Results 1 to 10 of about 50,638 (232)

Maternal mental disorders, psychotropic drugs, socioeconomic status, and offspring congenital anomalies [PDF]

open access: yesJournal of International Medical Research
Objective To evaluate whether there is an association between maternal mental health, purchase of psychotropic drugs, socioeconomic status and major congenital anomalies in offspring.
Satu-Maarit Björkstedt   +6 more
doaj   +2 more sources

Analysis of prescription and dispensation of psychotropic medications in two cities in the State of São Paulo, Brazil [PDF]

open access: yesBrazilian Journal of Psychiatry, 2002
OBJECTIVES: To investigate the prescription and dispensation of psychotropic medications through the analysis of the prescriptions/notices kept at various institutions in two cities in the state of São Paulo. METHODS: The prescriptions kept at drugstores,
Ana Regina Noto   +11 more
doaj   +1 more source

Comparative study on main compounds and hypoglycemic effects of dispensing granules of Coptidis Rhizoma and Scutellaria–Coptis herb couple with traditional decoction

open access: yesChinese Medicine, 2023
Background The clinical applications of dispensing granules (DG) have increased dramatically. However, it is controversial whether the DG has the same quality and efficacy compared with traditional decoction (TD).
Huanhuan Yu   +7 more
doaj   +1 more source

The Role of Epigenetic Modifications in Neurotoxicity Induced by Neonatal General Anesthesia

open access: yesFrontiers in Molecular Neuroscience, 2022
It has been widely demonstrated by numerous preclinical studies and clinical trials that the neonates receiving repeated or long-time general anesthesia (GA) could develop prolonged cognitive dysfunction.
Lin-Hui Ma   +8 more
doaj   +1 more source

Transferrin-Pep63-liposomes accelerate the clearance of Aβ and rescue impaired synaptic plasticity in early Alzheimer’s disease models

open access: yesCell Death Discovery, 2021
Alzheimer’s disease (AD) is characterized by aberrant accumulation of extracellular β-amyloid (Aβ) peptides in the brain. Soluble Aβ oligomers are thought to be the most neurotoxic species and are correlated with cognitive dysfunction in early AD ...
Xiu Yang   +13 more
doaj   +1 more source

A common neuronal ensemble in nucleus accumbens regulates pain-like behaviour and sleep

open access: yesNature Communications, 2023
A comorbidity of chronic pain is sleep disturbance. Here, we identify a dual-functional ensemble that regulates both pain-like behaviour induced by chronic constrictive injury or complete Freund’s adjuvant, and sleep wakefulness, in the nucleus accumbens
Haiyan Sun   +8 more
doaj   +1 more source

Transcranial Electrical Stimulation for Relief of Peripartum Mental Health Disorders in Women Undergoing Cesarean Section With Combined Spinal–Epidural Anesthesia: A Pilot Randomized Clinical Trial

open access: yesFrontiers in Psychiatry, 2022
ObjectiveThis study aimed to explore transcranial electrical stimulation (tES) to relieve peripartum anxiety and depressive symptoms in women undergoing cesarean section with combined spinal–epidural anesthesia.MethodsThis double-blind, randomized, sham ...
Qiu Zhao   +30 more
doaj   +1 more source

Post-Translational Modification of Cav1.2 and its Role in Neurodegenerative Diseases

open access: yesFrontiers in Pharmacology, 2022
Cav1.2 plays an essential role in learning and memory, drug addiction, and neuronal development. Intracellular calcium homeostasis is disrupted in neurodegenerative diseases because of abnormal Cav1.2 channel activity and modification of downstream Ca2 ...
Yun Li   +4 more
doaj   +1 more source

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