Results 101 to 110 of about 1,806,143 (218)

Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA.

open access: yes, 1999
Pseudouridine (Psi) residues were localized in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (UsnRNAs) by using the chemical mapping method. In contrast to vertebrate UsnRNAs, S.
Massenet, S   +9 more
core   +1 more source

iPseU-NCP: Identifying RNA pseudouridine sites using random forest and NCP-encoded features

open access: yesBMC Genomics, 2019
Background Pseudouridine modification is most commonly found among various kinds of RNA modification occurred in both prokaryotes and eukaryotes. This biochemical event has been proved to occur in multiple types of RNAs, including rRNA, mRNA, tRNA, and ...
Thanh-Hoang Nguyen-Vo   +5 more
doaj   +1 more source

Candidate mRNA Pseudouridine Sites Identified in Multiple Samples.

open access: yes, 2014
List of the 24 candidate mRNA pseudouridine sites from ψ-seq analysis of yeast RNA that were independently identified in multiple experiments from log phase and heat shock RNA samples.
Patrick O. Brown (5555)   +2 more
core   +1 more source

Steroid receptor RNA activator (SRA) modification by the human pseudouridine synthase 1 (hPus1p): RNA binding, activity, and atomic model.

open access: yesPLoS ONE, 2014
The most abundant of the modified nucleosides, and once considered as the "fifth" nucleotide in RNA, is pseudouridine, which results from the action of pseudouridine synthases.
Tiphaine Huet   +3 more
doaj   +1 more source

Structure and function of the pseudouridine 5’-monophosphate glycosylase PUMY from Arabidopsis thaliana

open access: yesRNA Biology
Pseudouridine is a noncanonical C-nucleoside containing a C-C glycosidic linkage between uracil and ribose. In the two-step degradation of pseudouridine, pseudouridine 5’-monophosphate glycosylase (PUMY) is responsible for the second step and catalyses ...
Jeongyun Lee   +2 more
doaj   +1 more source

The Pseudouridine Synthases Proceed through a Glycal Intermediate

open access: yes, 2016
The pseudouridine synthases isomerize (U) in RNA to pseudouridine (Ψ), and the mechanism that they follow has long been a question of interest. The recent elucidation of a product of the mechanistic probe 5-fluorouridine that had been epimerized to the ...
Govardhan Reddy Veerareddygari (2834174)   +2 more
core   +1 more source

OsPPG encodes a pseudouridine-5′-phosphate glycosidase and regulates rice spikelet development

open access: yesCrop Journal
Florets are the basic structural units of spikelets, and their morphogenesis determines the yield and quality of rice grains. However, whether and how pseudouridine-5′-phosphate glycosidase participates in rice spikelet development remains an open ...
Rui Chen   +11 more
doaj   +1 more source

[Assessment of the Concentration of Pseudouridine in Urine As An Early Indicator of a Malignant Process]

open access: yes, 1990
The catabolism of tRNA gives rise to modified nucleosides, among which pseudouridine, which are excreted in urine. An increased cell turnover is associated with an enhanced excretion of these products.
Senden, D.   +2 more
core  

Substrate binding and catalysis by the pseudouridine synthases RluA and TruB [PDF]

open access: yes, 2012
xi, 122 leaves : ill. (some col.) ; 29 cmPseudouridine is the most common RNA modification found in all forms of life. The exact role pseudouridines play in the cell is still relatively unknown.
Keffer-Wilkes, Laura C.
core  

Quantitative mapping of pseudouridines in bacterial RNA

open access: yesNature Communications
Abstract RNA pseudouridylation is one of the most prevalent post-transcriptional modifications, occurring universally across all organisms. Although pseudouridines have been extensively studied in bacterial tRNAs and rRNAs, their presence and role in bacterial mRNA remain poorly characterized.
Shikha Sharma   +6 more
openaire   +3 more sources

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