Results 201 to 210 of about 147,647 (257)

Heterogeneity of miRNAs in Salivary Gland Neoplasms: An Exploratory Pilot Study

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Introduction MicroRNAs (miRNAs) are small RNAs that have been associated with tumourigenesis and tumour progression and that play an important role in the pathogenesis of salivary gland neoplasms. The aim of this study was to evaluate the global miRNA expression profile in a sample of salivary gland neoplasms.
Dandara Andrade de Santana, Poliana Ramos Braga, Daniel Araki Ribeiro, Patricia Ramos Cury, Ana Carolina Velasco Pondé de Sena, Flávia Caló de Aquino Xavier, Fernando Augusto Soares, Iguaracyra Barreto de Araújo, Fabio Albuquerque Marchi, Valéria Souza Freitas, Cláudia Malheiros Coutinho‐Camillo, Jean Nunes dos Santos   +11 more
wiley   +1 more source

RETRACTED: Wen et al. PTEN Deficiency Induced by Extracellular Vesicle miRNAs from <i>Clonorchis sinensis</i> Potentiates Cholangiocarcinoma Development by Inhibiting Ferroptosis. <i>Int. J. Mol. Sci.</i> 2024, <i>25</i>, 10350. [PDF]

Int J Mol Sci
Wen L, Li M, Yin J.
europepmc   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

[Expression of Rho-related BTB domain-containing protein 1 in tongue squamous cell carcinoma and its effect on cell proliferation, invasion, and migration]. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi
Shao Y, Wang Y, Yu W, Xu Y, Xu J, Wang X, Chen Z.   +6 more
europepmc   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Pathological complete response to perioperative treatment with darolutamide plus ADT in locally advanced prostate cancer without PTEN or RB1 loss: a case report. [PDF]

Front Pharmacol
Zhang Z, Zhai J, Ma Q, Xiang Y, Kan J, Chu J, Wei C, Wang M.   +7 more
europepmc   +1 more source

Identification of Novel Therapeutic Agent Candidates Through High Throughput Screening With Chemical Library Based on Molecular Subclassification in Canine Histiocytic Sarcoma Cell Lines

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Effective chemotherapy for canine histiocytic sarcoma (CHS) has yet to be established. In our previous study, CHS cell lines were subclassified into two groups based on their gene expression profiles: Group A and Group B. This study aimed to identify novel therapeutic agents that are effective against each CHS subgroup, and we performed high ...
Hiroki Sakuma, Hirotaka Tomiyasu, Mari Takamiya, Yuko Goto‐Koshino, Atsushi Tsukamoto, Makoto Bonkobara, Masaru Okuda   +6 more
wiley   +1 more source

Impact of Genomic Mutations on the Transcriptional Pathways and Tumor Microenvironment Landscape of Localized Early Prostate Cancer. [PDF]

Prostate
Lautert-Dutra W, Melo CM, Chaves LP, Souza FC, Talebian V, Crozier C, Quintayo MA, Liao L, Dion D, Saggioro FP, Avante FS, Dos Reis RB, Squire JA, Bayani J.   +13 more
europepmc   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

HIF1 inhibition targets tumoral and myeloid cells, and is a promising therapy for metastatic castration-resistant prostate cancer. [PDF]

Cell Death Dis
Yanushko D, Pichot A, Vincent A, Keime C, Laverny G, Metzger D.   +5 more
europepmc   +1 more source