Glutathione-Mediated Neuroprotective Effect of Purine Derivatives. [PDF]
Int J Mol Sci, 2023 Numerous basic studies have reported on the neuroprotective properties of several purine derivatives such as caffeine and uric acid (UA). Epidemiological studies have also shown the inverse association of appropriate caffeine intake or serum urate levels with neurodegenerative diseases such as Alzheimer disease (AD) and Parkinson’s disease (PD).
Matsumura N, Aoyama K.
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Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia. [PDF]
Pharmaceutics, 2022 We report 31 new compounds designed, synthesized and evaluated on Bcr-Abl, BTK and FLT3-ITD as part of our program to develop 2,6,9-trisubstituted purine derivatives as inhibitors of oncogenic kinases.
Bertrand J +10 more
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Thermoanalytical study of purine derivatives compounds
Eclética Química, 2018 Thermal methods of analysis are now used in a very large range of scientific investigations. In this work simultaneous thermogravimetry-differential thermal analysis (TG-DTA), X-Ray powder diffractometry and infrared spectroscopy were used to study the ...
G. F. C. Sotelo +2 more
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Purine-based chemical probe with HOMO switching for intracellular detection of mercury ions. [PDF]
Sci RepThe detailed photophysical characterization of 2-piperidinyl-6-triazolylpurine derivatives and their complexes with metal ions is presented. The studied compounds contain two electron donating units – piperidine and methoxyphenyl, while triazolyl-purine ...
Boguševičienė K +11 more
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Molecules, 2023 Synthetic unnatural base pairs have been proven to be attractive tools for the development of DNA-based biotechnology. Our group has very recently reported on alkynylated purine–pyridazine pairs, which exhibit selective and stable base-pairing via ...
Hidenori Okamura +4 more
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Total synthesis of [15N]-labelled C6-substituted purines from [15N]-formamide—easy preparation of isotopically labelled cytokinins and derivatives [PDF]
Royal Society Open Science, 2018 Cytokinins (CKs) and their metabolites and derivatives are essential for cell division, plant growth regulation and development. They are typically found at minute concentrations in plant tissues containing very complicated biological matrices. Therefore,
Jan Buček +7 more
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The effects of seasonal variation on the microbial-n flow to the small intestine and prediction of feed intake in grazing karayaka sheep [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2013 The objectives of the present study were to estimate the microbial-N flow to the small intestine and to predict the digestible organic matter intake (DOMI) in grazing Karayaka sheep based on urinary excretion of purine derivatives (xanthine, hypoxanthine,
SALMAN M, CETINKAYA N, SELCUK Z, GENC B
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Scientific African, 2020 The corrosion inhibition potential of purine and its twelve derivatives was theoretically investigated. Their chemical descriptors: dipole moments, softness, electronegativity, chemical hardness, molecular weight in conjunction with the electronic ...
B.T. Ogunyemi, D.F. Latona, I.A. Adejoro
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Biosensors, 2023 In the rapidly evolving field of food science, nanotechnology-based biosensors are one of the most intriguing techniques for tracking meat freshness.
Wen Xia Ling Felicia +5 more
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Creatinine and purine derivatives excretion and microbial synthesis in lambs fed rain tree pod meal
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2022 Evaluated the levels of rain tree (Samanea saman) pod meal (RTPM) (0, 10, 15, 20 and 25%) replacing maize in the dry matter of the diet on intake of DM, CP and ME, creatinine and total purine derivatives excretion in urine and microbial protein synthesis
L.B. Sousa +8 more
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