Results 1 to 10 of about 100,051 (354)

Trajectories of mental health before and after old-age and disability retirement : a register-based study on purchases of psychotropic drugs [PDF]

, 2012
WOS:000308570400003OBJECTIVES: Retirement from paid work is a major life event facing increasingly large numbers of people in the coming years. We examined trajectories of mental health five years before and five years after old-age and disability ...
Gould, Raija, Laaksonen, Mikko, Lahelma, Eero, Martikainen, Pekka, Metsä-Simola, Niina, Partonen, Timo, Pietiläinen, Olli, Rahkonen, Ossi   +7 more
core   +1 more source

Chemical Analysis of Suspected Unrecorded Alcoholic Beverages from the States of São Paulo and Minas Gerais, Brazil

Journal of Analytical Methods in Chemistry, 2015
Our study analyzed 152 samples of alcoholic beverages collected from the states of São Paulo and Minas Gerais, Brazil, using gas chromatography with flame ionization detection (GC-FID) and mass spectrometry (GC-MS), Fourier transform infrared ...
Giuseppina Negri, Julino Assunção Rodrigues Soares Neto, Elisaldo Luiz de Araujo Carlini   +2 more
doaj   +1 more source

The activation of GABAergic neurons in the hypothalamic tuberomammillary nucleus attenuates sevoflurane and propofol-induced anesthesia in mice

Frontiers in Pharmacology, 2023
Background: The histaminergic neurons in the hypothalamic tuberomammillary nucleus (TMN) have been suggested to play a vital role in maintaining a rising state.
Jing Liu, Jing Liu, Jing Liu, Jing Liu, Xiao Liu, Xiao Liu, Xiao Liu, Wen-Yu Zhou, Wen-Yu Zhou, Wen-Yu Zhou, Jun Gan, Jun Gan, Jun Gan, Jie Wang, Jie Wang, Jie Wang, Qi Zhang, Qi Zhang, Qi Zhang, Jun-Liang Li, Jun-Liang Li, Jun-Liang Li, Zhong-Shan Shen, Zhong-Shan Shen, Zhong-Shan Shen, Yue-Ying Zhang, Qiong-Yao Tang, Qiong-Yao Tang, Qiong-Yao Tang, Zhe Zhang, Zhe Zhang, Zhe Zhang   +31 more
doaj   +1 more source

Aberrant expression of FBXO22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice

Frontiers in Aging Neuroscience, 2022
Recent observation demonstrated that prolonged anesthesia modifies brain synaptic architecture in all ages, including adult. Propofol is the most commonly utilized anesthetics at clinic.
Xiaoxuan Yang, Chen Chen, Chen Chen, Dongmei Qu, Yanping Liu, Yanping Liu, Ning Wang, Ning Wang, Haibi Wang, Haibi Wang, Youjia Fan, Yushan Zhou, Buwei Yu, Qingsheng Xue, Yuqing Wu, Yuqing Wu, Han Lu   +16 more
doaj   +1 more source

Free acquisition of psychotropic drugs by the Brazilian adult population and presence on the National List of Essential Medicines [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2022
The aims of the present study were to estimate the free-of-charge acquisition of psychotropic drugs among Brazilian adults; analyze the distribution of psychotropics according to their presence on the Relação Nacional de Medicamentos Essenciais (RENAME ...
Patrícia Silveira Rodrigues, Priscila Maria Stolses Bergamo Francisco, Andréia Turmina Fontanella, Karen Sarmento Costa   +3 more
doaj   +1 more source

Two parallel medial prefrontal cortex-amygdala pathways mediate memory deficits via glutamatergic projection in surgery mice

Cell Reports, 2023
Summary: The neural circuit mechanisms underlying postoperative cognitive dysfunction (POCD) remain elusive. We hypothesized that projections from the medial prefrontal cortex (mPFC) to the amygdala are involved in POCD.
Xiao-Yu Sun, Le Liu, Yu-Tong Song, Tong Wu, Teng Zheng, Jing-Ru Hao, Jun-Li Cao, Can Gao   +7 more
doaj  

Dissecting the novel abilities of aripiprazole: The generation of anti-colorectal cancer effects by targeting Gαq via HTR2B

Acta Pharmaceutica Sinica B, 2023
Colorectal cancer (CRC) is a type of malignant tumor that seriously threatens human health and life, and its treatment has always been a difficulty and hotspot in research.
Haowei Liu, Qiuming Huang, Yunqi Fan, Bo Li, Xuemei Liu, Changhua Hu   +5 more
doaj  

Initiation of Psychotropic Medication after Partner Bereavement: A Matched Cohort Study [PDF]

, 2013
Background Recent changes to diagnostic criteria for depression in DSM-5 remove the bereavement exclusion, allowing earlier diagnosis following bereavement.
A Bourke, AL Forte, Christina R. Victor, Derek G. Cook, DM Fick, DS Davydow, E Bui, EL Fosbøl, G Brown, Iain M. Carey, J Glass, J Möller, J Warner, James Coyne, JC Wakefield, JD Lewis, JM Cook, M Stroebe, ME Charlson, R Mojtabai, S Zisook, S Zisook, SM Shah, SM Shah, SM Shah, Stephen DeWilde, Sunil M. Shah, Tess Harris   +27 more
core   +3 more sources

Hepatotoxicity of Psychotropic Drugs [PDF]

Hepatology, 1999
Psychotropic drugs with hepatotoxic potential can be classified based on their intended use: 1) antipsychoticsneuroleptics including phenothiazines, butyrophenones, and clozapine; 2) antidepressants including tricyclics, serotonin reuptake inhibitors, and monoamine oxidase (MAO) inhibitors; 3) anti-anxiety drugs such as benzodiazepines; 4 ...
Khaled Selim, Neil Kaplowitz
openaire   +3 more sources

Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson’s disease model mice

Cell Death and Disease
Neuroinflammation is a key factor in the pathogenesis of Parkinson’s disease (PD). Activated microglia in the central nervous system (CNS) and infiltration of peripheral immune cells contribute to dopaminergic neuron loss. However, the role of peripheral
Wei Song, Zi-ming Zhou, Le-le Zhang, Hai-feng Shu, Jin-ru Xia, Xia Qin, Rong Hua, Yong-mei Zhang   +7 more
doaj   +1 more source