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Molecular Insights Into MR1‐Mediated T Cell Immunity: Lessons Learned and Unanswered Questions [PDF]

open access: yesImmunological Reviews, Volume 331, Issue 1, May 2025.
ABSTRACT The major histocompatibility complex class‐I related protein, MR1, is an evolutionarily conserved antigen presenting molecule that binds and displays organic metabolites to T cells, including mucosal associated invariant T (MAIT) cells and diverse MR1‐restricted T cells (MR1T). Structural studies have elucidated how MR1 can accommodate a range
Wael Awad   +4 more
wiley   +2 more sources

A contribution to the chemistry of pterins [PDF]

open access: bronzeProceedings of the Royal Society of London. Series B - Biological Sciences, 1942
The experiments in this paper have been chiefly concerned with a derivative from pterins, the wing pigments of pierid butterflies. These pigments have become prominent of recent years, partly on account of the prolonged efforts (1925-41) of continental workers to determine their nature.
Frederick Gowland Hopkins
openaire   +3 more sources

Pterin–sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents [PDF]

open access: greenBioorganic & Medicinal Chemistry Letters, 2016
Ying Zhao   +8 more
openalex   +2 more sources

An ab initio and density functional theory study on neutral pterin radicals

open access: yesPteridines, 2015
The electronic structures of the five radicals resulting from homolytic elimination of one of the hydrogen atoms from the most stable tautomeric form of neutral pterin were investigated in gas phase as well as in aqueous solution.
Reibnegger Gilbert
doaj   +2 more sources

6-(D-ribo-tetrahydroxybutyl)pterin from Rhodopseudomonas sphaeroides [PDF]

open access: hybridPteridines, 1993
Hariu Tetsutaro   +3 more
doaj   +2 more sources

Effect of pterin impurities on the fluorescence and photochemistry of commercial folic acid [PDF]

open access: greenJournal of Photochemistry and Photobiology. B: Biology, 2018
M. Laura Dántola   +2 more
openalex   +2 more sources

Mechanism of molybdate insertion into pterin-based molybdenum cofactors.

open access: yesNature Chemistry, 2021
The molybdenum cofactor (Moco) is found in the active site of numerous important enzymes that are critical to biological processes. The bidentate ligand that chelates molybdenum in Moco is the pyranopterin dithiolene (molybdopterin, MPT).
Corinna Probst   +11 more
semanticscholar   +1 more source

Comparative routes to 7-carboxymethyl-pterin: A useful medicinal chemistry building block

open access: yesPteridines, 2022
Pterins, such as folate and biopterin, and their derivatives hold significant importance given their biological relevance, as well as the numerous pterin-based inhibitors developed for targeting various biological targets. For this reason, pterins can be
Bennett Zachary   +2 more
doaj   +1 more source

Synthesis, Characterization and Chlorination of 4-(Pentyloxy)-7-(prop-2-yn-1-yloxy)pteridin-2-amine

open access: yesMolbank, 2023
A new alkyne functionalized pterin derivative was synthesized through a reaction of 7-chloropterin with propargyl alcohol in the presence of sodium hydride.
Jevy V. Correia   +2 more
doaj   +1 more source

Comparison of Pteridine Normalization Methods in Urine for Detection of Bladder Cancer

open access: yesDiagnostics, 2020
Pterin compounds belong to the group of biomarkers for which an increase in interest has been observed in recent years. Available literature data point to this group of compounds as potential biomarkers for cancer detection, although the biochemical ...
Piotr Kośliński   +6 more
doaj   +1 more source

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