Results 81 to 90 of about 14,191 (208)

Chimeric carrier proteins for targeted delivery of tumor antigens to professional antigen presenting cells [PDF]

, 2007
Tumor-specific T lymphocytes can be regarded as a highly effective mechanism for tumor rejection. A substantial number of T-cell defined tumor antigens including mutated oncoproteins and differentiation antigens have been identified.
Kursar, Mischo, Mittrücker, Hans-Willi, Rohrbach, Florian, Wels, Winfried S., Weth, Robert   +4 more
core  

Action Mechanism of Essential Oils or Their Components Against Pathogenic Bacteria: Literature Review

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Essential oils (EOs), derived from medicinal and aromatic plants, are natural mixtures of volatile, oily compounds with varying compositions and antibacterial mechanisms. Understanding the mechanisms of EOs and their components (EOCs) is essential for predicting their impacts on various microbes and their interactions with antibiotics.
Mohamed A. El-Sakhawy, Abd El Raheim Mohammed Donia, Tawfiq N. Juraybi, Abeer Ali El-Sherbiny Ateya, Wadah Osman, Amr A. Abd-Elghany, Mohamed Mostafa Soliman, Abdel Naser A. Kobisi, Mohamed A. Balah, Shweta Negi   +9 more
wiley   +1 more source

DETECTION OF ExoT GENE IN LOCAL ISOLATES OF PSEUDOMONAS AUROGINOSA IN A SAMPLE OF BURN INFECTION

The Iraqi Journal of Medical Sciences, 2018
Background: Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic microorganism that requires damaged mucus membranes and epithelial tissues to cause acute infections. It had been stated that P.
Rana A. Hanoon, Ibtisam G. Auda, Ismail H. Aziz   +2 more
doaj   +6 more sources

Bacillus anthracis edema factor substrate specificity: evidence for new modes of action [PDF]

, 2012
Since the isolation of Bacillus anthracis exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only.
Agrawal, Altaweel, Basler, Bauche, Bell, Benson, Beste, Bock, Bond, Boyd, Bradley, Brown, Burhenne, Carbonetti, Carbonetti, Carson-Walter, Casteel, Christensen, Christensen, Confer, Copsel, Crawford, Crowe, Cunningham, Dalkas, Defer, Deuquet, Ding, Drum, Duesbery, Feld, Firoved, Friedlander, Fu, Fukuhara, Gaion, Gille, Gordon, Göttle, Hammerschmidt, He, Helfman, Hong, Ivarsson, Jernigan, Johnson, Katayama, Katayama, Kaupp, Kintzer, Klimpel, Laine, Larabee, Larabee, Leppla, Liu, Martin Göttle, McDonough, Milne, Mogridge, Mogridge, Newton, Newton, Newton, Newton, Newton, Oncu, O´Brien, Park, Petosa, Pezard, Postea, Puhar, Roland Seifert, Santelli, Scobie, Scobie, Scorpio, Shapiro, Shen, Shirshev, Soelaiman, Stefan Dove, Sun, Tamayo, Taylor, Taylor, Tesmer, Thomas, Tournier, Vitale, Vitale, Vojtova, Yeager, Zong   +94 more
core   +2 more sources

Mechanism of GSDMD in the Pathogenesis of Pasteurella multocida PmCQ2

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Pasteurella multocida serotype A (PmCQ2), a Gram‐negative zoonotic pathogen, causes severe respiratory disease in a variety of domestic and wild animals, leading to high morbidity and mortality and substantial agricultural economic losses. Pyroptosis, a gasdermin‐mediated programmed cell death mechanism, facilitates pathogen clearance but exacerbates ...
Qingqing Yang, Wei Wang, Xin Shen, Yi Lu, Jiajia Zheng, Jinrong Ran, Xuefeng Cao, Rendong Fang, Zongfu Wu   +8 more
wiley   +1 more source

Use of single-chain antibody derivatives for targeted drug delivery [PDF]

, 2016
Single-chain antibodies (scFvs), which contain only the variable domains of full-length antibodies, are relatively small molecules that can be used for selective drug delivery.
Ahmadzadeh, V., Erfani-Moghadam, V., Jaliani, H.Z., Khalili, M., Safdari, Y., Zarei, V.   +5 more
core   +1 more source

Purification and Characterization of Pseudomonas aeruginosa Exotoxin [PDF]

Infection and Immunity, 1974
A trypsin-sensitive, heat-labile exotoxin of Pseudomonas aeruginosa strain P-A-103 has been purified by a procedure that includes membrane ultrafiltration, hydroxylapatite chromatography, ion-exchange cellulose chromatography, and gel filtration chromatography.
openaire   +2 more sources

Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple models, secondary necrosis occurred regardless of gasdermin E presence, challenging prior claims and redefining the understanding of how apoptotic cells ...
Shubhangi Gavali, Francesca Maremonti, Wulf Tonnus, Florian Gembardt, Marlena Nastassja Schlecht, Karolin Flade, Anne von Mässenhausen, Stephen W. G. Tait, Stefan R. Bornstein, Andreas Linkermann   +9 more
wiley   +1 more source

Quorum sensing communication between bacteria and human cells: signals, targets, and functions [PDF]

, 2014
Both direct and long-range interactions between pathogenic Pseudomonas aeruginosa bacteria and their eukaryotic hosts are important in the outcome of infections. For cell-to-cell communication, these bacteria employ the quorum sensing (QS) system to pass
Angelika Holm, Elena Vikström
core   +2 more sources

Phenotypic and Genotypic Profile of Enterobacteriaceae Isolated at a Teaching Hospital in Ghana

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study identified a significant prevalence of antimicrobial resistance determinants within Enterobacteriaceae isolates, with particular emphasis on those producing extended‐spectrum β‐lactamases (ESBL). These isolates harbored diverse antibiotic resistance genes (ARGs), plasmid replicons, and virulence factors (VFs), highlighting the imperative for
Bismark Donkor, Richael Odarkor Mills, Philimon Mwintige, Alberta Bedford Moses, Abigail Asmah Brown, Faustina Halm‐Lai, Oheneba Charles Kofi Hagan   +6 more
wiley   +1 more source