Synthesis of 6-Hydroxymethylpterin α- and β-D-Glucosides [PDF]
The key precursor, N(2)-(N,N-dimethylaminomethylene)-6-hydroxymethyl-3-[2-(4-nitrophenyl)ethyl]pterin (11) was efficiently prepared from 2,5,6-triamino-4-hydroxypyrimidine (8) in 5 steps.
Baba, Hiroki +3 more
core +1 more source
Inhibitory Effects of Pteridines on the Cytochrome P-450 Enzyme System
The effects of 17 different pteridine derivatives on rat liver microsomal cytochrome P-450 catalyzed degradation of aminoantipyrin were studied.
Horejsi Renate +5 more
doaj +1 more source
Molecular architecture of pterin deaminase from Saccharomyces cerevisiae NCIM 3458
As early as 1974, reports have confirmed the anticancer activity of pterin deaminase isolated from fungi. The enzyme has also been reported in bacteria, fungi and slime mold genera, but the enzyme characterization was effetely done.
Murugesan Thandeeswaran +7 more
doaj +1 more source
Immunopterin: A prospective therapy and preventative to fight COVID-19?
The authors explore the therapeutic and prophylactic efficacies of Immunopterin (calcium pterin-6-carboxylate chelate) against coronavirus colds and as a therapy against COVID-19.
Moheno Phillip B. B., Fuchs Dietmar
doaj +1 more source
Plasma Levels of Neopterin and Biopterin in the Umbilical Vessels and the Maternal Vein
Tetrahydrobiopterin (BH4) is a highly bioactive pterin required for nitric oxide synthase and monooxygenases of aromatic amino acids, and is involved in the synthesis of nitric oxide, catecholamines and Serotonin.
Iwanaga Naoko +8 more
doaj +1 more source
Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation. [PDF]
The crystal structure of Dhaf4260 from Desulfitobacterium hafniense DCB-2 was determined by single-wavelength anomalous diffraction (SAD) to a resolution of 2.01 Å using the semi-automated high-throughput pipeline of the Joint Center for Structural ...
Abdubek, Polat +37 more
core +3 more sources
The anaerobic region of the gastrointestinal (GI) tract has been replicated in the anaerobic chamber of a microbial fuel cell (MFC). Electroactive biomolecules released by the facultative anaerobes (Providencia rettgeri) under anoxic conditions have been
Sharda Nara +3 more
doaj +1 more source
Theoretical Study on the Relative Energies of Anionic Pterin Tautomers
Pterins exist as several tautomeric forms and behave as weak acids in aqueous solutions. Therefore, several acidbase equilibria may be present. For several pterin derivatives, the range of the experimental pKa lies in the range 6-8.
Soniat Michael, Martin Christopher B.
doaj +1 more source
Mechanistic Study of ROS-photogeneration by Pterin
Pterins are widespread in biological systems and possess photosensitizing activities. In the present study, the photosensitization mechanism of acid form of pterin (PTA) and basic form of pterin (PTB) is investigated by means of density functional theory
Ji Hong-Fang, Shen Liang
doaj +1 more source
Eumelanin and pheomelanin are predominant pigments in bumblebee (Apidae: Bombus) pubescence [PDF]
Background: Bumblebees (Hymenoptera: Apidae: Bombus) are well known for their important inter- and intra-specific variation in hair (or pubescence) color patterns, but the chemical nature of the pigments associated with these patterns is not fully ...
Alberto, Jorge +2 more
core +2 more sources

