Results 91 to 100 of about 1,730,704 (357)

Trends of a decade in risk factors of patient delay among pulmonary tuberculosis patients during fast aging and urbanization - analysis of surveillance data from 2008 to 2017 in Wuhan, China

BMC Public Health, 2023
Background Tuberculosis (TB) is a leading infectious cause of morbidity and mortality worldwide. However, delay in health care seeking has remained unacceptably high. The aim of this study was to clarify the trend of patient delay and its associated risk
Xiaojun Wang, Yuehua Li, Qian Fu, Meilan Zhou   +3 more
doaj   +1 more source

REST IN PULMONARY TUBERCULOSIS. [PDF]

JAMA: The Journal of the American Medical Association, 1906
I wish to make a plea addressed to the general practitioner for the routine employment of rest in the open air in all active or partially arrested cases of tuberculosis. In the vast majority of cases the general practitioner is the man who is called on to diagnose and to treat these patients, and as he has been lectured, criticized and cajoled into ...
openaire   +3 more sources

Appendicular mass – a rare form of tuberculosis [PDF]

, 2017
Tuberculosis is in the top 10 causes of death worldwide, being one of the most deadly infectious diseases. It is estimated that one of three people from the entire earth population has a latent infection with M tuberculosis.
Balalau, Cristian, Banu, Petrisor, Bratucu, Mircea, Constantin, Vlad D., Popa, Florian, Vladescu, Teodora   +5 more
core   +4 more sources

The Transcriptional Signature of Active Tuberculosis Reflects Symptom Status in Extra-Pulmonary and Pulmonary Tuberculosis

PLoS ONE, 2016
Background Mycobacterium tuberculosis infection is a leading cause of infectious death worldwide. Gene-expression microarray studies profiling the blood transcriptional response of tuberculosis (TB) patients have been undertaken in order to better ...
S. Blankley, C. Graham, J. Turner, M. Berry, C. Bloom, Zhaohui Xu, V. Pascual, J. Banchereau, D. Chaussabel, R. Breen, G. Santis, D. Blankenship, M. Lipman, A. O’Garra   +13 more
semanticscholar   +1 more source

Efficacy and Safety of ABBV‐154 for the Treatment of Active Rheumatoid Arthritis: A Phase 2b, Randomized, Placebo‐Controlled Trial

Arthritis &Rheumatology, Accepted Article.
Objective Despite availability of biologics and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) to treat rheumatoid arthritis (RA), many patients do not experience optimized disease control. Glucocorticoids are effective but have safety risks.
Frank Buttgereit, Atul Singhal, Alan Kivitz, Edit Drescher, Yoshinori Taniguchi, Rosalía Martínez Pérez, Jaclyn Anderson, Ronilda D'Cunha, Weihan Zhao, Nicholas DeVogel, Julie Parmentier, Romy Christmann, Dilek Arikan, Howard Amital   +13 more
wiley   +1 more source

Clinical diagnostic value of simultaneous amplification and testing for the diagnosis of sputum-scarce pulmonary tuberculosis

BMC Infectious Diseases, 2017
Background Since 20% of pulmonary tuberculosis (PTB) patients are asymptomatic, the early detection of PTB is a challenge particularly in sputum-scarce patients and diagnostic accuracy based solely on clinical characteristics and chest X-ray/CT scans are
Liping Yan, Qing Zhang, Heping Xiao
doaj   +1 more source

The feasibility of pharmacokinetic‐based dosing of hydroxyurea for children with sickle cell anaemia in Uganda: Baseline results of the alternative dosing and prevention of transfusions trial

British Journal of Clinical Pharmacology, EarlyView.
Abstract Pharmacokinetic (PK)‐guided dosing of hydroxyurea for children with sickle cell anaemia (SCA) could optimize dosing and improve outcomes, but its feasibility has not been demonstrated in low‐resource settings where the majority of affected children live.
Alexandra Power‐Hays, Ruth Namazzi, Min Dong, Caroline Kazinga, Charles Kato, Sadat Aliwuya, Kathryn McElhinney, Andrea L. Conroy, Adam Lane, Chandy John, Alexander A. Vinks, Teresa Latham, Robert O. Opoka, Russell E. Ware   +13 more
wiley   +1 more source

Epidemiological characteristics and influencing factors of tuberculosis aggregation in schools in Wuhan, China during 2017–2022

Frontiers in Public Health
BackgroundWuhan is located in the hinterland of China, in the east of Hubei Province, at the intersection of the Yangtze River and Hanshui River. It is a national historical and cultural city, an important industrial, scientific, and educational base ...
Zhengbin Zhang, Gang Wu, Aiping Yu, Jing Hu, Wei Zhang, Zhouqin Lu, Jun Wu, Lina Wang, Xiaojun Wang, Jianjie Wang, Guiyang Wang, Yuehua Li, Meilan Zhou   +12 more
doaj   +1 more source

Prediction of drug resistance profile of multidrug-resistant Mycobacterium tuberculosis (MDR-MTB) isolates from newly diagnosed case by whole genome sequencing (WGS): a study from a high tuberculosis burden country

BMC Infectious Diseases, 2022
Objectives Our aim was to assess the ability of the Whole-genome sequencing (WGS) in predicting drug resistance profile of multidrug-resistant mycobacterium tuberculosis (MDR-MTB) from newly diagnosed cases in China.
Wenwen Sun, Xuwei Gui, Zheyuan Wu, Yangyi Zhang, Liping Yan   +4 more
doaj   +1 more source

Genetic polymorphisms of IL-17A, IL-17F, TLR4 and miR-146a in association with the risk of pulmonary tuberculosis

Scientific Reports, 2016
Genetic factors affect host susceptibility to pathogens. In this population-based case control study, we explored the genetic polymorphisms of IL-17, TLR4 and miR-146a in association with pulmonary tuberculosis in a Chinese Han population.
Min Wang, Guisheng Xu, Lingshuang Lü, Kun Xu, Yongzhong Chen, H. Pan, B. Burstrom, K. Burstrom, Jianming Wang   +8 more
semanticscholar   +1 more source