pamela), Montuenga-Badia, L.M. (Luis M.), Puri, R.K. (Raj K.), Wang, Z. (Zhou)   +8 more
core   +1 more source

Pseudomonas aeruginosa exotoxin A as a novel allergen induced Non-TH2 inflammation in a murine model of steroid-insensitive asthma

Heliyon
Background: Despite the immediate in vivo occurrence of anaphylactic and allergic reactions following treatment with Pseudomonas aeruginosa exotoxin A (PEA)-based immunotoxins, the immunological role of PEA in asthma pathogenesis remains unclear ...
Huancheng Xie, Linmei Li, Yuhe Guo, Linghui Zhou, Linyi Ma, Andong He, He Lai, Ying He, Yongping Liu, Huifang Chen, Liping Luo, Yuyi Huang, Xiangyin Sha, Huanping Zhang, Jie Yan, Qingling Zhang, Ailin Tao   +16 more
doaj   +1 more source

Tests on medical microbiology [PDF]

, 2013
МИКРОБИОЛОГИЯ ...
Generalov, I. I., Zheleznyak, N. V.
core  

Molecular Detection of tox A Gene in Multidrug Resistance Pseudomonas aeruginosa Isolated from Burn Infections

Medical Journal of Babylon
Background: Exotoxin A (ExoA) is the most widespread and toxic virulence agent among pathogenic Pseudomonas aeruginosa species that acquire adenosine diphosphate-ribosyltransferase activity belonging to the class of exotoxins secreted by pathogenic ...
Zahraa Hamza Merza, Rabab Omran
doaj   +1 more source

Reduced cytotoxicity by mutation of lysine 590 of Pseudomonas exotoxin can be restored in an optimized, lysine-free immunotoxin. [PDF]

Immunother Adv, 2022
Ammon A, Mellenthin L, Emmerich C, Naschberger E, Stürzl M, Mackensen A, Müller F, Müller F.   +7 more
europepmc   +1 more source