Results 81 to 90 of about 113,972,927 (185)

THE CREATION OF A DOUBLE HYBRID CELL LINE SECRETING A BIFUNCTIONAL ANTIBODY MOLECULE WITH ONE BINDING SITE RECOGNIZING A MELANOMA ASSOCIATED ANTIGEN AND THE OTHER PSEUDOMONAS EXOTOXIN A

, 1987
Hybrid hybridomas (quadromas) which produced antibody of mixed parentage were isolated through the fusion of two biochemically deficient hybridoma lines.
Bordonaro, John Paul
core   +1 more source

Novel Anti-Mesothelin Nanobodies and Recombinant Immunotoxins with Pseudomonas Exotoxin Catalytic Domain for Cancer Therapeutics. [PDF]

Mol Cells, 2023
Nguyen MQ, Kim DH, Shim HJ, Ta HKK, Vu TL, Nguyen TKO, Lim JC, Choe H.   +7 more
europepmc   +1 more source

The use of topical sodium hypochlorite in the management of Pseudomonas aeruginosa burn wound infection [PDF]

, 2011
The aim of the study is: 1. To undertake a meta-analysis of Pseudomonas aeruginosa burn wound infection. 2. To undertake a retrospective audit of Pseudomonas aeruginosa burn wound infection at the Red Cross War Memorial Children's Hospital. 3.
Coetzee, Emile
core   +1 more source

Molecular Study of the Prevalence of Exotoxin A and Alginate Gene in Pseudomonas Aeruginosa Isolates in Burn Wounds Samples

مجله دانشکده پزشکی اصفهان, 2017
Background: Pseudomonas aeruginosa is one of the major nosocomial pathogens with a vast antibiotic resistance and great ability in adaptation with environment.
Seyed Hamidreza Mortazavi, Mehdi Ghaderi, Mitra Hemmati, Siavash Vaziri, Mohsen Azizi, Mahsa Kashef, Kamal Ahmadi   +6 more
doaj  

A bacterial exotoxin-triggered plant immune response restricts pathogen growth

Cell Reports
Summary: For optimal growth and development, hosts must promote healthy symbiotic interactions while restricting pathogens. To ask whether hosts can distinguish phylogenetically similar pathogens and beneficial bacteria, we used two closely related plant
David Thoms, Melissa Y. Chen, Yang Liu, Leah Fulton, Youqing Luo, Daniel E. Hiott, Siyu Song, Zayda Morales Moreira, Nicole R. Wang, Diego Zorio, Martin Rejzek, Ryan Potter, Philip Carella, Cara H. Haney   +13 more
doaj   +1 more source

Molecular detection of virulence factors and biofilm formation in Pseudomonas aeruginosa obtained from different clinical specimens in Bandar Abbas

Iranian Journal of Microbiology, 2019
Background and Objectives: Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen. The presence of several virulence factors such as exotoxin and exoenzyme genes and biofilm may contribute to its pathogenicity.
Nima Bahador, Saeed Shoja, Foroogh Faridi, Banafsheh Dozandeh-Mobarrez, Fatemeh Izadpanah Qeshmi, Sedigheh Javadpour, Sedigheh Mokhtary   +6 more
doaj   +1 more source

DEVELOPMENT OF THE VACCINE BASED ON THE RECOMBINANT ANTIGENS OF PSEUDOMONAS AERUGINOSA

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. The aim is obtaining, investigation and selection of recombinant antigens for inclusion theirs into the against Pseudomonas vaccine. Materials and methods. The genes encoding of the outer  membrane proteins F, L and I and Exotoxin A were synthesized
N. A. Mihailova, E. M. Zimina, A. V. Soldatenkova, A. A. Kaloshin   +3 more
doaj   +1 more source

Enhanced cytotoxicity of a Pseudomonas Exotoxin A based immunotoxin against prostate cancer by addition of the endosomal escape enhancer SO1861. [PDF]

Front Pharmacol, 2023
Masilamani AP, Huber N, Nagl C, Dettmer-Monaco V, Monaco G, Wolf I, Schultze-Seemann S, Taromi S, Gratzke C, Fuchs H, Wolf P.   +10 more
europepmc   +1 more source

Biosynthetic incorporation of 7-azatryptophan into the catalytic domain of Pseudomonas aeruginosa exotoxin A.

, 1997
Pseudomonas aeruginosa exotoxin A (ETA), is a mono-ADP-ribosyl transferase (ADPRT) that catalyzes the transfer of the ADP-ribosyl moiety of NAD$\sp+$ to eukaryotic elongation factor-2 (eEF-2).
Yeh, Foo-Lim
core   +1 more source

A dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin A and diphtheria toxin.

PLoS ONE, 2010
Diphtheria toxin (DT), Pseudomonas aeruginosa Exotoxin A (ETA) and cholix toxin from Vibrio cholerae share the same mechanism of toxicity; these enzymes ADP-rybosylate elongation factor-2 (EF-2) on a modified histidine residue called diphthamide, leading
Vincent Roy, Karim Ghani, Manuel Caruso
doaj   +1 more source