Results 11 to 20 of about 10,666 (255)
Calcium pterin as an antitumor agent
International Journal of Pharmaceutics, 2004 A series of in vivo studies are reported that provide evidence for an immunologically mediated mechanism for the antitumor response from a calcium pterin (CaPterin) suspension. Strong antitumor efficacy was demonstrated in fully immunocompetent female C3H/HeN-MTV+ mice (retired breeders) presenting spontaneous mammary gland adenocarcinomas.
Phillip B. B. Moheno
openaire +3 more sources
Pterin-based pigmentation in animals [PDF]
Biology Letters, 2021 Pterins are one of the major sources of bright coloration in animals. They are produced endogenously, participate in vital physiological processes and serve a variety of signalling functions. Despite their ubiquity in nature, pterin-based pigmentation has received little attention when compared to other major pigment classes.
Pedro Andrade, Miguel Carneiro
openaire +2 more sources
Comparative routes to 7-carboxymethyl-pterin: A useful medicinal chemistry building block
Pteridines, 2022 Pterins, such as folate and biopterin, and their derivatives hold significant importance given their biological relevance, as well as the numerous pterin-based inhibitors developed for targeting various biological targets. For this reason, pterins can be
Bennett Zachary +2 more
doaj +1 more source
Orientation of Pterin-6-Carboxylic Acid on Gold Capped Silicon Nanopillars Platforms: Surface Enhanced Raman Spectroscopy and Density Functional Theory Studies [PDF]
, 2015 The orientation of pterin-6-carboxylic acid on gold nanopillars was investigated by surface enhanced Raman spectroscopy and density functional theory methods.
John J. Castillo +6 more
openalex +3 more sources
Synthesis, Characterization and Chlorination of 4-(Pentyloxy)-7-(prop-2-yn-1-yloxy)pteridin-2-amine
Molbank, 2023 A new alkyne functionalized pterin derivative was synthesized through a reaction of 7-chloropterin with propargyl alcohol in the presence of sodium hydride.
Jevy V. Correia +2 more
doaj +1 more source
Comparison of Pteridine Normalization Methods in Urine for Detection of Bladder Cancer
Diagnostics, 2020 Pterin compounds belong to the group of biomarkers for which an increase in interest has been observed in recent years. Available literature data point to this group of compounds as potential biomarkers for cancer detection, although the biochemical ...
Piotr Kośliński +6 more
doaj +1 more source
Synthesis, Redox and Spectroscopic Properties of Pterin of Molybdenum Cofactors
Molecules, 2022 Pterins are bicyclic heterocycles that are found widely across Nature and are involved in a variety of biological functions. Notably, pterins are found at the core of molybdenum cofactor (Moco) containing enzymes in the molybdopterin (MPT) ligand that ...
Kyle J. Colston, Partha Basu
doaj +1 more source
Exploring the scope of DBU-promoted amidations of 7-methoxycarbonylpterin
Beilstein Journal of Organic Chemistry, 2020 The synthetic utility of pterins is often hampered by the notorious insolubility of this heterocycle, slowing the development of medicinally relevant pteridine derivatives.
Anna R. Bockman, Jeffrey M. Pruet
doaj +1 more source
Results in Chemistry, 2023 Antimicrobial resistance has rendered the sulfonamide class of antibiotics obsolete. An additional binding site on the dihydropteroate synthase (DHPS) enzyme, i.e., the pterin binding site, has been shown to be a valid alternative to the well-known para ...
Maryké Shaw +3 more
doaj +1 more source
Acta Crystallographica Section E, 2013 In the title complex, [Ni(C8H5N5O3)(C2H8N2)(C3N2H4)]·2H2O, a tridentate 2-amino-7-methyl-4-oxidopteridine-6-carboxylate (pterin) ligand, a bidentate ancillary ethane-1,2-diamine (en) ligand and a monodentate 1H-imidazole (im) ligand complete a ...
Siddhartha S. Baisya, Parag S. Roy
doaj +1 more source