Results 81 to 90 of about 1,806,143 (218)
Linking pseudouridine synthases to growth, developmentand cell competition [PDF]
, 2010 Eukaryotic pseudouridine synthases direct RNA pseudouridylation and bind H⁄ACA small nucleolar RNA (snoRNAs), which, in turn, may act as precursors of microRNA-like molecules.
FURIA, MARIA +2 more
core
The Emerging Field of Epitranscriptomics in Neurodevelopmental and Neuronal Disorders
Frontiers in Bioengineering and Biotechnology, 2018 Analogous to DNA methylation and histone modifications, RNA modifications represent a novel layer of regulation of gene expression. The dynamic nature and increasing number of RNA modifications offer new possibilities to rapidly alter gene expression ...
Margarita T. Angelova +6 more
doaj +1 more source
A Pseudouridine Isoxazolidinyl Nucleoside Analogue Structural Analysis: A Morphological Approach
Molecules, 2018 An in silico study has been conducted upon (3′RS,5′SR)-5-[2′-benzyl-5′-hydroxymethyl-1′,2′-isoxazolidin-3′-yl]uracil through a molecular dynamics/docking approach that highlights its potential inhibitory activity upon the wild-type pseudouridine 5 ...
Giuseppe Floresta +7 more
doaj +1 more source
EnsemPseU: Identifying Pseudouridine Sites With an Ensemble Approach
IEEE Access, 2020 Pseudouridine (Ψ) is the most prevalent RNA modification, which is formed from uridine through an isomerization reaction. With the increasing availability of genomic and proteomic samples, computer-aided pseudouridine-synthase-specific Ψ ...
Yue Bi, Dong Jin, Cangzhi Jia
doaj +1 more source
How Epitranscriptomic Machinery Senses Environmental Cues
Advanced Biology, Volume 10, Issue 9, September 2026.Exogenous exposures, microenvironmental signals, and intracellular metabolic or redox states can alter RNA‐modification machinery through catalytic chemistry, signaling‐dependent PTMs, compartmental redistribution, or changes in abundance and composition.
Shayan Jalali, Ehsan Pashay Ahi
wiley +1 more source
Agricultural and Food Science, 2008 The potential of the spot urine sampling technique to assess urinary pseudouridine excretion was evaluated. Twelve multiparous Holstein-Friesian cows were fed two experimental diets in a complete change-over design with two 14 day experimental periods ...
K. SHINGFIELD, N.W. OFFER
doaj
Pseudouridine metabolism in bacteria and mammals
, 2010 Pseudouridine is the most common modified nucleoside in RNA. It is found in ribosomal RNAs, transfer RNAs, small nuclear RNAs and small nucleolar RNAs of ail species. Pseudouridine results from the isomerization of uridine at the polynucleotide level. It
Preumont, Alice
core
Synthesis and Antiviral Evaluation of Sugar‐Modified Pseudouridine Analogs
The pyrimidine C ‐nucleoside pseudouridine (Ψ) is a ubiquitous RNA modification that enhances the stability, modulates immunogenicity, and influences the biological function of natural and ...
Elisabetta Groaz +4 more
core +1 more source
Pseudouridine-Free Escherichia coli Ribosomes
, 2018 Pseudouridine (Ψ) is present at conserved, functionally important regions in the ribosomal RNAs (rRNAs) from all three domains of life. Little, however, is known about the functions of Ψ modifications in bacterial ribosomes.
Margus Leppik +2 more
core +1 more source
Evolution of Eukaryal and Archaeal Pseudouridine Synthase Pus10 [PDF]
, 2018 Fitzek E, Joardar A, Gupta R, Geisler M. Evolution of Eukaryal and Archaeal Pseudouridine Synthase Pus10. Journal of Molecular Evolution.
Fitzek, Elisabeth +7 more
core +1 more source