Molecular Insights Into MR1‐Mediated T Cell Immunity: Lessons Learned and Unanswered Questions [PDF]
ABSTRACT The major histocompatibility complex class‐I related protein, MR1, is an evolutionarily conserved antigen presenting molecule that binds and displays organic metabolites to T cells, including mucosal associated invariant T (MAIT) cells and diverse MR1‐restricted T cells (MR1T). Structural studies have elucidated how MR1 can accommodate a range
Wael Awad+4 more
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A contribution to the chemistry of pterins [PDF]
The experiments in this paper have been chiefly concerned with a derivative from pterins, the wing pigments of pierid butterflies. These pigments have become prominent of recent years, partly on account of the prolonged efforts (1925-41) of continental workers to determine their nature.
Frederick Gowland Hopkins
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Pterin–sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents [PDF]
Ying Zhao+8 more
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An ab initio and density functional theory study on neutral pterin radicals
The electronic structures of the five radicals resulting from homolytic elimination of one of the hydrogen atoms from the most stable tautomeric form of neutral pterin were investigated in gas phase as well as in aqueous solution.
Reibnegger Gilbert
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6-(D-ribo-tetrahydroxybutyl)pterin from Rhodopseudomonas sphaeroides [PDF]
Hariu Tetsutaro+3 more
doaj +2 more sources
Effect of pterin impurities on the fluorescence and photochemistry of commercial folic acid [PDF]
M. Laura Dántola+2 more
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Mechanism of molybdate insertion into pterin-based molybdenum cofactors.
The molybdenum cofactor (Moco) is found in the active site of numerous important enzymes that are critical to biological processes. The bidentate ligand that chelates molybdenum in Moco is the pyranopterin dithiolene (molybdopterin, MPT).
Corinna Probst+11 more
semanticscholar +1 more source
Comparative routes to 7-carboxymethyl-pterin: A useful medicinal chemistry building block
Pterins, such as folate and biopterin, and their derivatives hold significant importance given their biological relevance, as well as the numerous pterin-based inhibitors developed for targeting various biological targets. For this reason, pterins can be
Bennett Zachary+2 more
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Synthesis, Characterization and Chlorination of 4-(Pentyloxy)-7-(prop-2-yn-1-yloxy)pteridin-2-amine
A new alkyne functionalized pterin derivative was synthesized through a reaction of 7-chloropterin with propargyl alcohol in the presence of sodium hydride.
Jevy V. Correia+2 more
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Comparison of Pteridine Normalization Methods in Urine for Detection of Bladder Cancer
Pterin compounds belong to the group of biomarkers for which an increase in interest has been observed in recent years. Available literature data point to this group of compounds as potential biomarkers for cancer detection, although the biochemical ...
Piotr Kośliński+6 more
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