Results 81 to 90 of about 1,720,439 (181)

OsPPG encodes a pseudouridine-5′-phosphate glycosidase and regulates rice spikelet development

Crop Journal
Florets are the basic structural units of spikelets, and their morphogenesis determines the yield and quality of rice grains. However, whether and how pseudouridine-5′-phosphate glycosidase participates in rice spikelet development remains an open ...
Rui Chen, Dagang Tian, Yarong Lin, Jiaqing Huang, Qinqin Yang, Yupei Li, Huaqing Liu, Shaohua Yang, Jingyang Chen, Shufen Zhou, Feng Wang, Shubiao Zhang   +11 more
doaj   +1 more source

Quantitative mapping of pseudouridines in bacterial RNA

Nature Communications
Abstract RNA pseudouridylation is one of the most prevalent post-transcriptional modifications, occurring universally across all organisms. Although pseudouridines have been extensively studied in bacterial tRNAs and rRNAs, their presence and role in bacterial mRNA remain poorly characterized.
Shikha Sharma, Brendan Woodworth, Bin Yang, Ning Duan, Mannuku Pheko, Niki Moutsopoulos, Akintunde Emiola   +6 more
openaire   +3 more sources

Pseudouridine Residues as Substrates for Serum Ribonucleases

RNA
In clinical uses, RNA must maintain its integrity in serum that contains ribonucleases (RNases), especially RNase 1, which is a human homolog of RNase A. These omnipresent enzymes catalyze the cleavage of the P–O5′′ bond on the 3′ side of pyrimidine residues. Pseudouridine (Ψ) is the most abundant modified nucleoside in natural RNA. The substitution of
Clair S. Gutierrez, Bjarne Silkenath, Volga Kojasoy, Jaroslaw A. Pich, Daniel C. Lim, Ronald T. Raines   +5 more
openaire   +2 more sources

Implications of RNA pseudouridylation for cancer biology and therapeutics: a narrative review

Journal of Translational Medicine
Background Pseudouridine (Ψ), a C5-glycoside isomer of uridine, stands as one of the most prevalent RNA modifications in all RNA types. Distinguishing from the C-N bond linking uridine to ribose, the link between Ψ and ribose is a C-C bond, endowing Ψ ...
Hanyi Ding, Na Liu, Yan Wang, Sofia Abdulkadir Adam, Jie Jin, Weiying Feng, Jie Sun   +6 more
doaj   +1 more source

Pseudouridine in mRNA [PDF]

, 2015
Guowei Wu, Chao Huang, Yi-Tao Yu
openaire   +1 more source

Loss of Pseudouridine Synthases in the RluA Family Causes Hypersensitive Nociception in Drosophila

G3: Genes, Genomes, Genetics, 2020
Wan Song, Susanne Ressl, W. Daniel Tracey   +2 more
doaj   +1 more source

Integrative Genomic Analysis Reveals Pseudouridine Modification-Related Gene Signatures Associated With Prognosis and Therapeutic Response Patterns in Hepatocellular Carcinoma. [PDF]

Int J Genomics
Gan Z, Fan T, Wang W, Qiao X, Zhao M.
europepmc   +1 more source

Quantitative RNA pseudouridine landscape reveals dynamic modification patterns and evolutionary conservation across bacterial species. [PDF]

Elife
Xu L, Shen S, Zhang Y, Guo Z, Lu B, Huang J, Li R, Shen Y, Zhang LS, Deng X.   +9 more
europepmc   +1 more source

Multimodal profiling reveals cell type-specific pseudouridine modification and density-dependent translational regulation. [PDF]

Nucleic Acids Res
McCormick CA, Meseonznik M, Qiu Y, Fanari O, Goyal P, Thomas M, Shokoufandeh M, Liu Y, Bloch D, Greenfield C, Klink IN, Jain M, Wanunu M, Rouhanifard SH.   +13 more
europepmc   +1 more source

Perturbation of RNA homeostasis impairs mitochondrial respiration during poxvirus infection through excess RNA accumulation. [PDF]

Proc Natl Acad Sci U S A
Brahim Belhaouari D, Pant A, Navarro-Forero S, Cantu F, Yang Z.   +4 more
europepmc   +1 more source