Results 241 to 250 of about 8,097,471 (281)

Vascular smooth muscle cell-derived osteoprotegerin drives pulmonary arterial hypertension via AKT activation and is attenuated by monoclonal antibody therapy. [PDF]

Cardiovasc Res
Keles M, West LE, Arnold ND, Weiss A, Mykytyuk NV, Baldauf J, Pickworth JA, Zawia AA, Turton HA, Allen MF, Ruppert C, Thompson AAR, Francis SE, Schermuly RT, Lawrie A.   +14 more
europepmc   +1 more source

Paracrine action of bone morphogenetic protein 3 in pulmonary arterial hypertension. [PDF]

Eur Respir J
Halouani A, Mensah E, Ben Rhouma M, Athumani Z, Katz MG, Imani S, Antar SA, Jankowski K, Mansoori M, Rosen V, Ishikawa K, Hadri L, Sassi Y.   +12 more
europepmc   +1 more source

Apelin-13 attenuates hyperoxia-induced pulmonary arterial smooth muscle cell dysfunction via BMPR2/IL-6 modulation in pulmonary arterial hypertension. [PDF]

Transl Pediatr
Pan F, Huang D, Mo L.
europepmc   +1 more source

Role of Interleukin 34 in Pulmonary Vascular Remodeling Associated With Fibrosing Interstitial Lung Disease. [PDF]

Pulm Circ
Yokokawa T, Ueda S, Nishiura K, Okochi S, Ogawara R, Kiko T, Miura S, Misaka T, Oikawa M, Masuishi Y, Kakamu T, Tanino Y, Shibata Y, Hashimoto Y, Muto S, Suzuki H, Inoue KI, Ikeda K, Nakazato K, Ishida T, Takeishi Y.   +20 more
europepmc   +1 more source

Abstract Supplement HIV Glasgow 8–11 November 2026, Glasgow, UK/Virtual

Journal of the International AIDS Society, Volume 29, Issue S6, November 2026.
wiley   +1 more source

RhoA Activation by Hypoxia in Pulmonary Arterial Smooth Muscle Cells Is Age and Site Specific [PDF]

Circulation Research, 2004
Hypoxia induces vasoconstriction of pulmonary arteries through contraction of smooth muscle cells (SMCs). The GTPase RhoA regulates smooth muscle contractility and actin cytoskeletal remodeling through the Rho-associated kinase ( ROCK).
Anne Ridley, Susan J Hall, Sheila G Haworth   +2 more
exaly   +2 more sources

Activation of AMPK Inhibits Pulmonary Arterial Smooth Muscle Cells Proliferation

Experimental Lung Research, 2014
The aims of the present study were to examine the effect of AMPK activation on pulmonary arterial smooth muscle cells (PASMCs) proliferation and to address its potential mechanisms. ET-1 dose and time-dependently induced PASMCs proliferation, and this effect was suppressed by a selective AMPK activator metformin.
Lu Liu, Wei Feng, Guizuo Wang
exaly   +3 more sources

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TUG1 Regulates Pulmonary Arterial Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension

Canadian Journal of Cardiology, 2019
Pulmonary arterial hypertension (PAH) is a progressive disease, characterized by a persistent elevation of pulmonary arterial pressure and pulmonary vascular remodelling. Recent studies implicated that long noncoding RNAs (lncRNAs) play important roles in the development of various diseases.
Shuang, Wang, Weiwei, Cao, Shan, Gao, Xiaowei, Nie, Xiaodong, Zheng, Yan, Xing, Yingli, Chen, Hongxia, Bao, Daling, Zhu   +8 more
openaire   +2 more sources

FOXM1 promotes pulmonary artery smooth muscle cell expansion in pulmonary arterial hypertension

Journal of Molecular Medicine, 2017
Pulmonary arterial hypertension (PAH) is a progressive vascular remodeling disease characterized by a persistent elevation of pulmonary artery pressure, leading to right heart failure and premature death. Exaggerated proliferation and resistance to apoptosis of pulmonary artery smooth muscle cells (PASMCs) is a key component of vascular remodeling ...
Alice Bourgeois, Caroline Lambert, Karima Habbout, Benoit Ranchoux, Stéphanie Paquet-Marceau, Isabelle Trinh, Sandra Breuils-Bonnet, Renée Paradis, Valérie Nadeau, Roxane Paulin, Steeve Provencher, Sébastien Bonnet, Olivier Boucherat   +12 more
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Mibefradil Suppresses the Proliferation of Pulmonary Artery Smooth Muscle Cells

Journal of Investigative Medicine, 2016
Intracellular Ca 2+ levels play a critical role in the regulation of vasodilation and vasoconstriction by stimulating pulmonary artery smooth muscle cell (PASMC) proliferation, which is important in the pathogenesis of pulmonary arterial hypertension (PAH); however, L-type Ca
Hong-Hong, Li, Li-Jian, Xie, Ting-Ting, Xiao, Min, Huang, Jie, Shen   +4 more
openaire   +2 more sources