Results 1 to 10 of about 10,666 (255)
Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 Ricin toxin A chain (RTA), from Ricinus communis, is a deadly protein that inactivates ribosomes by degrading an adenine residue at position 4324 in 28S rRNA. Recently, we have demonstrated that pterin-7-carboxamides with peptide pendants were potent RTA
Masaru Goto +5 more
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Pterin-Based Red Coloration Predicts the Outcome of Male–Male Competition in Guinan Toad-Headed Lizard [PDF]
AnimalsAnimal coloration offers a unique opportunity to explore the evolutionary mechanisms underlying phenotypic diversity. Conspicuous coloration caused by pigments plays a crucial role in social signaling across multiple species by conveying information ...
Xiao Xiao +8 more
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Mechanistic Study of ROS-photogeneration by Pterin
Pteridines, 2011 Pterins are widespread in biological systems and possess photosensitizing activities. In the present study, the photosensitization mechanism of acid form of pterin (PTA) and basic form of pterin (PTB) is investigated by means of density functional theory
Ji Hong-Fang, Shen Liang
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Comparative metabolism of conjugated and unconjugated pterins in Crithidia, Leishmania and African trypanosomes. [PDF]
PLoS Neglected Tropical DiseasesMammalian cells synthesise tetrahydrobiopterin de novo, an essential cofactor for hydroxylation of aromatic amino acids, cleavage of ether lipids and the synthesis of nitric oxide.
Han B Ong, Susan Wyllie, Alan H Fairlamb
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Paper Chromatography of Pterins [PDF]
Nature, 1949 THE detection and identification of pterins in small quantities was carried out by Schopf and Becker1 in the course of their classical work on this class of pigments. They employed a chromatographic technique using 0·004 N aqueous hydrochloric acid or 0·01 N methyl alcoholic hydrochloric acid solutions on micro-absorption columns of alumina or ...
P M, GOOD, A W, JOHNSON
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Mechanism of soil bacteria (Cupriavidus sp. LA-1) for degrading natural pterin and lumazine pigments [PDF]
Communications BiologyDiverse microbial metabolic mechanisms help maintain the environmental dynamics of natural compounds in biogeochemical cycles. This study revealed the bacterial mechanism for degrading pterin and lumazine compounds, which are natural cofactors and ...
Yuki Doi, Norifumi Maeda, Naoki Takaya
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Making Moco: A Personal History [PDF]
Molecules, 2023 This contribution describes the path of my nearly forty-year quest to understand the special ligand coordinated to molybdenum and tungsten ions in their respective enzymes.
Sharon J. Nieter Burgmayer
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Pushing at the Boundaries of Pterin Chemistry [PDF]
MoleculesPterins are molecules of substantial interest as they occur in nature in a number of forms with quite distinct and often indispensable roles. Chemically, the synthesis of the principle pterin scaffold is comparably simple, while the insolubility of the ...
Jevy V. Correia +2 more
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Pterin function in bacteria [PDF]
Pteridines, 2017 Pterins are widely conserved biomolecules that play essential roles in diverse organisms. First described as enzymatic cofactors in eukaryotic systems, bacterial pterins were discovered in cyanobacteria soon after.
Feirer Nathan, Fuqua Clay
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Pterin Metabolism In Haemodialysis Patients
Pteridines, 1989 Patients undertaking maintenance haemodialysis may develop a variety of neurological disorders, the most serious of which is aluminium induced encephalopathy.
Altmann Paul +5 more
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