Results 41 to 50 of about 8,117 (224)

Long-term Cre-mediated retrograde tagging of neurons using a novel recombinant pseudorabies virus [PDF]

open access: yes, 2014
Brain regions contain diverse populations of neurons that project to different long-range targets. The study of these subpopulations in circuit function and behavior requires a toolkit to characterize and manipulate their activity in vivo.
Anthony M. Zador   +4 more
core   +2 more sources

Comprehensive evaluation of the safety and immunogenicity of a gene-deleted variant pseudorabies virus attenuated vaccine

open access: yesVeterinary Research, 2022
Pseudorabies virus (PRV) variant infections have caused a substantial economic impact on swine production in the absence of new powerful candidate vaccines.
Ling Li   +12 more
doaj   +1 more source

Huaier Polysaccharide Interrupts PRV Infection via Reducing Virus Adsorption and Entry

open access: yesViruses, 2022
A pseudorabies virus (PRV) novel virulent variant outbreak occurred in China in 2011. However, little is known about PRV prevention and treatment. Huaier polysaccharide has been used to treat some solid cancers, although its antiviral activity has not ...
Changchao Huan   +6 more
doaj   +1 more source

Characterization of Pseudorabies Virus (PrV) Cleavage-Encapsidation Proteins and Functional Complementation of PrV pUL32 by the Homologous Protein of Herpes Simplex Virus Type 1 [PDF]

open access: yesJournal of Virology, 2009
ABSTRACT Cleavage and encapsidation of newly replicated herpes simplex virus type 1 (HSV-1) DNA requires several essential viral gene products that are conserved in sequence within the Herpesviridae . However, conservation of function has not been analyzed in greater detail. For functional characterization
Walter, Fuchs   +4 more
openaire   +2 more sources

The effects of viral load on pseudorabies virus gene expression [PDF]

open access: yes, 2010
Background Herpesvirus genes are classified into distinct kinetic groups on the basis of their expression dynamics during lytic growth of the virus in cultured cells at a high, typically 10 plaque-forming units/cell multiplicity of infection (
Judit S Tóth   +3 more
core   +2 more sources

Guanylate-binding protein 1 inhibits nuclear delivery of pseudorabies virus by disrupting structure of actin filaments

open access: yesVeterinary Research, 2023
The alphaherpesvirus pseudorabies virus (PRV) is the causative agent of pseudorabies, responsible for severe economic losses to the swine industry worldwide.
Xiaohua Zhang   +7 more
doaj   +1 more source

Ex vivo infection of human embryonic spinal cord neurons prior to transplantation into adult mouse cord [PDF]

open access: yes, 2010
Background Genetically modified pseudorabies virus (Prv) proved suitable for the delivery of foreign genes to rodent embryonic neurons ex vivo and maintaining foreign gene expression after transplantation into spinal cord in our earlier study.
Gábor Márton   +7 more
core   +2 more sources

Epidemiological investigation, determination of related factors, and spatial-temporal cluster analysis of wild type pseudorabies virus seroprevalence in China during 2022

open access: yesFrontiers in Veterinary Science, 2023
IntroductionPseudorabies virus (PRV) is a linear DNA virus with a double-stranded structure, capable of infecting a diverse array of animal species, including humans.
Wenchao Gao   +40 more
doaj   +1 more source

Cellular gene expression survey of PseudoRabies Virus (PRV) infected Human Embryonic Kidney cells (HEK-293) [PDF]

open access: yesVeterinary Research, 2006
Pseudorabies virus (PRV) is an alpha herpesvirus that causes Aujezsky disease in the pig. To characterize the impact of PRV infection on cellular expression, we used microarrays consisting of 9850 oligonucleotides corresponding to human genes and examined the expression levels of mRNA isolated 0.5, 3, 6, and 9 h post infection (hpi) from cultures of ...
Blanchard, Yannick   +5 more
openaire   +4 more sources

Pseudorabies Virus: From Pathogenesis to Prevention Strategies

open access: yesViruses, 2022
Pseudorabies (PR), also called Aujeszky’s disease (AD), is a highly infectious viral disease which is caused by pseudorabies virus (PRV). It has been nearly 200 years since the first PR case occurred.
Hui-Hua Zheng   +3 more
doaj   +1 more source

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