Results 71 to 80 of about 499,109 (301)

Novel Opioids: Systematic Web Crawling Within the e-Psychonauts’ Scenario

open access: yesFrontiers in Neuroscience, 2020
BackgroundA wide range of novel psychoactive substances (NPSs) are regularly searched and discussed online by e-psychonauts. Among NPSs, the range of prescription/non-prescription opioids (fentanyl and non-fentanyl analogs) and herbal derivatives ...
Davide Arillotta   +13 more
doaj   +1 more source

Psychoactive substances and violent offences: A retrospective analysis of presentations to an urban emergency department in Switzerland. [PDF]

open access: yes, 2018
Psychoactive substances are often regarded as causal factors contributing to violent injuries, sexual abuse and homicides. While these effects have been demonstrated for some substances (e.g.
Meret Ricklin   +10 more
core   +3 more sources

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

open access: yesAdvanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li   +10 more
wiley   +1 more source

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

open access: yesAdvanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu   +13 more
wiley   +1 more source

Recent Changes in Drug Abuse Scenarios: The New/Novel Psychoactive Substances (NPS) Phenomenon

open access: yesBrain Sciences, 2018
Over the last decade, the emergence of a vast range of new/novel/emerging psychoactive substances (NPS) has progressively changed drug market scenarios, which have shifted from the ‘street’ to a ‘virtual’/online environment. [...]
Fabrizio Schifano
doaj   +1 more source

Analyzing the Open/Deep Web to Better Understand the New/Novel Psychoactive Substances (NPS) Scenarios: Suggestions from CASSANDRA and NPS.Finder Research Projects

open access: yesBrain Sciences, 2020
New/novel psychoactive substances (NPS) are defined as new narcotic/psychotropic drugs which are not controlled by the United Nations’ 1961 Narcotic Drugs/1971 Psychotropic Substances conventions, but which may pose a public health threat [...]
Fabrizio Schifano
doaj   +1 more source

Regulation of new psychoactive substances [PDF]

open access: yes, 2020
Backround: New psychoactive substances are substances that are not controlled by existing legislation and are created to replace already banned addictive substances, from which they are often derived.
Kozová, Johana
core  

Immigration detention centers as torturing environments: Ethical reckonings, radical refusals, and implications for a psychology of resistance

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract This paper examines psychologists' ethical dilemmas in immigration detention centers. Using critical psychology, border, and detention scholarship, it highlights psychologists' historical complicity in state violence, from the U.S. Enhanced Interrogation Program to current border regimes.
Francesca Esposito   +6 more
wiley   +1 more source

Australian Practitioners' Beliefs, Confidence, and Training Needs for Delivering Behaviour Support to Children and Young People in Out‐of‐Home Care

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Children in out‐of‐home care (OOHC) frequently present with complex behavioural needs. In New South Wales (NSW), behaviour support plans (BSPs) are mandated when restrictive practices, including psychotropic medication, are used. Little research has examined whether the statutory workforce is adequately prepared to meet behaviour support ...
Manisha Abayakoon Stanborough   +4 more
wiley   +1 more source

Methylphenidate-based novel psychoactive substances: temporary class drug order recommendations. [PDF]

open access: yes, 2016
Methylphenidate was developed as a central nervous system (CNS) stimulant in the 1960s. It acts primarily as a re-uptake inhibitor for dopamine and norepinephrine and has found widespread application in the treatment of Attention Deficit Hyperactivity ...

core  

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