Results 51 to 60 of about 8,243 (225)

Structures of pseudorabies virus capsids

open access: yesNature Communications, 2022
Pseudorabies virus (PRV) is a major etiological agent of swine infectious diseases responsible for significant economic losses in the swine industry. The authors report the structures of the PRV A-capsid and C-capsid, shedding light on PRV’s assembly ...
Guosong Wang   +18 more
doaj   +1 more source

Pseudorabies Virus: From Pathogenesis to Prevention Strategies

open access: yesViruses, 2022
Pseudorabies (PR), also called Aujeszky’s disease (AD), is a highly infectious viral disease which is caused by pseudorabies virus (PRV). It has been nearly 200 years since the first PR case occurred.
Hui-Hua Zheng   +3 more
doaj   +1 more source

A novel inactivated gE/gI deleted pseudorabies virus (PRV) vaccine completely protects pigs from an emerged variant PRV challenge

open access: yesVirus Research, 2015
A highly virulent and antigenic variant of pseudorabies virus (PRV) broke out in China at the end of 2011 and caused great economic loss in the pig industry. In this study, an infectious bacterial artificial chromosome (BAC) clone containing the full-length genome of the emerged variant PRV ZJ01 strain was generated.
Zhenqing, Gu   +7 more
openaire   +2 more sources

Multi-Platform Sequencing Approach Reveals a Novel Transcriptome Profile in Pseudorabies Virus [PDF]

open access: yes, 2018
Third-generation sequencing is an emerging technology that is capable of solving several problems that earlier approaches were not able to, including the identification of transcripts isoforms and overlapping transcripts. In this study, we used long-read
Boldogkői, Zsolt   +5 more
core   +5 more sources

Herpesvirus-mediated delivery of a genetically encoded fluorescent Ca2+ sensor to canine cardiomyocytes [PDF]

open access: yes, 2009
We report the development and application of a pseudorabies virus-based system for delivery of troponeon, a fluorescent Ca2+ sensor to adult canine cardiomyocytes.
Boldogkői, Zsolt   +12 more
core   +4 more sources

The Role of Latency-Associated Transcripts in the Latent Infection of Pseudorabies Virus

open access: yesViruses, 2022
Pseudorabies virus (PRV) can cause neurological, respiratory, and reproductive diseases in pigs and establish lifelong latent infection in the peripheral nervous system (PNS).
Jiahuan Deng   +4 more
doaj   +1 more source

Interferon alpha suppresses alphaherpesvirus immediate early protein levels in sensory neurons, leading to the establishment of a latent infection [PDF]

open access: yes, 2010
Alphaherpesviruses are a subfamily of the herpesviruses containing closely related human and animal pathogens, including human herpes simplex virus (HSV-1) and porcine pseudorabies virus (PRV)
De Regge, Nick   +4 more
core  

Droplet Digital CRISPR for Nucleic Acid Detection

open access: yesAdvanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang   +4 more
wiley   +1 more source

Expression of Pseudorabies Virus (PRV) Glycoproteins gB, gC and gD using Bacterial Expression System [PDF]

open access: yesInternational Journal of Industrial Entomology, 2011
The Pseudorabies (PR), also called Aujeszky`s disease (AD), is an infectious viral disease caused by an alpha herpes virus and has domestic and wild pigs, as well as a wide range of domestic and wild animals, as the natural host. Pseudorabies virus (PRV) virions contain several envelope glycoproteins. Among them, gB, gC and gD are regarded as the major
Bit-Na-Rae Yun   +4 more
openaire   +1 more source

Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions

open access: yesBiotechnology Progress, EarlyView.
Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal   +5 more
wiley   +1 more source

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