Pushing at the Boundaries of Pterin Chemistry [PDF]
MoleculesPterins are molecules of substantial interest as they occur in nature in a number of forms with quite distinct and often indispensable roles. Chemically, the synthesis of the principle pterin scaffold is comparably simple, while the insolubility of the pterin building block renders synthetic derivatization extremely difficult.
Jevy V. Correia +2 more
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Photosensitization of peptides and proteins by pterin derivatives [PDF]
Pteridines, 2017 Abstract Proteins are one of the preferential targets of the photosensitized damaging effects of ultraviolet (UV) radiation on biological system. Pterins belong to a family of heterocyclic compounds, which are widespread in living systems and participate in relevant biological functions.
Dántola, María Laura +5 more
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Synthesis, Redox and Spectroscopic Properties of Pterin of Molybdenum Cofactors
Molecules, 2022 Pterins are bicyclic heterocycles that are found widely across Nature and are involved in a variety of biological functions. Notably, pterins are found at the core of molybdenum cofactor (Moco) containing enzymes in the molybdopterin (MPT) ligand that ...
Kyle J. Colston, Partha Basu
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Making Moco: A Personal History [PDF]
Molecules, 2023 This contribution describes the path of my nearly forty-year quest to understand the special ligand coordinated to molybdenum and tungsten ions in their respective enzymes.
Sharon J. Nieter Burgmayer
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Pterin-Based Red Coloration Predicts the Outcome of Male–Male Competition in Guinan Toad-Headed Lizard [PDF]
AnimalsAnimal coloration offers a unique opportunity to explore the evolutionary mechanisms underlying phenotypic diversity. Conspicuous coloration caused by pigments plays a crucial role in social signaling across multiple species by conveying information ...
Xiao Xiao +8 more
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Photoinduced cleavage of plasmid DNA in the presence of pterin [PDF]
Pteridines, 2000 The photoinduced cleavage of plasmid DNA by UV -A light in the presence of pterin was investigated. Electrophoretic analysis of the irradiated plasmid pUCI8 in the presence of pterin showed that UV light of 350 nm induced the transformation of a ...
Lorente Carolina +5 more
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Regulatory changes in pterin and carotenoid genes underlie balanced color polymorphisms in the wall lizard [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Reptiles show an amazing color diversity based on variation in melanins, carotenoids, and pterins. This study reveals genes controlling differences between three color morphs (white, orange, and yellow) in the common wall lizard.
Pedro Andrade +23 more
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Novel role of folate (vitamin B9) released by fermenting bacteria under Human Intestine like environment [PDF]
Scientific Reports, 2023 The anaerobic region of the gastrointestinal (GI) tract has been replicated in the anaerobic chamber of a microbial fuel cell (MFC). Electroactive biomolecules released by the facultative anaerobes (Providencia rettgeri) under anoxic conditions have been
Sharda Nara +3 more
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Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 Ricin toxin A chain (RTA), from Ricinus communis, is a deadly protein that inactivates ribosomes by degrading an adenine residue at position 4324 in 28S rRNA. Recently, we have demonstrated that pterin-7-carboxamides with peptide pendants were potent RTA
Masaru Goto +5 more
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Implications of Pyran Cyclization and Pterin Conformation on Oxidized Forms of the Molybdenum Cofactor [PDF]
Journal of the American Chemical Society, 2018 The large family of mononuclear molybdenum and tungsten enzymes all possess the special ligand molybdopterin (MPT), which consists of a metal-binding dithiolene chelate covalently bound to a pyranopterin group.
Douglas R. Gisewhite +6 more
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